Conserved Protein Domain Family
BAR_2

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pfam10455: BAR_2 
Bin/amphiphysin/Rvs domain for vesicular trafficking
This Pfam entry includes proteins that are not matched by pfam03114.
Statistics
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PSSM-Id: 402196
Aligned: 10 rows
Threshold Bit Score: 290.126
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q06523        45 R-LSIKSRT-RFVQESLGTVS-------------DISKLPPQYQFLEKKSDSLEKVCKRILLVS-KTFEVEGYDYPP--N 106 Saccharomyces c...
Q6CPI5        40 R-LSILKRR-HQLQETLGTVH-------------DISQLPIQYKFLEQKSDALEKICKRLLLVT-KTFEVEGYDYPP--N 101 Kluyveromyces l...
Q6FKU8        30 K-LSIKAKT-RFLQEAIGNER-------------DISKLPPQYVVLEKKCDSIEKVLKRILIVT-KTYEIEGYDYPP--N 91  [Candida] glabrata
Q753K3        49 TiLSLKTRK-RQLQETLGSAK-------------DISQLPPQYGFLERKCDAIEQVCKKILVVS-KTFEVEGYDYPP--N 111 Eremothecium go...
Q10253        18 SiTPFAKKTtHYLRTKIGSRV-------------EELSLPEDYVELEQQVDSLKEAYNLVLPIV-ETVEVDGYDYPT--N 81  Schizosaccharom...
XP_001528266  37 SiQPFTNKTqQLLNEQLKQVQqlasnvsalppniEVSELPKDYLELEVNCDLLLKLYTELIQSNnSTYGQLSYDYPPgnT 116
EAZ63377      37 SiQPFATKTtQLISTQLQQVQhlanln--vnsniEVSELPAEYLQLETNCDLLLKLYTDLIQYSnETFNNISYDYPPgnY 114
Q59WJ7        37 SiQPYTTKTtQLISEQLKHLEqlann---ttddiDVSELPQDYLQLESNCDLLLKLYTDLIQTTnETYGKVSYDYPPgnY 113 Candida albicans
XP_001643644  27 TiPTVAQSThRMVKEKLGQVD-------------DISPLPQEYLDLELKIDTYKSVYEHFLKIT-SIYERESYDYPK--E 90 
P40531        27 ElPSLAQSTqRMVQERLGQVT-------------DISQLPREYTELEDKVDTIKLIYNHFLGVT-AIYENGSYDYPK--Y 90  Saccharomyces c...
Q06523       107 LTESISD--WW--------------SLNKDGW--FGSKKSESSTKKKGs-----------------NHDDAFLPRSFAQA 151 Saccharomyces c...
Q6CPI5       102 LTESFND--WW--------------SGNKDSIfsFSKKKAEVSPEVKE------------------TAENGLLPRSFAQA 147 Kluyveromyces l...
Q6FKU8        92 ISESLSS--WWqtkew-----fnisELTKNVIpkHGNVEKAGTEASKTlt---------------dKEVSHEGPPSFASA 149 [Candida] glabrata
Q753K3       112 PTESISD--WWn------------tSTKETRFlkFGKGGTDKQKEDKQk-----------------QAAGSSDPPSFAHA 160 Eremothecium go...
Q10253        82 FRDSITD--FGktvsgkvrnlgnltPLEQTPLasVGKNLEEKEAAAKP-------------------------SRTLYNA 134 Schizosaccharom...
XP_001528266 117 AFNKLKDahIGdsigakfnqlknvsSPQELEKvlLGQASKDAGDDEEEgeegedrkagadgslvtiQPTSGGIPRTLFGH 196
EAZ63377     115 TITKIKDanVGgvlatkfnqlknvsSPQELENilLGKEAGDADSAEKDva---------------iQTTSVLLPKTLYGA 179
Q59WJ7       114 AINKIKDanVSgligqkfnqlknvsSPQELEKvlLGQDVDAESKDESGvv--------------siQPTSPQLPKTLFGH 179 Candida albicans
XP_001643644  91 FSESVNE--FTdsignkmyefsngvSTEGSSGk---------------------------------------tPRTLNYA 129
P40531        91 INESVNE--FSrsvaskltelthatSASEAQNilVAPGPIKE-------------------------------PKTLNYA 137 Saccharomyces c...
Q06523       152 ISKAAVDCECEFQNLehnekaelkkkkesiktaqtteaqgadhneedeedeedeeDDEDLSNLIKVFDSWSTCYKNIDEG 231 Saccharomyces c...
Q6CPI5       148 LSKAATDSALILKQLkaeetrtnqeesqegadqkp-aeetkaepeleaeadededEDEDVDNLIKAFESWTKCQLSIDQS 226 Kluyveromyces l...
Q6FKU8       150 IARAGKDSQLIFESIetk----------------------------------dedEKEDIDELVKIFKIWSDCFYEISDS 195 [Candida] glabrata
Q753K3       161 LHRAAKGSQGIIQELkeqaeee---------------------------qeqeveIDEDVESLIKMFGTWADAQYNMDIA 213 Eremothecium go...
Q10253       135 ISRAASEAT---TKM------------------------------------------GAGNPLSSAFGQISVLEEKVGNL 169 Schizosaccharom...
XP_001528266 197 LSEILAKQS---EELq--------------------------------------aKSEELNPLSFVLLQISSTYHEIAAA 235
EAZ63377     180 LSVLAEKHS---QEL----------------------------------------KTSA-APLSLALLQVSSSYLEIANA 215
Q59WJ7       180 LAEICAKHS---DEL----------------------------------------KSSE-HPLSFALLQVSSTYQEIAVA 215 Candida albicans
XP_001643644 130 VSKVSMGASEQFQKL----------------------------------------HDTDDKRIANLLTNVGNAEASIAEA 169
P40531       138 LSKVALNSSECLNKM----------------------------------------FPTEEQPLASALLQFSDVQAKIAQA 177 Saccharomyces c...
Q06523       232 KAEMDSMMVKEFNKKLETLINQDFKKVHDLRKKVEESRLKFDTMRYEVKAkeaeleakkaeatgeahskdvsakdisant 311 Saccharomyces c...
Q6CPI5       227 KAEMDSLMVKEFNAKLSKLIETDFKKGHELRAKVQDARLNFDTLRHEIKLklqekevvas---------------seeae 291 Kluyveromyces l...
Q6FKU8       196 KTEMDQMMIKEFNVKLEDYLQKNFQKIHTLRAKVEESRLNFDTMRYEVAQtskqtdskelgn------------edetkp 263 [Candida] glabrata
Q753K3       214 KREMDQFMVKEFNEKLKHLLEVEFKKGHTLRRKVEESRLTFDTLKYEQHErdaalakkq------------------dea 275 Eremothecium go...
Q10253       170 QGERDSAISKNFCEQVRAVLYPRFAEAHRVKADVQDKRLQLEMAKLDVES------------------------------ 219 Schizosaccharom...
XP_001528266 236 RLVQDDKIIKGLNNQLVEILNQQFIKVNELRKKVYLTRSQFDQLRSKHEA------------------------------ 285
EAZ63377     216 RLVQDEKILAEVNDKLVAILNEQFIKVNELRKKVYSTRSEFDLIRSKVDE------------------------------ 265
Q59WJ7       216 RLDQDKKIMSGLNAELIRTLNESFIKVNELRKKVYATRGEFDLLRSKYEK------------------------------ 265 Candida albicans
XP_001643644 170 RLLQDHSIQAKFNFQLREEIAQSIERASKYRKEVYHKRLKYDIAREKY-------------------------------- 217
P40531       178 RIQQDTLIQTKFNKNLRERLSFEIGKADKCRKDVHSMRLRYDVARTNLANn----------------------------- 228 Saccharomyces c...
Q06523       312 ttsfdETPSTEDekpksegaeeeskkeaneptvddvadrkedlksnkvndeppieesEDNKLLEKLEDEFVSNTTAAVET 391 Saccharomyces c...
Q6CPI5       292 kkvatETPETPEkktneepv-----------------------------dmakteedPDSKLFERLEDQFVSATSETVEF 342 Kluyveromyces l...
Q6FKU8       264 ssmdaNKTNTEEkeaandkvetkektetnatiad--etketkdtkdsedlkedsktsTDGQLLEQLEDEFVSNTTEAVEV 341 [Candida] glabrata
Q753K3       276 kqaegATPSTGVtqss-------------------------------------tadlAFYAQLEDAEDEFVSNTAEAVEF 318 Eremothecium go...
Q10253       220 -----AKPENLE---------------------------------------------HCKSAVRSAEDELNGAIEHAKIL 249 Schizosaccharom...
XP_001528266 286 -----TDPENEE--------------------------------------------------LIAKEDELVSATELAVIE 310
EAZ63377     266 -----TDQENEE--------------------------------------------------LISKEDELVSATEVAVVE 290
Q59WJ7       266 -----SDPENEE--------------------------------------------------LIAKEDGFVSATEVAVVE 290 Candida albicans
XP_001643644 218 -----SKHEKNG---------------------------------------------TVKVELEILEDEFNHATKDAIMV 247
P40531       229 -----KKPEKEA---------------------------------------------SLRVQMETLEDQFAQVTEDATVC 258 Saccharomyces c...
Q06523       392 MEEITDSSEILGLIKLFQNFQLVYFRQCVQEVEANLKVLNG 432 Saccharomyces cerevisiae S288C
Q6CPI5       343 LGELTDSSEIISLVKLFHNFQLIHYKQCVKSLEEDLEVLNS 383 Kluyveromyces lactis
Q6FKU8       342 MTEVSENSELLSLIKLFQTFQLSYHQHCVKSLEQSLKDLNA 382 [Candida] glabrata
Q753K3       319 MTSIADATKLISLVKLFQNFQLVYHRKCVQELEVSLNSLTS 359 Eremothecium gossypii
Q10253       250 YEQILNKDYNTDLLRSIIKNQLKFHQDAAAAL----SDITI 286 Schizosaccharomyces pombe 972h-
XP_001528266 311 MKKILKPSKNINLLKIMVQAQKEYFETSAKKLNDLLANLDK 351
EAZ63377     291 MKRLLKPSKNISLLKVFVDAQKEYFEVGAKKLAALSASLDK 331
Q59WJ7       291 MKKLLKPSKNIDLLKVLVAAQKDYFEVGAKKLKEVLDNLDK 331 Candida albicans
XP_001643644 248 MQEIISNNRFEQNLKDFAAAKLAYHEKSVDALRNLLDNAEL 288
P40531       259 LQEVISHANFSEDLKELAKAQAEYFETSAGLMKEFLSNSFA 299 Saccharomyces cerevisiae S288C
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