Conserved Protein Domain Family
Sfi1_C

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pfam10638: Sfi1_C 
Spindle body associated protein C-terminus
This C-terminal domain of spindle-body-associated protein Sfi1 has an important role to play in the bridge-splitting during bi-polar spindle assembly, and this separation event possibly requires interaction with integral components of the nuclear envelope, such as the Mps2-Bbp1 complex. Centrally to this domain is a region carrying centrin-binding repeats with repeating units containing tryptophan, family Sfi1_central, pfam08457.
Statistics
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PSSM-Id: 402327
View PSSM: pfam10638
Aligned: 8 rows
Threshold Bit Score: 158.33
Threshold Setting Gi: 156117574
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
CAR26457      853 FEVKTPIKKLSPKgSNTIPGSEGVKMHRIEAMKSHYSRVRRAIPSPVKSSLSLNSTAKKKIENEEDNVFFSSKqkqqqqn 932  Zygosaccharom...
CAR21486      829 QSLVTPTRIKKSG-NITIPGSERMKQNRMEAMRNHYRRARKAIPSPIKFSDNLDTITKKRLEIGDRESSEPSP------- 900  Lachancea the...
Q6CK76        825 LTFQTPMKSPNNA-AVTIPGSTRVKRNKMDRIRNRFSRARGAIPSPIKTTNVLDSTVKARLSDQRNTAAKDTTg------ 897  Kluyveromyces...
Q75F87        841 HDFMTPLKADK----VTIPGSERVKKNKMERIKNRYRGARRAIPSPIKSSDILDSTTKRKLSKIGKIQTPLQNayvdd-- 914  Eremothecium ...
XP_003648376  834 SGFMTPLKLDR----ITIPGSERMMKNKMERIKNRYRGARRAIPSPIKSSNVLGSSIKRKLSTMVNTNQPHDDayedd-- 907  Eremothecium ...
CCE92657      819 MELVTPVRRNVPR-KNTIPGSEGVKRYRLEAMKSHYGRVRRAIPSPVKSSATLNSTAKRKIESEQESTAWSPKpl----- 892  Torulaspora d...
XP_003685824  801 DRLETPKKSINTS-GNTIPGSELVKNYKVEAMKSRYSRVRHSIPSPIKNSSTIGSTIKRRFNQRNLNVSPFPAs------ 873  Tetrapisispor...
EDO19035      806 AHLVTPMRDPPFAeSQTIPGSELIKNYRIEAVKFRYSRAKRLVPSPIKSSVSLGSSVKEKLQVSAASYINERIs------ 879  Vanderwaltozy...
CAR26457      933 qrlppPPRLSLERINKNLASKIDRINFERIPE 964  Zygosaccharomyces rouxii
CAR21486      901 -----PPKLDLGKINKKLASRHTKISFKTIPE 927  Lachancea thermotolerans CBS 6340
Q6CK76        898 -----AQATYLLSVNKRLAGKTRNISFNKIPE 924  Kluyveromyces lactis
Q75F87        915 pnttpIPKLKLEQEGRRYSLRVRNIDFNRIPE 946  Eremothecium gossypii
XP_003648376  908 htmtpVPKLNILQEGKKYNSSVKNLDFSRIPE 939  Eremothecium cymbalariae DBVPG#7215
CCE92657      893 ----fPPRLSLERINKNLASKIDTINFERIPE 920  Torulaspora delbrueckii
XP_003685824  874 -----PPKLNLYRRYNISDNKNLEIDFNELPy 900  Tetrapisispora phaffii CBS 4417
EDO19035      880 -----PPRLAIEKINKNLASKVHEIRFDKIPN 906  Vanderwaltozyma polyspora DSM 70294
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