Conserved Protein Domain Family
BCL9
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pfam11502: BCL9 (This model is not part of the current CDD release)
B-cell lymphoma 9 protein
The Wnt pathway plays a role in embryonic development, stem cell growth and tumorigenesis. BCL9 associates with beta-catenin and Tcf in the nucleus when the Wnt pathway is stimulated leading to the transactivation of Wnt target genes.
Links
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Statistics
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PSSM-Id: 519741
Aligned: 9 rows
Threshold Bit Score: 35.8691
Created: 15-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
XP_973551     298 NLTPQQRQHREEQLATIRKMQQMLFPENQAMDGQPPPGN 336 
XP_046865115  569 NLTPQQRQHREEQLAKLKKMNQFLFPEHDSGVGGQMIGM 607 
EDX15203      446 NLTPQQRQHREEQLAKIKKMNQFLFPENENSVGANVSSQ 484 
XP_005171039  502 GLSQEQLEHRERSLQTLRDIQRMLFPDDKDMAAMGQGNM 540 
XP_003212777  385 GLSKEQLEHRERSLQTLRDIERLLLRSGEAEPFMKSSQS 423 
XP_023817397  350 GLSKEQLEHRERSLQTLRDIERLFLRSGTAGGPGDAGGP 388 
EFN68427      313 NLTPRQRQHREVQLATLRKMQLMLFKDEQSGNALADTTQ 351 
1_pfamImport    1 NLTPQQRQHREEQQATLRKLQLVLFPENSNSGGGPSQQQ 39  
XP_029690552  481 GLSQEQLEHRQRSLQTLRDIQRMLFPDDRDAPPPGPPQs 519  torafugu
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