Conserved Protein Domain Family
7TM_GPCR_Sru

?
pfam10322: 7TM_GPCR_Sru 
Serpentine type 7TM GPCR chemoreceptor Sru
Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Sru is a member of the Srg superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.
Statistics
?
PSSM-Id: 370976
View PSSM: pfam10322
Aligned: 109 rows
Threshold Bit Score: 221.239
Threshold Setting Gi: 308470308
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
XP_003104390   5 IHGLPEYQNFQYTfTFSTPLAVIPLIYMTPTVAIMLKIFKSCRApSHwntAH-SMNHHIYAIIMLYFLFNTLFFISDFLR 83  Caenorhabditis ...
EGT32486       7 ITGLPQCRNFPYHfDYYTVYAIISALYAIPSFVVTGFMIKFYFKkFQk-sKKtLLRPEIFGSFLLMQVFHLIGLIFEFVT 85  Caenorhabditis ...
2_pfamImport   1 VDNLYEYTSYTYSfNFLTAFALLTGVYTIFSFYITIRMCIFYLNrRe--aVKnGLRADVFRLFLMMQVWNAFHVFLDFLI 78 
EGT35283       9 IDNLPEYYNFSYSfNVLTVFTVVTATYSIFSFWITLKMCIFYVKnRNsdvMKnGLREDVLRLFLLMQIWNAFHVLLDFFV 88  Caenorhabditis ...
Q21785         9 IDNLPEYYNFAYSfNILTIFTIVTATYTIFSFGVTLKMCIFYLKnRNsdvLKsGLRADVFRIFLLMQLWNAFHVLLDFLV 88  Caenorhabditis ...
XP_003104446   9 IDNLPEYYNFEYTfNVLSVFTIVTATYSLFCFAITIKMCIFYLKnQNsdvMKnGLRADVFRLFLLMQLWNDFHVLLDFLV 88  Caenorhabditis ...
Q20452         9 IDNKTEYSNFTYSfNVWTVFAAVTCTYTLFSFWITLKMCIFYLNnKNneeVKrGLRLDVFRLFLLMQVWKEFHVLMDFLI 88  Caenorhabditis ...
NP_505531      9 IDFQPEYFNFEYTfNFLTIFAAVTAIYGIFSFWITVKMCIFYLKhKHcneMKkVLRPDVFRIFLLMQLWKEFHVFIDFLI 88  Caenorhabditis ...
Q9XU50         1 ---mTSYADFHYEfNRYSLFAIVTGIYSMPTVYILIKLSYYFLYrKNk-cYStDLHPVLFRQFMIMQIACFFNVCIKFLI 76  Caenorhabditis ...
Q7YXA4         9 ILGEEDYIQFHYQfNIFSFLAIVNLIYGIPSIIILIKMSYFYCIhQKk-pNPnGPHPAIFRQFIVMQAMCVCHVTIRLLT 87  Caenorhabditis ...
XP_003104390  84 FSLPATGLLTAWCASIQPNHFFKLIFFCTFYFNYCTLILPFLLCLIRLVILFYPRDH----PmvsllvrsidnfrkfQIC 159 Caenorhabditis ...
EGT32486      86 FRIPNTSILTAWCAYGSHDVLIRISTYVFATCGHFKIFMAVLFCLLRVVYVFLDDEK---------------------IA 144 Caenorhabditis ...
2_pfamImport  79 VRIPLTSIFTAYCAQSKPEVLLKTLTMLFTGFAYASHILTLMFCLQRVLLIYATEYQk-------------------eTI 139
EGT35283      89 VRIPLTSIVTSYCAQSKPEILLNVLSFLFVGFVYTSHFLTLAFCVQRVSLLYSVEYQr-------------------eMI 149 Caenorhabditis ...
Q21785        89 VRIPLTSIFTSYCSLYKPEVALKILTLLFTGCVYTSHLLTLAFCVQRVALLYADEYQk-------------------dII 149 Caenorhabditis ...
XP_003104446  89 VRIPMTSIFTSYCSLSKPELSLKILSLVFTGCVYTSHLLTLAFCVQRVLLLYSIEYQkepsss---------hihffsII 159 Caenorhabditis ...
Q20452        89 VRIPLTSLFTSYCYQSKPVLLLKILSLMFTGVVYTSHSLTLAFCIQRVALLYAHEYHk-------------------dKI 149 Caenorhabditis ...
NP_505531     89 VRIPLTSIFTAYCAESKPVLILKILSLLFIGVVYTSHLMTLAFCVQRVALLYAAEYQk-------------------dTI 149 Caenorhabditis ...
Q9XU50        77 FRIPLTGVMTEWCAVTNPSGVLDFLIFINYAISYSKDFSIILFCGIRLFLMFSLRHDetriK---------------S-- 139 Caenorhabditis ...
Q7YXA4        88 FRIPLTGLMTSWCASEEPMSTLQLFVFMNTGVAYGKYISIILFCFLRVVLLFSLDHVt-------------------eKI 148 Caenorhabditis ...
XP_003104390 160 SKIMIISLPILFLIPFLCTAFMIPALGYCRRMGPPLQYGATYI--YYSGGWFGw--rNSYIHLVMSVVMCTLTIICSVLM 235 Caenorhabditis ...
EGT32486     145 KSIYYTSIPLSVLVSFSITFSILYEPVGCVQLKGPYPLGAVMMntELENRELp---lYRKIESYVIPTVMTVLIILNVMA 221 Caenorhabditis ...
2_pfamImport 140 SKVLDVLCPLLALLAHCLGIPHVLTKNSCFQMASPFPFGAVVItsSRDRHDVp---iYTIIYLICIHLMILLILATTCLM 216
EGT35283     150 SKVFNIVSPLLIIIGHCLGIPHFFNQSSCYQMGQPFPFGSIVIteN--RREMt---tYAIIYIVGTNAMIVLIVVTTILM 224 Caenorhabditis ...
Q21785       150 SKVFDIVCPILIVFGHSLGIPHLLLTTSCFQMGIPYPFGSIVItaS--RMDMp---vYAIIYAISTNAMIVLIVVTTIFM 224 Caenorhabditis ...
XP_003104446 160 SKIFNIICPLLIIIGHSLGIPHFLATSSCFQMGDPFPFGSIVItaS--RRDMp---tYAIIYVVCTNAMIILILITTILM 234 Caenorhabditis ...
Q20452       150 AKIFDIVNPLIIFVGHGFGIPFFFASSSCYQMDEPFPFGAIVItaL--RRDMvk--tYTIIYSIFSNTNITLTIILTIMM 225 Caenorhabditis ...
NP_505531    150 SKVFDIIAPSLIIIGHCFGIPHFFSTTSCYQMDKPFPFGAIVItaL--TRDMr---iYTIFYSMFSNASIILIIVTAILM 224 Caenorhabditis ...
Q9XU50       140 --LHVIIFPLLIAFAFILALPRYFSEGECTPLGAPFPHGAMIIsrGAHDDNDSethlYTIIELTMKPLTVALVILSNVFM 217 Caenorhabditis ...
Q7YXA4       149 GRLLAYLSPLFIIFAFLLALPRFFTLSTCAQLGWPFPHGAIIIrtFIDHSSSvt-psALIIGFFVQPLTVLTVFTLVVLM 227 Caenorhabditis ...
XP_003104390 236 VFKLRQSvF-NNssARTKQQSQRAETSLSITMISFIIPFINNTILTVrknfenffqlknfqiVYLTVP-SCVYYLMIFRP 313 Caenorhabditis ...
EGT32486     222 IWKIRQRnKiAT--SLNRTYNPKAERVLTVTMLLIVAPIIITELLIT---------------YEHFGV-YVVSFFNAFRP 283 Caenorhabditis ...
2_pfamImport 217 FAKLNQKrRmSS--ELNTKYNSTAEKTLTATMVLILLPIVMPAILSF---------------AAILNY-TFYSHLFLLRS 278
EGT35283     225 FAKLNQKrKiSS--ELHRKYNSKAEKTLTITMILILLPILMPAILSL---------------ADLFEY-ALYPYLFPLRL 286 Caenorhabditis ...
Q21785       225 FAKLHQKrKlSA--ELHRTYNSKSEKVLTATMIFIILPIVMPAILSI---------------VDIFAY-GLYPYIFLFRC 286 Caenorhabditis ...
XP_003104446 235 FAKLQQKrKmSS--DLHQKYNSKAEKTLTATIILILLPVVMPAVLSI---------------VDIFSY-DLYPYLFLLRC 296 Caenorhabditis ...
Q20452       226 FVKLYHKrKiTS--ELRRPVDLKSEKVLTATMILILLPVVVPSILSI---------------ANLFSS-NLYAYMFLLRC 287 Caenorhabditis ...
NP_505531    225 FFKLLQKrKiSS--ELHRKTDLKSEKVLTATMILILLPVVVPATLSF---------------VNLFAP-SAYPYIFLSRC 286 Caenorhabditis ...
Q9XU50       218 VWKLRSNkKsNN--TIMKKKKTNAERVLTATMILILLPLLVNVIIAL---------------FEYSG--SFDSIFFIIRS 278 Caenorhabditis ...
Q7YXA4       228 FKKLRDKkRiNS----TRKANKKAERVLSATMIFLLFPVIVNYSIAL---------------FEFFDLiNTISYI--VHY 286 Caenorhabditis ...
XP_003104390 314 FGNDCETVMMPWILYFTHPMFRKK 337 Caenorhabditis remanei
EGT32486     284 ILIDAKIHILTHYFYFTHPMFKVK 307 Caenorhabditis brenneri
2_pfamImport 279 LCLDARAHVVSIYFYYTHPIFKSK 302
EGT35283     287 ICLDARAHLVSCHFYFTHPIFKKA 310 Caenorhabditis brenneri
Q21785       287 ICLDARAHIVSCYFYFTHQIFKKK 310 Caenorhabditis elegans
XP_003104446 297 VCLDARAHVVSCYFYFTHPIFKRS 320 Caenorhabditis remanei
Q20452       288 IALDVRAHIVSCYFYYTHYIFKKK 311 Caenorhabditis elegans
NP_505531    287 ICLDARAHFVSCYFYFTHHIFKKK 310 Caenorhabditis elegans
Q9XU50       279 ICIDAQAHIITCYFYLSrsaakkt 302 Caenorhabditis elegans
Q7YXA4       287 ISLDAQAHVITWYFYCTHPIFKKK 310 Caenorhabditis elegans
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap