Conserved Protein Domain Family
IRF-2BP1_2

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pfam11261: IRF-2BP1_2 (This model is not part of the current CDD release)
Interferon regulatory factor 2-binding protein zinc finger
IRF-2BP1 and IRF-2BP2 are nuclear transcriptional repressor proteins and can inhibit both enhancer-activated and basal transcription. They both contain N-terminal zinc finger represented in this family and C-terminal RING finger domains.
Statistics
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PSSM-Id: 519654
Aligned: 4 rows
Threshold Bit Score: 107.997
Created: 15-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_003385563  21 RTKCFLCEVPRGPWAMIYDFHEPVCRACCNYEGIDRIAEVVDKARHLRRS 70 
XP_002647633  85 RQQCYLCDLPRWPWAIINEYIEPVCRGCVNYEGSDRIELVLEEARQQKKL 134
XP_003976639  11 rqWCYLCDLPKMPWAMLWDFSEAVCRGCVNYDGADRIELLIDTARQLKFT 60  torafugu
XP_056707519  11 RQSCYLCDLPRMPWAMIWDFSEPVCRGCVNYEGADRIEFVIETARQLKRA 60  tarantolino
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