1AQ5


Conserved Protein Domain Family
Matrilin_ccoil

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pfam10393: Matrilin_ccoil (This model is not part of the current CDD release)
Trimeric coiled-coil oligomerisation domain of matrilin
This short domain is a coiled coil structure and has a single cysteine residue at the start which is likely to form a di-sulfide bridge with a corresponding cysteine in an upstream EGF (pfam00008) domain thereby spanning a VWA (pfam00092) domain. All three domains can be associated together as in the cartilage matrix protein matrilin, where this domain is likely to be responsible for oligomerisation.
Statistics
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PSSM-Id: 519348
Aligned: 18 rows
Threshold Bit Score: 45.4373
Created: 15-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1AQ5_A          5 EEDPCECKSIVKFQTKVEELINTLQQK----LEAVA--KRIEALENKI 46   chicken
XP_031802883  912 KHDQCKCENLLTFQNFANQEVRKLTER----LEEMT--RRMEVLENRL 953 
XP_030122318 1189 DNDQCKCENLVTFQNYATSEVRKLTQR----LEEMT--KRMEDLENRL 1230
NP_001315202  251 VQDPCMCEARLAFQRQTQTSIQDLNAK----LAAVT--RKIEQMENML 292 
7_pfamImport    4 VEDPCKCEAMLVFQRQTQATIQQLTAKh--iLPVVSngRQIEHLENTL 49  
XP_015212118  351 TADPCKCEAQLAFQSAVQSSIQALTTR----LDEVT--KKVQQFEYKL 392 
Q5NJJ7        257 TENACMCEAQIAFQRKVHNSIQTLSSR----LDDIS--NRVQQFDLRR 298  zebrafish
O42401        408 DEEACKCEAIAALQDSVTSRLEALSTK----LDEVS--QKLQAYQDRQ 449  chicken
XP_003971908  313 VEDPCKCEARLAFQKQTQATIQQLTAKiadvSKR------IERLESTV 354  torafugu
XP_040551837 1192 SKDQCKCENLVTFQNYATNEVRRLTQRleemtkrmedlenrlky---- 1235 chicken
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