Hinp1I is a type II restriction endonuclease, recognising and cleaving a palindromic tetranucleotide sequence (G/CGC) resulting in 2 nt 5' overhanging ends. HINP1I has a conserved catalytic core domain containing an active site motif SDC18QXK and a DNA-binding domain.
Jiyao W et al.(2023). "The conserved domain database in 2023.",