pfam10980: DUF2787 (This model is not part of the current CDD release)
Protein of unknown function (DUF2787)
This bacterial family of proteins has no known function. The conserved hypothetical protein VC1805 from Vibrio cholerae belongs to this group. It adopts a monomeric assembly, showing an unusual topology with a flat seven-stranded anti-parallel beta-sheet and two helices located on the same side of the sheet. It has some structural homology with the human protein p32 and binds to the complement protein C1q, which suggests a possible role in the adherence of the bacteria to the intestinal wall.
Jiyao W et al.(2023). "The conserved domain database in 2023.",