Conserved Protein Domain Family
Zn_ribbon_12
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pfam11331: Zn_ribbon_12 (This model is not part of the current CDD release)
EDR4 zinc-ribbon domain
This zinc beta ribbon domain is found in Protein ENHANCED DISEASE RESISTANCE 4 (EDR4) and related plant proteins. EDR4 mainly localizes to the plasma membrane and endosomal compartments. It plays a negative role in resistance to powdery mildew and this requires salicylic acid signaling. In Arabidopsis, EDR4 associates with CLATHRIN HEAVY CHAIN2 (CHC2) and modulates plant immunity by regulating the relocation of EDR1.
Links
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Statistics
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PSSM-Id: 519679
Aligned: 28 rows
Threshold Bit Score: 57.9821
Created: 15-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
XP_009119692  218 AGGAPFVACHNCFELLYLP-RKKLLLSQakQQQKLQCGACSEVFSFTI 264 
XP_002441266  318 mGGAPFLVCGSCSELLQAPaTTGLP-RE--KVVRLRCGGCEEVLEMta 362 
XP_004970382  339 LGGTPFVVCDECKEILQLPaALPVG-----RASRLKCGGCGEAFELTL 381 
XP_006646435  341 LGGTPFVVCDKCSEILQLPaAVAVD-----RTARLECGACGHVLSIKL 383 
XP_006575382  857 AGGAPFVTCHKCLKLLQLP-ADFLLFKR--VYHQLKCGACQEVLKFSL 901 
EEF41595      665 AGGVPLITCPCCLKQLQLP-ADFVLFKR--RFHRLKCGACSEVLKFSL 709 
EFH47402      470 AGGAPFVSCYSCSENLQLP-VDFLIFKR--KHHLLRCGTCTSVLRFSL 514 
XP_010658164 1005 AGGAPFLTCYHCSHLLQLP-ADFLLFKR--RCHGLRCGACYELLKFSV 1049
CAL9046222    185 LGGAPFVVCYNCLQLLLLP-LDFFIARR--RLCKLQCGACSKVLMFSF 229 
XP_006842534  569 ASGAPFVTCYKCLRLLQLP-ENFHVSRK--KHYKLKCGACSRVLSFSL 613
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