1JPE,6DNV


Conserved Protein Domain Family
DsbD_N
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pfam11412: DsbD_N (This model is not part of the current CDD release)
Thiol:disulfide interchange protein DsbD, N-terminal
This entry represents the N-terminal domain of DsbD, a transmembrane electron transporter. DsbD binds to a DsbC dimer and selectively activates it using electrons from the cytoplasm. The N-terminal domain of DsbD (DsbDN) is capable of forming disulfides with oxidized DsbC, DsbE, or DsbG as well as with reduced DsbD.
Links
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Statistics
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PSSM-Id: 519701
Aligned: 79 rows
Threshold Bit Score: 59.6717
Created: 15-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
1JPE_A         27 RSQFVPADQA-FAFDFQQNQHDLNLTWQIKDGYYLYRKQI--RI-----T---PEHAKIADVQLPQGVWHEDEFygKSEI 95  Escherichia coli
WP_011746784   25 SAELLPGWTT------SQGHRMTALHLRLEPGWKTYWRSPgdAGvpprfDwggSQNLGEVRLMWPRPEVIESGGe-RTLG 97  Paracoccus den...
WP_012179743   37 QVDVLPGWRE------ADGSHFAGIRIRMQPGWKTYWRTPgdGGipplfDlaaSGNLAGFTPRLPAPVVFDVDGl-RSIG 109 Dinoroseobacter
WP_012090855   34 RVRVIIED-N-SPNNATSNERRGALQVELQPGWKTYWRNPgdAGvppqiNiegEAK---AQIDFPAPVRFGGEDe-GGIG 107 Brucella/Ochro...
Q92KJ9         73 DFRIVASQPK------PHGAIPAILEVRLNPGWKTYWRDPgaSGippqvTldpSGGVSLQSIRFPVPKTFGEGPg-RYTG 145 Sinorhizobium ...
WP_015915183   46 RMRVIVLPPA------PDGTRQAGLQIEPNDGWFTYWREPgdSGippqlTaapEAKVTPSPLSFPVPKRMDIGSv-RDVG 118 Rhizobium/Agro...
tigr:AHA_3742  61 KVRLQADRS-------APDHTRILLEVALESGWKTYWRSPgeGGiapqiLwdqPVG--DFQWHWPTPRPFEVAGl-STQG 130
Q5QZ90         42 SVKLELTGHYeA----ERNLLPALLHVELDEGWKTYWRSPgeGGipptfDwakSANINDIEWHWPVPSRYSIQGi-DTVG 116 Idiomarina loi...
Q5E1V7         46 ETRFVLTGQInK----VDQTVAGFLEVRLAGDWKTYWRSPgeGGiapsmTwedSQNIRSIDWYWPYPKRFDLLGi-ETLG 120 Aliivibrio fis...
ABM05290       69 SVLAELTGQIdKDK--DKQSVNALLQVRLAGEWKTYWRSPgeGGvapsfDfsnSTNIKEVNWLWPAPKRYPVSGv-ETIG 145

1JPE_A         96 YRDRLTLPVTINQAS----AGATLTVTYQGCADagFCYPPETKTVPLS 139 Escherichia coli
WP_011746784   98 YHDELVLPIEIAPAShaapVEPRAVVDFGICQD--ICVPVRVELQAGP 143 Paracoccus denitrificans
WP_012179743  110 YVDEVVFPLQLQTVQgdapIQLDGALHFGVCEE--VCVPVEVRLKAEL 155 Dinoroseobacter
WP_012090855  108 YKQPVSLPIVFHLTAad--trLKGHVFLGVCEK--ICIPVQATFDFPL 151 Brucella/Ochrobactrum group
Q92KJ9        146 YDVPVAFPLTLKRTGnggdVTIRASVFLGICED--ICIPVQGDVTVAL 191 Sinorhizobium meliloti
WP_015915183  119 YDHAVVFPFTLKSSGedwqSPLKLTAFIGMCRN--ICIPFQAELSIDL 164 Rhizobium/Agrobacterium group
tigr:AHA_3742 131 YQQQVRFPLSLDYPAg---QPLKGTLRLSTCSN--VCILTDYPFTLAV 173
Q5QZ90        117 YQGSLTFPLMVQLSPdarqANISGTLTMSSCTT--VCVLTDYPIDLHV 162 Idiomarina loihiensis
Q5E1V7        121 YKGSVIFPMTLHIDDlnkpVTFKADLTLSSCTT--ICVLTDYPFELTF 166 Aliivibrio fischeri ES114
ABM05290      146 YKGQVNFPLTIVLQDmgqpARLKGILTLASCTN--ICVLGDYEIDLTF 191
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