1PIE


Conserved Protein Domain Family
GalKase_gal_bdg
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pfam10509: GalKase_gal_bdg (This model is not part of the current CDD release)
Galactokinase galactose-binding signature
This is the highly conserved galactokinase signature sequence which appears to be present in all galactokinases irrespective of how many other ATP binding sites, etc that they carry. The function of this domain appears to be to bind galactose, and the domain is normally at the N-terminus of the enzymes, EC:2.7.1.6. This domain is associated with the families GHMP_kinases_C, pfam08544 and GHMP_kinases_N, pfam00288.
Links
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Statistics
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PSSM-Id: 519422
Aligned: 426 rows
Threshold Bit Score: 43.9856
Created: 15-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
1PIE_A         36 EKFAEVFGDtkE--VEYFFSPGRINLIGEHTDYNGGYVFPASITIGTTGLAR 85  Lactococcus lactis
16_pfamImport   1 QAYQEHFGVg---dIELFSAPGRCEIGGNHTDHNHGKVLAGSITLDTIAVAA 49 
WP_022424235   39 QSFMDYYGDq---dIMIFSVPGKCEIGGNHTDHQQGRVLASAIQLDSIGIVG 87  Catenibacterium sp. CAG:290
17_pfamImport   1 TSFVNQFGDg---dVQILSVPGRSEVGGNHTDHNHGRVLACAVDLDIIAVAG 49 
18_pfamImport   1 NAFAQLYGGg---dVQILSVPGRSEIGGNHTDHNHGRVLACAVDLDVIAVAR 49 
CDD02940       40 ASFEQLYGDr---dVAFFSVPGRTEIIGNHTDHNNGRVIAASVDIDIIAVAA 88 
CDC64510       39 CRFSDLYGN--NrdLSVFSVPGRSELSGNHTDHNHGRVIAASVDLDMIAVVS 88 
CDC75648       40 REFSSLFGA--DreVRLFSVPGRSEISGNHTDHNRGCVIAAAVDLDIIAVAS 89 
CDC94280       34 TKFKECFGEg---eVDFFSAPGRTEILGNHTDHNHGKVLTASIAMDTIAAAR 82 
WP_012200256   28 QQFMEHFNSe---qMEFFSAPGRTEIVGNHTDHNGGKILAASITLDTIGAAY 76  Lachnoclostridium phytofermentans
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