8GDW,5BNC,6M09,2ARZ


Conserved Protein Domain Family
DUF2470

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pfam10615: DUF2470 (This model is not part of the current CDD release)
Domain of unknown function (DUF2470)
This domain is found in a group of putative heme-iron utilisation proteins, such as HugZ. It can also be found in C-terminal of the glutamyl-tRNA reductase-binding (GluTRBP) protein from Arabidopsis. GluTRBP is involved in the regulation of glutamyl-tRNA reductase (GluTR) which is important for the synthesis and distribution of 5-aminolevulinate, a precursor in heme and chlorophyll biosynthesis. GluTRBP is necessary for efficient photosynthetic electron transport in chloroplasts.
Statistics
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PSSM-Id: 519478
Aligned: 174 rows
Threshold Bit Score: 48.8117
Created: 15-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
8GDW_AAA      10 SDRICKHMNEDHASAIALYAQVFGQQTDvTMAQ--MQAIDPTGMDL-V----VESEggSKTIRIEFEQPLKDSEDAHQVL 82  Synechocystis s...
WP_013578576 183 GPGIIAHMNADHVDSMILLARTH-SGYEaTEAT--MTSVDRLGFFLrLk---TAEG--YKGTRINFLQEVHTAQDTRKIL 254 Granulicella tu...
WP_014265437 183 APRILGHMNADHISAMILLAKVH-AELYaTEAT--MTAVDRLGFHLrLk---TAEG--MKGTRINFLREVQTADETRKVL 254 Granulicella ma...
WP_012590409 175 EQGALAHMNADHADALALYAAAFTGK---SGADwvATGLDPEGLDLm------RGD--EA-ARIVFPRRAQTPGELRAVL 242 Methylocella si...
Q89BK5       165 EEGAVEHMNADHRDAMGLYATRLLGA---AAGDwrCTGCDPEGLDMq-------DG--QTALRLDFPERVTSGTALRKML 232 Bradyrhizobium ...
WP_012564699 166 EEEIVAHLNTDHPETLSLFATQLLDT---PAADwrCIACDPDGLDLa------AED--RY-LRLTFPRRVASPGALRTVL 233 Afipia carboxid...
Q1QR13       166 EQSAIDHMNADHRDALNLYATQLLGA---ETADwrCTGCDPDGLDIs------ADK--HSALRLDFPRRIVAPAELRVVL 234 Nitrobacter ham...
WP_332118494 161 VEGVVSHMNEDHADAIALYATRLLGEPErEGVAwrMIGLDPDGCDLa------DGD--VV-RRLDFPQRVTGRGAVRQVL 231 Azorhizobium ca...
WP_015931884 175 EAGAVAHMNEDHADALALYAVHFAGA---EPGPwrLTGLDPEGLDLl------AGD--RT-ARVIFPNRLSSPGTLRQVL 242 Methylobacteriu...
WP_015831688 161 EAHILDHMNTDHADSLIAYCRHVHGV-EaTQAS--MLGIDCDGFDVaAtvnnQ-----SMTLRFVFATPIHDAQSARAAL 232 Methylotenera m...
8GDW_AAA      83 IAM 85  Synechocystis sp. PCC 6803
WP_013578576 255 VEM 257 Granulicella tundricola
WP_014265437 255 VEM 257 Granulicella mallensis
WP_012590409 243 VEL 245 Methylocella silvestris
Q89BK5       233 VRL 235 Bradyrhizobium japonicum
WP_012564699 234 KDL 236 Afipia carboxidovorans
Q1QR13       235 KEL 237 Nitrobacter hamburgensis X14
WP_332118494 232 VQL 234 Azorhizobium caulinodans
WP_015931884 243 VEM 245 Methylobacterium nodulans
WP_015831688 233 VSL 235 Methylotenera mobilis
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