Conserved Protein Domain Family
Tom37

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pfam10568: Tom37 
Outer mitochondrial membrane transport complex protein
The TOM37 protein is one of the outer membrane proteins that make up the TOM complex for guiding cytosolic mitochondrial beta-barrel proteins from the cytosol across the outer mitochondrial membrane into the intra-membrane space. In conjunction with TOM70 it guides peptides without an MTS into TOM40, the protein that forms the passage through the outer membrane. It has homology with Metaxin-1, also part of the outer mitochondrial membrane beta-barrel protein transport complex.
Statistics
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PSSM-Id: 402277
View PSSM: pfam10568
Aligned: 146 rows
Threshold Bit Score: 86.149
Threshold Setting Gi: 307104527
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
KLU82632           22 CLAAIAYLK-YVAgpgdYELVATS-PSA-VPTNHLPAVHN------TLs---gEWA-SG---------FQGVLGLIHAAt 79  Magnaporth...
EFP04303           15 CLAVQTFLRmTSLp---FNVRQRPnVDFiSPDGVIPLLKIn------------KTLiTG---------FNAIVDFVH--- 67  Caenorhabd...
EJW85800           44 CVAVQTLLKmANLp---VRLEERPnAEFmSPTGKVPFLKLq------------SFLvSE---------FLPVVDFLA--- 96  Wuchereria...
EXX56090           64 CVKWQTFLKfSKSd---FETKRSNePLM-SPSGKLPFLILttgdvlVD---------------------DSIEKHVTDMy 118 Rhizophagu...
EIE85724           65 CLQIQAYLKfCGIe---YDIYPINqPEA-SPSGKLPFLATvvgevyDE---------------------HQIIHWVKETr 119 Rhizopus d...
EPB88021           66 CLIIQMYLKfCGId---FDVNNINePAA-SPSGRLPFLATvsgsiyND---------------------QETINWVKETr 120 Mucor circ...
EGF77570           53 CLKYQTYLKfAKYp---HTIKEHTeHSF-SPSGKLPALLTssgrllSG---------------------CEIISEVKSKn 107 Batrachoch...
WP_011995021       21 CVKLETALRlAGVp---HRVWYNTnPAN-GPKGKLPFIEI------ED-----QRI-GD---------SALILYHLKERl 75  Parvibacul...
WP_012163069       20 CMKLETYFRmTGLe---YQVDTSAdVRK-APKGKLPYIED------KG-----QII-AD---------SNLIIEYLKTTy 74  Acaryochlo...
jgi:MICPUN_108538  27 CIAVETYLRlAGLr---FAVEDCRtHYA-SPSGALPALDQ------NLdvvggAVPgDTnrdptgalaRHRIVEHLRRK- 95  Micromonas...
KLU82632           80 tttetggrgpraghrwpSLDSR-L-----NLPPAAVADSTAHCVFLTAHAAPLLALSLYVSSANWSGATRPAISQVLPFP 153 Magnaporth...
EFP04303           68 ---------------------KkGvtltsHLSETQVADMRANISMIEHLLTTVEMFVLWKHDETYDKVTKLRYGSVYHWP 126 Caenorhabd...
EJW85800           97 ---------------------KrNvklsaGLTDLERGDMHAHMALFDDILKNVEMYVMWMDKRNYSQVTKCRYGSVYLFP 155 Wuchereria...
EXX56090          119 s--------------dnLG----------RINEQQEADSQSFIALADTKLRNALLYNLWCEPAN-ESITYKKYVGHYAKP 173 Rhizophagu...
EIE85724          120 ----------------kME----------KELSSDIEQSKAFITLVEKKLKPALLFSMWLEPLNANEITCKAYYDHLPAP 173 Rhizopus d...
EPB88021          121 n--------------leKQ----------LTDDKDREQAKAFTTLVETKLKAALLFSMWLEPLNANQTTYKSYYGHTPTP 176 Mucor circ...
EGF77570          108 g---------------lES----------NASAEDKAKMDAFDSLIESHLSFGLDYELWYESSHFENIIAPIIGAYYPWP 162 Batrachoch...
WP_011995021       76 -----------------GVDLD-R-----SLSDGERAQSHMLHQMLDERLYWVLLHSRWMDEANWRVTRQCYFG-GLPFP 131 Parvibacul...
WP_012163069       75 -----------------GDPLD-S-----HLSPADAAIALAMRRLIEENLYWALVYTRWIDEENWQKTKAVYFS-DLPFP 130 Acaryochlo...
jgi:MICPUN_108538  96 -----------------VRDVD-A-----HLGPDDRAQLAAYVALVEHKLATTTAWYQWIDKDRFAKHTRLAYGAAFPAP 152 Micromonas...
KLU82632          154 LGWSEGPARR 163 Magnaporthiopsis poae ATCC 64411
EFP04303          127 LSSVLPFLKR 136 Caenorhabditis remanei
EJW85800          156 LNIILPQVKW 165 Wuchereria bancrofti
EXX56090          174 LDKLLFQKYK 183 Rhizophagus irregularis DAOM 197198w
EIE85724          174 VNHAVFYKKQ 183 Rhizopus delemar RA 99-880
EPB88021          177 VNMIVSYNKQ 186 Mucor circinelloides f. circinelloides 1006PhL
EGF77570          163 LNFILPRIQR 172 Batrachochytrium dendrobatidis JAM81
WP_011995021      132 LSLIVPRMAR 141 Parvibaculum lavamentivorans
WP_012163069      131 LRLLVPKIAR 140 Acaryochloris marina
jgi:MICPUN_108538 153 LSHVLPWMWR 162 Micromonas commoda
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