Conserved Protein Domain Family
Ago_hook

?
pfam10427: Ago_hook 
Argonaute hook
This region has been called the argonaute hook. It has been shown to bind to the Piwi domain pfam02171 of Argnonaute proteins.
Statistics
?
PSSM-Id: 371044
View PSSM: pfam10427
Aligned: 25 rows
Threshold Bit Score: 40.4376
Threshold Setting Gi: 170052147
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
O94687        117 SNVEFPLVTDgkEKPvkskqlrknsvtefekpietkkSKHRKSRNkflDKSsgsmeiESWDNSTSDSIIeSSSrlhesis 196  Schizosacchar...
Q9HCJ0        818 GEPSSPSTLV--------------------------------------DNGt-----AAWGKPPSSGSGwGDH------- 847  human
Q3UHC0        814 GEPSSPCTLV--------------------------------------DNGt-----AAWGKPPSSGSGwDHP------- 843  house mouse
NP_932139    1024 GEPSSPCTLV--------------------------------------DNGt-----AAWGKPPSSGSGwDHP------- 1053 house mouse
NP_932139    1024 GEPSSPCTLV--------------------------------------DNGt-----AAWGKPPSSGSGwDHP------- 1053 house mouse
Q8BKI2        972 SKSTPPAP----------------------------------------DNGt-----SAWGEPNESSPGwGEM------- 999  house mouse
Q9UPQ9        938 SKSTPPAP----------------------------------------DNGt-----SAWGEPNESSPGwGEM------- 965  human
Q3UHK8       1050 AEPSTPATTV--------------------------------------DNGt-----SAWGKPIDSGPSwGEP------- 1079 house mouse
Q8NDV7       1065 GEPSTPATTV--------------------------------------DNGt-----SAWGKPIDSGPSwGEP------- 1094 human
XP_001854407  531 GGNSGPIGPGglGGPrl-------------------gGPGNQMKS---DNM--------WGH--------GGP------- 565  southern hous...
O94687        197 lrendiRSSDSKSVGWDDNSTgfreSSKSLDHTDTSMfmeldsnsdpqfrpkyqAKSSWfAPDDPEASWGNLDDgwgetn 276  Schizosacchar...
Q9HCJ0        848 ------PAEPPVAFGRAGAPV----AASALCKPASKS-----------------MQEGW-GSGGDEMNLST--------- 890  human
Q3UHC0        844 -------AEPVVPFGRASAPA----AAPALCKPASKS-----------------MQEGW-GSGADEMNLGT--------- 885  house mouse
NP_932139    1054 -------AEPVVPFGRASAPA----AAPALCKPASKS-----------------MQEGW-GSGADEMNLGT--------- 1095 house mouse
NP_932139    1054 -------AEPVVPFGRASAPA----AAPALCKPASKS-----------------MQEGW-GSGADEMNLGT--------- 1095 house mouse
Q8BKI2       1000 ------DDAGASTTGWGNTPA----NAPNAMKPNSKS-----------------MQDGW-GES--DGPVTGARH------ 1043 house mouse
Q9UPQ9        966 ------DDTGASTTGWGNTPA----NAPNAMKPNSKS-----------------MQDGW-GES--DGPVTGARH------ 1009 human
Q3UHK8       1080 ------ITAASNASTWGSSSV----GPQSLSKSGPKS-----------------MQDGWcGDD---MPLPGSRP------ 1123 house mouse
Q8NDV7       1095 ------IAAASSTSTWGSSSV----GPQALSKSGPKS-----------------MQDGWcGDD---MPLPGNRP------ 1138 human
XP_001854407  566 ------GAI--RNGSWGDDGN----------------------------------VGNW--EEKGPGPQGGVGGg----- 596  southern hous...
O94687        277 GSWSSTDDtkhYKNEWaesinldnfNrpsqqedydkPKNTQVSRSSNHhrrydsyhpdsrsdsyrskrehydnrdtgprs 356  Schizosacchar...
Q9HCJ0        891 SQWEDEE-----GDVW---------N----------NAASQESTSS---------------------------------- 912  human
Q3UHC0        886 SQWEDED-----GDMW---------N----------NAAS--QESSSS-------------------------------- 907  house mouse
NP_932139    1096 SQWEDED-----GDMW---------N----------NAASQESSSS---------------------------------- 1117 house mouse
NP_932139    1096 SQWEDED-----GDMW---------N----------NAASQESSSS---------------------------------- 1117 house mouse
Q8BKI2       1044 PSWEEEDD----GGVW---------N----------TAGSQGSTSSHN-------------------------------- 1068 house mouse
Q9UPQ9       1010 PSWEEEED----GGVW---------N----------TTGSQGSASSHN-------------------------------- 1034 human
Q3UHK8       1124 TGWEEEEDv--EIGMW--------------------NSNS--SQELNS-------------------------------- 1147 house mouse
Q8NDV7       1139 TGWEEEEDv--EIGMW--------------------NSNS--SQELNS-------------------------------- 1162 human
XP_001854407  597 STWNEGN-----PATW--------------------NNNKKPMVGGGN-------------------------------- 619  southern hous...
O94687        357 khlekssyvyNQNFedrthlsdhgahfhlGNANDFNMqgssrkrkasdrqresrenelptkklnasdshnplaslTTDKN 436  Schizosacchar...
Q9HCJ0        913 ----------CSSW---------------GNAPKKGLqk-----------------------------------gMKTSG 932  human
Q3UHC0        908 ----------CSSW---------------GNTSKKGLqk-----------------------------------gMKTPG 927  house mouse
NP_932139    1118 ----------CSSW---------------GNTSKKGLqk-----------------------------------gMKTPG 1137 house mouse
NP_932139    1118 ----------CSSW---------------GNTSKKGLqk-----------------------------------gMKTPG 1137 house mouse
Q8BKI2       1069 ----------SASW---------------GQGGKKQMk-------------------------------------CSLKG 1086 house mouse
Q9UPQ9       1035 ----------SASW---------------GQGGKKQMk-------------------------------------CSLKG 1052 human
Q3UHK8       1148 ----------SLNWppyt--------kkmSSKGLSGKkrrr------------------------------ergmMKGGN 1179 house mouse
Q8NDV7       1163 ----------SLNWppyt--------kkmSSKGLSGKkrrr------------------------------ergmMKGGN 1194 human
XP_001854407  620 ----------V--W-------------------------------------------------------------PETSD 626  southern hous...
O94687        437 DLYINWlkSLSfFQTN 452  Schizosaccharomyces pombe 972h-
Q9HCJ0        933 KQDEAW------IMSR 942  human
Q3UHC0        928 KQDEAW------IMSR 937  house mouse
NP_932139    1138 KQDEAW------IMSR 1147 house mouse
NP_932139    1138 KQDEAW------IMSR 1147 house mouse
Q8BKI2       1087 GNNDSW-------MNP 1095 house mouse
Q9UPQ9       1053 GNNDSW-------MNP 1061 human
Q3UHK8       1180 KQEDAW-------INP 1188 house mouse
Q8NDV7       1195 KQEEAW-------INP 1203 human
XP_001854407  627 LIGGEW--GAG--VGK 638  southern house mosquito
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap