Conserved Protein Domain Family
SARA
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pfam11409: SARA 
Smad anchor for receptor activation (SARA)
Smad proteins mediate transforming growth factor-beta (TGF-beta) signaling from the transmembrane serine-threonine receptor kinases to the nucleus. SARA recruits Smad2 to the TGF-beta receptors for phosphorylation.
Links
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Statistics
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PSSM-Id: 491850
Aligned: 6 rows
Threshold Bit Score: 40.7011
Created: 15-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
XP_005155592  712 SPNPNIPSEYCSTIPPMQQARAAgtLNSPPPTVMVPVSV 750 
XP_002428675  132 RPNPNNPMEYCSTVPPPLQINSS--GSQPPPSVMVPVGV 168 
1_pfamImport    1 HPNPNNPMEYCSTVPPLQQVTDS--KNQPVPSVLVPVSV 37  
3_pfamImport    1 QPNPNNPMEYCSTIPPLQQAAST--INQPPPSVLVPTGV 37  
Q7QH71        152 QPNPNNPMEYCSVIPPLQQAAASnqPQSPI-SVMVPVGV 189  Anopheles gambiae str. PEST
2_pfamImport    1 SPNPNNPMEYCSTLSPYQQVEIEnnAKTQM-EVMVPVSV 38
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