7MKN


Conserved Protein Domain Family
RNA_pol_Rpb2_45

?
pfam10385: RNA_pol_Rpb2_45 (This model is not part of the current CDD release)
RNA polymerase beta subunit external 1 domain
RNA polymerases catalyze the DNA-dependent polymerisation of RNA. Prokaryotes contain a single RNA polymerase compared with three in eukaryotes (not including mitochondrial or chloroplast polymerases). This domain in prokaryotes spans the gap between domains 4 and 5 of the yeast protein. It is also known as the external 1 region of the polymerase and is bound in association with the external 2 region.
Statistics
?
PSSM-Id: 519344
Aligned: 546 rows
Threshold Bit Score: 34.6558
Created: 15-Feb-2025
Updated: 28-Apr-2025
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
7MKN_C         589 YR-KVtdgvV---TDEIHYLSAIEEGNYVIAQANSNLDEEGHFVEDL-VTCR--SkgEsslFSRDQVDYMDVS 654  Escherichia coli K-12
YP_003289240   510 YKgKVly------eLGPVYLTAEQEATYNVASGDVLLTRD-NFFRTKiVPVRsfN--EfitVDAINVNFLAVS 573 
WP_015198601   449 FR-PVen-aKvrnDLQAVYMTADEEDDLRVAAGDATTDENGYLIGPQ-VPVR--YrqEfstTTPDQVDFIAVS 516  Calothrix sp. PCC 6303
26_pfamImport    1 YR-EVkn-gRvlyDGAPIYMTADEEDDFRVAPGDVPIDEHGNLLGAQ-VPVR--YrqDfttTTPDQVDYVQV- 67  
A0T0D7         748 FW-RVin-gKvvkTGQPVYLTADIEDFYKIAPADIATNKDNYLTKNV-IPVR--YkqDfvnVTPSEVDFIAIS 815  Phaeodactylum trico...
Q46J22         456 FW-KVen-gRlikEGDPIYLSADLEDECRVAPGDVATNEEGKIMAEL-VPVR--YrqDfetVSPEQVDYVQLS 523  Prochlorococcus mar...
A5GVF3         455 FW-KVtd-gVvdkSGDPIYLSADLEDECRVAPGDVATDADGRITAEL-IPVR--YrlDfetVPPNQVDYVQLS 522  Synechococcus sp. R...
WP_015163739   449 YL-PVed-gLiryDLTPIYMTADEEDEFRVAPGDVPMNEEGWITADF-VPVR--YrqEfgtAEPNDLDYVAVS 516  Pseudanabaena sp. P...
WP_015169226   449 YY-PVea-gRvrrDLAPVYMTADEEDELRVAPGDIPTDESGKITSDL-VPVR--YrqEfgtASPTEVDYVAVS 516  Synechococcus sp. P...
Q2JJ19         458 YY-RVen-gVvrkDLGMVYLTADEEDEYRVAPGDVPVDAEGRITADL-VPVR--YrqEfttAHPTEVHYVQVA 525  Synechococcus sp. J...
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap