Conserved Protein Domain Family
GPI-anchored

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pfam10342: GPI-anchored 
Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family
Some members of this family appear to be serine- threonine-rich membrane-anchored proteins, anchored by glycosyl-phosphatidylinositol. In A. fumigatus these proteins play a role in fungal cell wall organisation. In Lentinula edodes this family is involved in fruiting body formation, and may have a more general role in signalling in other organisms as it interacts with MAPK. The family is also found in archaea and bacteria.
Statistics
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PSSM-Id: 370992
View PSSM: pfam10342
Aligned: 66 rows
Threshold Bit Score: 48.0646
Threshold Setting Gi: 302504008
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_002548030  26 TSPSSGDSYSGSsgsAS-VKIAWDDSDdsdsDksldnvKSYTILLCTGPDedNN-IQCLeTALVSSQTIDs----HETTV 99  Candida tropica...
Q2H7L4        21 TSPSKNDVVDPS---KG-VTVKWSTVNt--dP------SKAHLVLVNMAS--GH-TPFS-KDLG-EIDLSa----GSFKV 79  Chaetomium glob...
Q7SAW7        22 TNPKKNDVVDPS---SG-VEVKWSTVSt--dP------KSAHLVLVNMAS--GH-TPYT-KDLG-AVDLTk----GSVII 80  Neurospora crassa
EED56384      22 TSPQNGDKVDFS---Kp-YTVKWTTVPs--dP------EQVNIVLKNQTS-------SE-KEIAKNVKTSd----GKYTI 77  Aspergillus fla...
CAK96902      26 TQPQNGDQVDFS---Kp-YTIKWTTVAs--dP------SNFTIMLVNMNS---Q-PTVS-KKIA-NVKTSd----SKYTV 83  Aspergillus niger
Q5KDL8        23 ESPTKDTVWESG---TSsQTVEWEAVDt--dP------TSFEIQLVNQAG---YlTNSP-VTLVANQSTGdtgttNSATV 87  Cryptococcus ne...
O13854        23 NVPSSSDVWTSG---HI-EPLEWSVVSt--dP------LQANVWLINEVE---Y-PPTS-RYIM-TINTFd----ENATF 80  Schizosaccharom...
XP_008089989  21 TSPSINSTVTKG---SS-YELTWKAVDt--dP------SAFSIFLVNFVN---W-PPSY-TLLAENIETSa----GAVSV 79  Colletotrichum ...
Q5B872        24 TEPTANSTFAAG----StITVKWTTVDt--dP------SYFSLYLWNFVS---W-PPSY-IALALDVPSAd----ESHTV 82  Aspergillus nid...
XP_002380041  21 NKPGANSTYAAG---ST-VTVNWSTVDt--dP------TEISLYLWNFVS---W-PPSY-VPLARNVPTAd----QSYSV 79  Aspergillus fla...
XP_002548030 100 KIDNTLVPNG-YYYFQIYtVFNSGgvtIHYSPRFKL 134 Candida tropicalis MYA-3404
Q2H7L4        80 SE-KDVPSDG-GYQFNFEsTETQNtgiLAQSEQFEV 113 Chaetomium globosum CBS 148.51
Q7SAW7        81 SE-KDVPNDS-DFQFNFQsVDPLNqgiLAQSEQFEV 114 Neurospora crassa
EED56384      78 DSIWDIETGT-GYQFNFIsNSTKNtgiLAQSQIFNV 112 Aspergillus flavus NRRL3357
CAK96902      84 DKVVGIPVAN-GYQLNAEsNTTHNtgiLSQSQQFNV 118 Aspergillus niger
Q5KDL8        88 TYPDGAWPTGvAFQINLVsTDAKNsgiLAQSEQFNI 123 Cryptococcus neoformans
O13854        81 PA-LDLSPGY-GYQISFT-SIRDDsviYAQSGTFYI 113 Schizosaccharomyces pombe 972h-
XP_008089989  80 DVPCSASNSY-GYQFNAI-NGTNVyviYAQTPKFSI 113 Colletotrichum graminicola M1.001
Q5B872        83 QIPCDTNPEW-GYQLSAI-NGTNVyiiYAQGERFTV 116 Aspergillus nidulans
XP_002380041  80 QIPCDTNPEW-GYQISAI-NGTNVyiiYAQGDRFTV 113 Aspergillus flavus NRRL3357
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