Conserved Protein Domain Family
Stb3

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pfam10330: Stb3 
Putative Sin3 binding protein
This is a family of the conserved N-terminal end of a group of proteins conserved in fungi. It is likely to be a Sin3 binding protein. Sin3p does not bind DNA directly even though the yeast SIN3 gene functions as a transcriptional repressor. Sin3p is part of a large multiprotein complex. Stb3 appears to bind directly to ribosomal RNA Processing Elements (RRPE) although there are no obvious domains which would accord with this, implying that Stb3 may be a novel RNA-binding protein.
Statistics
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PSSM-Id: 402102
View PSSM: pfam10330
Aligned: 37 rows
Threshold Bit Score: 125.749
Threshold Setting Gi: 350290738
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
CAZ82006     104 ITSSLLAKyhlpeILLKHGPLAIRHLTAHLISAIPGFSSIPPAKQRRLVVGALEGRggvsgsegeagGVNGDVVFDKVGW 183 Perigord truffle
Q6CQG5       112 VTPEKLSQ-----LLLEKGPLAIRFITKALSKEIPKFADLSASKQRRLITSALETG-----------DEINSVVFAKIGW 175 Kluyveromyces l...
Q750U1       113 VTPQKLAQ-----LLLAKGPLAIRFITQALTEEIPSFKDLSASKQRRLIMGALEAG-----------DQENSVVFAKIGW 176 Eremothecium go...
CCF59616      22 ITPQRISS-----ILETNGPMAIRFITQRLSEDVPYFKDLSTSKQRRLIMHCMELG-----------DEPNSMIFEKIGW 85  Kazachstania af...
XP_003672210  81 vTPERISS-----LLIRKGPLAIRYITNELNEDIPCFKNLSSSKKRRLIMNVMEKG-----------DKKNCIIFEKIGW 144 Naumovozyma dai...
XP_001643007  31 VTPNKLSS-----LLLKRGPLAIRHITQTLSEEIPSFKDLSSSKQRRLIMSVMESG-----------DESNNVVFEKIGW 94  Vanderwaltozyma...
XP_003682509  28 VTPGKLSR-----LLLEKGPLAIRHITQALGNEIPSFKDLSSSKQRRLIMSAMEGG-----------DREGCVVFEKIGW 91  Torulaspora del...
XP_002497823  32 vTPGKLSS-----LLLEKGPLAIRHITQTLGTEIPSFKDLSSSKQRRLIMSAMEIG-----------DQEHSVVFEKIGW 95  Zygosaccharomyc...
XP_013934237 129 ITPNRIAN-----ILLSEGPLPIRHLTAHLVSQIPAFGHLSLSKQRRLIMAALEMG-----------DLQTGCVFEKIGW 192 Ogataea parapol...
EMG49931     110 ITSTRLAN-----LLIRKGPLPIRHITAQLALEVPSFDLLSLSKQRRLIMAAMEQT-----------DTVNNVVFEKIGW 173 Candida maltosa...
CAZ82006     184 GRWDARVKSDPPRSH 198 Perigord truffle
Q6CQG5       176 GQWSAAKVEDPADFV 190 Kluyveromyces lactis
Q750U1       177 GQWSARHV-KPHLFI 190 Eremothecium gossypii ATCC 10895
CCF59616      86 GQWSIKKV-NPEDFS 99  Kazachstania africana CBS 2517
XP_003672210 145 GQWSAKRIDSIDHFE 159 Naumovozyma dairenensis CBS 421
XP_001643007  95 GQWNAKIVNENENFI 109 Vanderwaltozyma polyspora DSM 70294
XP_003682509  92 GQWSAKVV-EAENFT 105 Torulaspora delbrueckii
XP_002497823  96 GQWTAKPV-AHESFI 109 Zygosaccharomyces rouxii
XP_013934237 193 GQWEARKASDEQINQ 207 Ogataea parapolymorpha DL-1
EMG49931     174 GQWAVRKIDSDYIVT 188 Candida maltosa Xu316
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