Conserved Protein Domain Family
EccE

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pfam11203: EccE 
Putative type VII ESX secretion system translocon, EccE
EccE is a family of largely Gram-positive bacterial transmembrane componenets of the type VII secretion system characterized in Mycobacterium tuberculosis, systems ESX1-5. Translocation of virulent peptides through the membranes is thought to be mediated via a complex that includes EccB, EccC, EccD, EccE, and MycP. EccB, EccC, EccD, and EccE form a stable complex in the mycobacterial cell envelope.
Statistics
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PSSM-Id: 402675
View PSSM: pfam11203
Aligned: 49 rows
Threshold Bit Score: 51.1466
Threshold Setting Gi: 568233779
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
BAJ31095      249 TPALRLTWVALKLDPERAATAVLARGGGEEGARKTLQRVTDQLAGRLNSAGFTATVLDE-RELIAALAISVCANPVAVAg 327 Kitasatospora ...
A0QNL0        179 APANRRTWIVLRADPEKTQRSAHRRDSGVSGLARYLVASATRIADQLASNGVDARCCRSfDDYEKATEISYE-------- 250 Mycolicibacter...
P9WJE9        177 APANRRTWIVLRADPERTRKSAQRRDEGVAGLARYLVASATRIADRLASHGVDAVCGRSfDDYDHATDIGFV-------- 248 Mycobacterium ...
WP_010907483  177 APAHRRTWIMLRADPVRTRKSAQRRDAGVAGLARYLIASTTRIADQLASHGVDAVCGHSfESVDHATDVGFM-------- 248 Mycobacterium ...
jgi:Mvan_0091 180 APASRRTWIVLRADPDKTRKSALRRNEGVAGLAQYLVSSTTRIADHLASKGVDARPARSfDDFDRATEISFE-------- 251 Mycolicibacter...
jgi:Srot_0750 137 vgdeqEAWITLVVDAVQNLVALRAR-SPRIQLHELAEATGRRLAAQLREEGFSSSSGRD-PQAEHADDAQHREGSPAPSp 214 Segniliparus r...
P9WJE5        126 ASGDCRTWVGLTVVADDNLAALQAR-SARIPLQETAQVAARRLADHLREIGWEAGTAAP-DEIPALVAADS--------- 194 Mycobacterium ...
B2HSU8        197 AANRRRTWLILRMNPQRNVAAIASR----DSLASTLVTATERLAQVLDGQSCAARPLAA-DELAEVDSAILAELEPTWS- 270 Mycobacterium ...
Q9CBV4        196 T-YQRCTWLVLRMNPQHNVVAVAAR----DSLASTLVAATERLAQDLDGQNCAARPLAA-GELAEVDSAVLADLEPTWS- 268 Mycobacterium ...
Q73ZT9        198 TSYIRRTWLVLRMNPQRNVAAVAAR----DSLASTLVAATERLAQDLDGLTCAARPLTA-EEIAEVDRAVLADLEPTWS- 271 Mycobacterium ...
BAJ31095      328 rqgsggggvgvrrtQESAKYCRIDD-R 353 Kitasatospora setae KM-6054
A0QNL0        251 --------------RETWSSIKGRS-T 262 Mycolicibacterium smegmatis MC2 155
P9WJE9        249 --------------REKWSMIKGRD-A 260 Mycobacterium tuberculosis H37Rv
WP_010907483  249 --------------QEKWSMMRGQN-A 260 Mycobacterium leprae
jgi:Mvan_0091 252 --------------RETWSMVKGRS-T 263 Mycolicibacterium vanbaalenii PYR-1
jgi:Srot_0750 215 idgl-----raddgAEDWNGVVVGE-E 235 Segniliparus rotundus DSM 44985
P9WJE5        195 --------------RETWRGMRHTDsD 207 Mycobacterium tuberculosis H37Rv
B2HSU8        271 --------------RPGWRHLKHFN-G 282 Mycobacterium marinum M
Q9CBV4        269 --------------YPGWRHIKYVN-G 280 Mycobacterium leprae
Q73ZT9        272 --------------RPGWRRLKHFN-G 283 Mycobacterium avium subsp. paratuberculosis
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