8SNB,8J07,8I7O


Conserved Protein Domain Family
CMI2B-like
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pfam10629: CMI2B-like (This model is not part of the current CDD release)
Ciliary microtubule inner protein 2B-like
This family represents a domain found in human Ciliary microtubule inner protein 2B (CMI2B) and similar proteins from eukaryotes. CMI2B is a microtubule inner proteins (MIP) that form part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating. This domain is a tubulin-binding domain. Some proteins contain multiple copies of this domain.
Links
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Statistics
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PSSM-Id: 519483
Aligned: 27 rows
Threshold Bit Score: 58.563
Created: 15-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
8SNB_1P       18 PPRLMPGYKGHCPTMKFDYGE--TYGNATAKCLQDYRSTTLNNSKTNYS-NGGQ----FPTVYTHNPDQVIGAR 84  purple sea urchin
XP_009015125  18 HPRFMPGYKGYVPTMKYEHGE--TYGNQTNKCFQDFRSKTFETSRTLSN-RGGY----FATRFTSNPDLACEAR 84 
EDO32645      16 DLRHLPGYAGFRPQQQWRYGD--TFGNDTAKYFQDKRTAQLKRSTAQAPgTEWDakiaFPTVYSNDPKLVVGAR 87 
XP_001987465   8 EPHLVPGYTGHCPENRDRVGS--TYGKQTHKLLID------------------------PCS-NHAPELIVAPI 54 
XP_001623010  46 DPYHIPGYCGYCPQFKYQIGE--TFGRTTSCLLTD------------------------NSV-AYSGKPVLSDI 92 
XP_003794849  13 EPHYIPGYAGFYPQLRYQVGN--TYGRTTAQLLTD------------------------PSV-RKSPCSVLSPM 59 
EDO44167      16 HPRHMPGYLGYTPTIKYTYSD--TYGNTTAKWFSDYRNATINTSKERMW-RGGHkhlpFPTYYTGNPDHVLGAR 86 
EDO49197     111 DPKNMPANRYYTPSLYTSFGDipSHGAGREKWFHDYRRSNIAERTLRNGqLSMNpppiRPTSFSDNPDRVLGKR 184
XP_026690420  21 EPYHVPGYAGYRPQFKYQCSE--TFGNSTHRLLTS------------------------PHV-RKSSNTVLVPI 67  vase tunicate
XP_002130039  19 PPSIMPGYRGYVPNLMYKYGD--TYGNATLKYFQDFRSATLNTSRSPYSaKGGE----FPTIYTYDPSLVLGNR 86  vase tunicate
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