Conserved Protein Domain Family
Toxin_36

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pfam10550: Toxin_36 
Conantokin-G mollusc-toxin
The conantokins are a family of neuroactive peptides found in the venoms of fish-hunting cone snails. They possess a high content of gamma-carboxyglutamic acid (Gla) (4-5 residues), a non-standard amino-acid made by the post-translational modification of glutamate (Glu) residue. Conantokins are the only natural biochemically characterized peptides known to be N-methyl-D-aspartate (NMDA) receptor antagonists.
Statistics
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PSSM-Id: 402262
View PSSM: pfam10550
Aligned: 13 rows
Threshold Bit Score: 27.0888
Threshold Setting Gi: 476007113
Created: 11-May-2020
Updated: 6-Aug-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
P69745  81 GEEEVAKMAaELAREDAV 98  Conus lynceus
P0CG46  80 GDEEYSKFI-EREREAGR 96  Conus sulcatus
P0DKY9  80 ADEEYLKFI-EEQRKQGK 96  Conus rolani
P0C8D9  73 GEEEHSKYQ-ECLREIRV 89  Atlantic fish-hunting cone
P0C8E3  81 GEEEHSKYQ-ECLREIRV 97  Conus purpurascens
P0C8E1   1 DEPEYA----EAIREYQL 14  Conus parius
P0C8E0   1 GEDEYA----EGIREYQL 14  Conus parius
P17684   1 GEEEYQKML-ENLREAEV 17  tulip cone
P58806  81 GEEEVAKMAaELARENIA 98  Conus radiatus
P0DKZ0  79 GEEELAEKApEFARELAN 96  Conus rolani
P0DKZ1  79 GEEELSENAvEFARELAN 96  Conus rolani
P07231  81 GEEELQENQ-ELIREKSN 97  geography cone
P0C8E2   1 GEPEVAKWA-EGLREKAA 17  Conus parius
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