Conserved Protein Domain Family
Sec31

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pfam11549: Sec31 
Protein transport protein SEC31
Sec31 is involved in COPII coat formation as it forms through the sequential binding of three cytoplasmic proteins: Sar1, Sec23/24 and Sec13/31. Sec13/31 is recruited by the pre-budding complex and polymerization of Sec13/31 occurs to form an octahedral cage that is the outer shell of the COPII coat. Sec13/31 is a hetero-tetramer which is organized as a linear array of alpha-solenoid and beta-propeller domains to form a rod in which twenty-four copies assemble to form the COPII cub-octahedron.
Statistics
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PSSM-Id: 402928
View PSSM: pfam11549
Aligned: 13 rows
Threshold Bit Score: 75.2182
Threshold Setting Gi: 387514319
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
CCH61756      937 APPPQNGKsgASGQTPHLNKKANFGWNDLPIgkDATQaKPSRAKAVSIQPSNS 989  Tetrapisispora blattae CBS 6284
Q6CL75        875 APPPISGAsgYSGQTPHLHDKPIDGWNDLPS--VSKE-KPTRAKAVNTAPIGM 924  Kluyveromyces lactis NRRL Y-1140
Q6FNU4        892 SAPPVKSPsvYSGQTPHLNKKANDGWNDLAL--PVKE-KPQRAKPVTVAPSPI 941  [Candida] glabrata CBS 138
CAR30110      930 lAPPASNA--ASGQTPHLNKNANDGWNDLPL--NVKE-KPTRAKAVSVAPVSV 977  Lachancea thermotolerans CBS 6340
XP_003683822  941 PPPPI-NM--RSGQIPHLTKEANDGWNDLPL--KSKD-KPSRAKAVAVAPVAp 987  Tetrapisispora phaffii CBS 4417
EDO15909      907 PPPPITNV--KSGQTPHLNKDANDGWNDLPL--KSKE-KPSRAKPVAVSPAAS 954  Vanderwaltozyma polyspora DSM 70294
CCD22445      933 PPPVPSHM--HSGQSPHLNRKANDGWNDLPI--KIEA-KPSRAKAVSVAKTgv 980  Naumovozyma dairenensis CBS 421
XP_003959876  874 PSAPPMNRgmQSGQKPHLNKKANDGWNDLPL--KVKE-KTSRAKAVSVAPVAV 923  Kazachstania africana CBS 2517
Q75A30        892 PPVNPAATnvLSGQSPHLNRKANNGWNDLPE--IVKE-KKSRAKPVSTAPVAV 941  Eremothecium gossypii ATCC 10895
XP_001646415  893 RNPVPGNV--ISGQVPHANKKANDGWNDLPL--DVRE-KTIRAKPVSVAPVSS 940  Vanderwaltozyma polyspora DSM 70294
CCE91125      893 PPPPTV----ASGQTPSLNRKANDGWNDLPL--PVKE-KPSRAKAGSVAPVKI 938  Torulaspora delbrueckii
CDF90986      884 PPPPTM----KSGQAPHLNKKANDGWNDLPL--NVKE-KPQRAKAPSVAPINI 929  Zygosaccharomyces bailii CLIB 213
CCK68722      914 PPPPTMGAggLSGQAPHLNRKANDGWNDLPL--KVREkKPARAKPVSVAPMvn 964  Kazachstania naganishii CBS 8797
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