Conserved Protein Domain Family
Ribosomal_L50

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pfam10501: Ribosomal_L50 
Ribosomal subunit 39S
The 39S ribosomal protein appears to be a subunit of one of the larger mitochondrial 66S or 70S units. Under conditions of ethanol-stress in rats the larger subunit is largely dissociated into its smaller components. In E. coli, in the absence of the enzyme pseudouridine synthase (RluD) synthase, there is an accumulation of 50S and 30S subunits and the appearance of abnormal particles (62S and 39S), with concomitant loss of 70S ribosomes.
Statistics
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PSSM-Id: 402226
View PSSM: pfam10501
Aligned: 45 rows
Threshold Bit Score: 75.3908
Threshold Setting Gi: 927392805
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EDK45407      107 DKVQLQGIVQKVYKDVLILDLKasaktdkpkfsdftlvdeiltqvggVERFEQYGLE--NLDLRFELVKKLQSSLGIELN 184  Lodderomyces ...
XP_015788627  103 PREDVIECIKNIYMCYFTPKTEn------------------------DDDWLSQPLD--DMFTKFSFLSECDKQLEHEIP 156  two-spotted s...
Q22623         94 PGVDVKNQVLEAASSCLRSAGVk------------------------SENVDQYKFVegDNSVKFELLNRLGKSIEHWPT 149  Caenorhabditi...
1_pfamImport    3 PSNNVKDQVLETASTCL---GVk------------------------ADSVSQYKFAdgDNSLKFELLTRLGKSIKHWPT 55  
EFO86175       93 PSNEVKNQVLKTASECLQKAGIs------------------------SENVEQYKFVegDNSLKFELINRLGKSIKHWPT 148  Caenorhabditi...
XP_002631371   93 PSTGIKSQILETATECLQNAGVs------------------------SDNIEQYKFIdgDNSVKFELINRLGKSTKHWPT 148  Caenorhabditi...
XP_007679865  250 lmSELEGAVAESASSAGNGALDatrn------------------vspARGWMEAPLK--DANIKMALYKRILQLTGKRIP 309  Baudoinia pan...
EGS20002      274 WTPKFRASTAKKMVESWG------------------------------KEWKKAELR--DPVVKFYAAKRIQQLTGHRIP 321  Chaetomium th...
XP_013942248  241 SAEKISVEEAKEMIKSWD------------------------------PSWKNIAL---DNSLRFALRKRLYQLTGTLLP 287  Trichoderma a...
CEF76651      238 ERVEISADEAQQMVNALD------------------------------PSWKTVTLD--NDYLKFAIRKRLYQLTGHFIP 285  Fusarium gram...
EDK45407      185 DYTISKCHNLKDLYVEIeNVVNTRWK--WERNPNAIVLRKEDFT-APNIHLSEE 235  Lodderomyces elongisporus NRRL YB-4239
XP_015788627  157 SPDLHLMKTVNDVVEFY--------RtpVRGLTTYDDLARRQNElPPNLNIINQ 202  two-spotted spider mite
Q22623        150 NGKLLHLETVADVVEFY--------QtpVKNVTKYTEMARDENK-PKNVSIMEH 194  Caenorhabditis elegans
1_pfamImport   56 NGTLVHLETVADIVQFY--------QtpVKNVTKYTELARDETK-PKNVSILEQ 100 
EFO86175      149 NGKLLHLETVADVVKFY--------QepVKNITKYTEMARDETK-PKNVSIMEQ 193  Caenorhabditis remanei
XP_002631371  149 NGRLLHLETVSDIVKFY--------EepVKNVTKYTEYARDENK-PKNVSIMEQ 193  Caenorhabditis briggsae
XP_007679865  310 DPVISTSTTIADLYNHL--RTKDKPAklFQSPQIQRLKVI-----APNVAVYSN 356  Baudoinia panamericana UAMH 10762
EGS20002      322 DGKLHGYKTIEALLRHL--VDPPKAKklFEVVQQKGVFNE-----LPNVKVFPR 368  Chaetomium thermophilum var. thermophil...
XP_013942248  288 DAKLAAASTTKHILTLA--SRDPKPLklAQMLEKRNAFNE-----LTNVTVHDR 334  Trichoderma atroviride IMI 206040
CEF76651      286 DVKLAAAKTPRELIIVA-LTINKRGKklAEVLEEQKALTA-----LPNVTVHNR 333  Fusarium graminearum
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