2JUF


Conserved Protein Domain Family
Cul7

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pfam11515: Cul7 
Mouse development and cellular proliferation protein Cullin-7
The Cullin Ring Ligase family member, Cul7, is required for normal mouse development and cellular proliferation. Cul7 has a CPH domain which is a p53 interaction domain. The CPH domain interaction surface of P53 is present in the tetramerisation domain.
Statistics
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PSSM-Id: 402903
View PSSM: pfam11515
Aligned: 19 rows
Threshold Bit Score: 127.406
Threshold Setting Gi: 163773292
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2JUF_A          5 RSEFSSRGGYGEYVQQTLQPGMRVRMLDDYEEISAGDEGEFRQSNNG-I---PPVQVFWQSTGRTYWVHWHMLEILGPE 79  
Q17IM6       2554 REDFKSADQYAMYVRGLICPGMLVRCCQDFEEIRKGDIGTVLKVEPE-GlhdLNVRVDWQMHDRPYWMCFVHLELLEAP 2631 yellow fever m...
XP_002025047 1465 RKDFQTADHYALYVRGLVRPGMTVRCCRDFEEIKQGDMGTVLIVDTE-GlhdLNVQVDWRNHGSTYWVCFVHIELVEPP 1542 Drosophila per...
OXU31335     1384 RSDFLSVDEYAIYVRDNVKSGMLVRCCKTYEEVEYGDVGQVVKIDPE-GlhdLNVQVSWQHKGGTYWVRFIHIELLGHP 1461 Trichomalopsis...
XP_002427731 2579 RSDFLSNDEYALYIRDNIALGMIVRCCKTYEEVHEGDIGRVLKIDRE-ElhdLNVRVDWQQKGSPYWVRFIHIELVGFP 2656 human body louse
XP_001629259 2017 RSDFSSNDEYARYVRDHIQTGMMVRCCRTYEEVHEGDIGRVIKLDRD-GlhdLNVQADWQRKGGTYWVRYSHVELLGHD 2094 starlet sea an...
XP_008103129  369 RSAFPSRNCYMEYLKEKLVHGMRVRMLESYEKVSAGDEGEFLQSNNGt----PPLQVYWESLGRTYWVHWHMVEIVDSs 443  green anole
XP_001946768 2309 RNDFDSADGYANYVKYAVDVGMIVRCCREYESINVGCEGKVIKIMRDgGlhdLNIKVDWKSIGIVYWVRYIHIELIDYG 2387 pea aphid
XP_017945585  362 PHDFPSRNAYVDYIQENLKPGMTVKMLEDYDEISTGDEGIFRQSNNGm----PPVQVLWSSTGRTYWVHWHMVQIIGSG 436  tropical clawe...
XP_018672770 2431 PHDFNDNDDYARYVRDNITIGMMVCCCRTYEEVEEGDIGQVLRLDKD-GiqdLNVQASWINKGGTYWVRYIHVELIASP 2508 vase tunicate
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