Conserved Protein Domain Family
YhfG

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pfam10832: YhfG 
YhfG
This protein family includes proteins predominantly found in Gammaproteobacteria, such as YhfG from Escherichia coli. YhfG is a FicA antitoxin homologue (also known as antitoxin EcFicA) that interacts with EcFiT and forms a complex with it. YhfG shows a unique conformation, forming two parallel alpha- helices linked by a 10-residues loop. The structure of the complex shows a highly conserved extended ligand-binding pocket.
Statistics
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PSSM-Id: 491452
Aligned: 20 rows
Threshold Bit Score: 45.0427
Created: 15-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_047873463   5 TALTETQKQQRFKQLQSRNYKASMRLEGIHwvetLPNLDRIVLTEAEKIAELTLHYAR 62  Photobacterium aphoticum
WP_093070224 188 APSPDERKQRYYQATRNHNYRASLRLEGLSl--pDDIAALPLPTTAQGMATLIQQTKD 243 Thiothrix caldifontis
WP_004898474   1 MLVTTEQKKKYIQATRLKNYQASLKLEGLK---------SSTTSEALTKTQILQKYQQ 49  Acinetobacter brisouii
WP_139171626   2 PNVSLKAKQAYFAKVKRANYAASLRLEGVN--------MVSSPQPMGSKAAVLKRYRQ 51  Modicisalibacter muralis
WP_016417046   2 THVSLKTKQAYFTKVKRANYAASMRLEGFS--------VTSESYPTASKAAILEKYRR 51  Litchfieldella anticariensis
WP_097085389   1 MPTSLETKRAYFAKVRRINYAASLRLEGFN------VPQGEEEKPVPTREQVLRRYRT 52  unclassified Pseudomonas
WP_087515879   2 PAASLKAKKAYYAKARQSNYVASLRLEGFQ------VTRADAVRKLPTRESVLSAYRN 53  Pseudomonas sp. M30-35
WP_139053052   2 SNLSLQTKKAYYAKVRQSNYAASLRLEGFD------VVPADAERKPPSREAVLRAYRA 53  Pseudomonas saudiphocaensis
WP_128576036   2 PDLTLEEKKTYYAKVRQSNYAASLRLEGFD------TTPADAKRKLPTREAALRALRA 53  Pseudomonas sp. BAY1663
WP_016492332   2 PAPSLQAKKAYFAKVRQSNYAASLRLEGFD------VTPADADRKLPTCEAALDAYRN 53  Metapseudomonas resinovorans
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