Conserved Protein Domain Family
CdCA1

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pfam10563: CdCA1 
Cadmium carbonic anhydrase repeat
This domain is the cadmium carbonic anhydrase repeat unit of the beta-carbonic anhydrase of a marine diatom, that uses both zinc and cadmium for catalysis of the reversible hydration of carbon dioxide for use in inorganic carbon acquisition for photosynthesis (thus being a cambialistic enzyme). Compared with alpha- and gamma-carbonic anhydrases that use three histidines to coordinate the zinc-atom, this beta-carbonic anhydrase has two cysteines and one histidine, and rapidly binds cadmium.
Statistics
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PSSM-Id: 402272
View PSSM: pfam10563
Aligned: 48 rows
Threshold Bit Score: 184.755
Threshold Setting Gi: 224014694
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_002505440    112 EAGMCPVNVHWHLGAEHVStGEYDMahtaDTANGptqphadarlpagRKLlaaggTTYLGGRCTKYp----nLSTAQKS- 186 Micromonas c...
OAH06272         53 YRDMNLCNIHTHTFAEHKG-PGFSI----SANNG----------------------QTDGYRCNDTa----gLSQEELT- 100 Rhodobactera...
WP_060834854     59 ASQMNLCNIHTHTNAEHAG-PGFAL----GAGSG-------------T-H--------GGFRCNETa----rLTEKELK- 106 Rhodovulum s...
WP_083499778     74 ASSLNLCNIHTHTNAEHKG-PGFSI----YAGPG-------------D-H--------GGYMCNESy----dLTPAELE- 121 Tropicibacte...
WP_045978490     50 YNELNLCNIHFHKNAEHRA-AAFSV----TAHSS---------------------PANTGYQCQLSk----aLAEHEKK- 98  Pseudoaltero...
jgi:OSTLU_33276  81 VSLMTLANVHYHSPAEHRSqGEFST----PNASE------------------------SGFACDDAsdatgtARVVATNg 132 Ostreococcus...
OUS47149         14 VRGMVLVNVHFHAPAEHRSeGEYST----REVSE------------------------TGFSCDDAa----tLGSDGEA- 60  Ostreococcus...
XP_002297009     40 QSSMCPVNVHWHLGTEHYSaGEYDE-----FGTGpnsvn----nnlpQNQ-----QVRPGYRCRHFd----kSQPMFTN- 100 Thalassiosir...
XP_002287620     13 QSSMCPVNVHWHLGSEHYSyGEFDEngngPHGNVarpswa-nrdlatDGA-----AVADGFRCHHYd----eNDPKFTT- 81  Thalassiosir...
XP_002290576     30 LSSMCPVNVHWHVGTEHYSyGQFDEngdgPNGNIdrpswaaryltdaSAE-----EEQPGFRCHHYd----aSDSKFTT- 99  Thalassiosir...
XP_002505440    187 ------DYD-WKYCK----KMVVGETYEVHWPHsemgacNTKWQYQLPFYDGVLCrlgeeaypgkgkfglGTVGgveqpl 255 Micromonas c...
OAH06272        101 ------D---PTHGSgafqGVAPGDTIEVHWVY------SSCAVQPGQGLGSCLS---------------AACA------ 144 Rhodobactera...
WP_060834854    107 ------DPA-AGLGaf--hGAKPGDTIEVHWVF------SSCEVAPGKGLGSCMS---------------ESCQ------ 150 Rhodovulum s...
WP_083499778    122 ------DPA-HGHGgf--hGVKPGDTIEVHWVH------TSCEVGPGPGLGSCLS---------------SACA------ 165 Tropicibacte...
WP_045978490     99 ------PLL-TPACD----GLQSGDTIEVHWVY------SSARVSPGPGLGSCVS---------------TASA------ 140 Pseudoaltero...
jgi:OSTLU_33276 133 ddvsdaRYA-FSFCQ----DVAVGDTIELHWVYs----tGAARTGVSDGLSGAFA----------------TQN------ 181 Ostreococcus...
OUS47149         61 ------SNDaFVHCE----NVALGDTVELHWVYst---gGERGAEISDGLGSAFA----------------TQR------ 105 Ostreococcus...
XP_002297009    101 ------EYR-WEFCV----GMQVGETYEVHWPHsaagacGTPDQYQTPFYDGVFCnldeek----fstlsAQDV------ 159 Thalassiosir...
XP_002287620     82 ------KYD-WKHCH----GMEVGETYEVHWPHsaagacGTVNQYQTPFYDGVFCnlpmes----fttlgGQDI------ 140 Thalassiosir...
XP_002290576    100 ------EYD-WMHCH----SMEVGETYEVHWPHsavgacGTVDQYQTPFYDGVFCnlsles----fnalgEQDI------ 158 Thalassiosir...
XP_002505440    256 slQGQIGVQAQVFVVVNDENYYYPDLLRGMIVtNDGPGSNTVMGKEI---TAYTGSTTGTSRDn-TICSAYGpVTWHVDR 331 Micromonas c...
OAH06272        145 --NPQLRVEAQVFLLVNDPYALNFQTMVYDNTvIDARHQAKALPTHTgtpIVFAGSTTGPKYTa-KKCSPYQ-VTWSVRP 220 Rhodobactera...
WP_060834854    151 --NPQLRVEAQAFLLVNDHTALDFKDYIYRGTqVNGLHQPRALPAGTgtpVLYGGSTTGPRYNq-AICSPLQ-VTWSVRP 226 Rhodovulum s...
WP_083499778    166 --NPQLRVEAQVFLVVNDPNALNFMDYVYGGE-VNGLHQAKRIPSDTgtpVVFAGSTTGTTYSq-QICSPLQ-VTWSVRP 240 Tropicibacte...
WP_045978490    141 --NPDLRVEAQVFTLVNDTGALNFTEMTRIVQ-RHGRYQSNEIPHDSgepVRYLGSTTGPSYSq-HQCSPYQ-VSWSVRP 215 Pseudoaltero...
jgi:OSTLU_33276 182 --NPYVVVRAQVFKITNNPSD-DVADLFVSWN-----------TTLVsdaVRYVGSTTGDKYDnvDRCSPFL-VIWHVDR 246 Ostreococcus...
OUS47149        106 --NPLIVVRAQVFRVTNGGDGAYDDDAKSL---LSGWNASIVTDA-----LQYIGSTTGSKYDsiDKCSPYA-VTWHVDR 174 Ostreococcus...
XP_002297009    160 --ADAVGVQAQVFTVVNDERYFYPDLMRGFIK-DGEYGKDIAM---------YTGSTTGTTRSn-EVCSSYApITWQVDR 226 Thalassiosir...
XP_002287620    141 --ANAVGVHGQVFTIVNDESYFYPDMIRGMIV-EPEMNMGQDI-------AMYTGSTTGDSRSn-EMCSQYApITWQVDR 209 Thalassiosir...
XP_002290576    159 --ANAVGVQGQVFTVVNDESYFYPDMIRGMIV-DGEMGQNIAY---------YTGSTTGSSVSn-ELCSPYSpITWQVDR 225 Thalassiosir...
XP_002505440    332 KCHLISASS 340 Micromonas commoda
OAH06272        221 NCAKLNIAS 229 Rhodobacteraceae bacterium SB2
WP_060834854    227 DCARLDINS 235 Rhodovulum sulfidophilum
WP_083499778    241 RCARLDISS 249 Tropicibacter naphthalenivorans
WP_045978490    216 DCRKLDIHS 224 Pseudoalteromonas ruthenica
jgi:OSTLU_33276 247 ECHRVSARS 255 Ostreococcus lucimarinus CCE9901
OUS47149        175 KCHNISARK 183 Ostreococcus tauri
XP_002297009    227 KCHLISASS 235 Thalassiosira pseudonana CCMP1335
XP_002287620    210 KCHMISASS 218 Thalassiosira pseudonana CCMP1335
XP_002290576    226 ECHMISASS 234 Thalassiosira pseudonana CCMP1335
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