Conserved Protein Domain Family
zf-4CXXC_R1

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pfam10497: zf-4CXXC_R1 
Zinc-finger domain of monoamine-oxidase A repressor R1
R1 is a transcription factor repressor that inhibits monoamine oxidase A gene expression. This domain is a four-CXXC zinc finger putative DNA-binding domain found at the C-terminal end of R1. The domain carries 12 cysteines of which four pairs are of the CXXC type.
Statistics
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PSSM-Id: 402223
View PSSM: pfam10497
Aligned: 53 rows
Threshold Bit Score: 122.735
Threshold Setting Gi: 307111908
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_002955702  147 IGLTCHFCRQKMLCSEEDCPRcstrnsaaqclgkstcSSCKsa---------tGIFCRACLWVRYGQVLEEVREDPDWLC 217  Volvox carter...
XP_002504705  200 ecTSCHFCRQKTADVKTSC-------------------QCArwrktppggrgrGAWCGWCLEMRMGENIDEALADAEWRC 260  Micromonas co...
XP_001420168  127 ecTTCHFCRQKTTDAKTTC-------------------VCGtwrrapeggrgrGTWCGWCLEMRVGENLDEAMADAEWRC 187  Ostreococcus ...
XP_015630077  170 LGICCHFCRQKKLCGEEGCKRcgegdlnqpcigktdcSSCHss---------yGILCRACLKVRYGEDMDEVRKNKNWMC 240  Japanese rice
XP_011666805  274 YGSTCHQCRQKTNDMKTICHS----------------ATCSgv---------rGQFCGPCLRNRYGEDAREALLDETWTC 328  purple sea ur...
EDO33918       61 NGTSCHQCRQKTDDLKTTCKS----------------ENCVgi---------rGQFCGPCLRNRYGEDAKEAIMNPQWVC 115  starlet sea a...
XP_001602151  207 NGSSCHQCRQKTKDTKTVCRS----------------GECIgv---------rGQFCGPCLRGRYGESALEALQNPHWAC 261  jewel wasp
XP_001121657  196 NGTCCHQCRQKTLDTKTVCRS----------------GECVgl---------rGQFCGPCLKGRYGENAVDALKDPNWTC 250  honey bee
XP_001944678  201 SGTTCHQCRQKTADQKSYCRY----------------KGCSgv---------rGNFCGFCLGRRYGENVASVLVNPKWAC 255  pea aphid
XP_003245746  169 KGTTCHQCRQKTLDQKSYCRH----------------QSCKgm---------rGMFCGFCLGKRYGEDVAEALLNPVWAC 223  pea aphid
XP_002955702  218 PHCYEkkhgnwrkhgwFCNSS--ICMR-KEGRLPTGIAFHKAQERGYASVAHML 268  Volvox carteri f. nagariensis
XP_002504705  261 PVCRD-----------ICNCSgaNCLRaKRGLFPTQQLTHEAIEHGWQSVAHYL 303  Micromonas commoda
XP_001420168  188 PVCRD-----------ICNCSgaNCLRaKRNLFPTQQLTGEALAYGWPSVAHYL 230  Ostreococcus lucimarinus CCE9901
XP_015630077  241 PHCIEekgt---kkfwICNSS--ICLK-KRKLSPTGIAIYDAREQGYESVAHLL 288  Japanese rice
XP_011666805  329 PPCRG-----------NCNCS--FCRK-KQGRNATGILIHLAKHNGYRSVKDFL 368  purple sea urchin
EDO33918      116 PPCRG-----------ICNCS--FCMK-KRGRRCTGILIHLAREKGFEDVKAFL 155  starlet sea anemone
XP_001602151  262 PPCRG-----------LCNCS--ICRT-RNGQRPTGILAPLAKEEGFESVKDYL 301  jewel wasp
XP_001121657  251 PPCRG-----------LCNCS--ICRT-RNGLPPTGILAPLAQEEGYSSVMDYL 290  honey bee
XP_001944678  256 PPCRG-----------YCNCS--ICRR-RKGMAPTGQLAQQAVAGGYESVRHML 295  pea aphid
XP_003245746  224 PPCRG-----------QCNCS--ICRR-HQGKDPTGQMAQEAKAKGYNSVCDML 263  pea aphid
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