Conserved Protein Domain Family
Ilm1

?
pfam10311: Ilm1 
Increased loss of mitochondrial DNA protein 1
This is a family of proteins of approximately 200 residues that are conserved in fungi. Ilm1 is part of the peroxisome, a complex that is the sole site of beta-oxidation in Saccharomyces cerevisiae and known to be required for optimal growth in the presence of fatty acid. Ilm1 may participate in the control of the C16/C18 ratio since it interacts strongly with Mga2p, a transcription factor that controls expression of Ole1, the sole fatty acyl desaturase in S. cerevisiae responsible for conversion of the saturated fatty acids stearate (C18) and palmitate (C16) to oleate and palmitoleate, respectively.
Statistics
?
PSSM-Id: 402089
View PSSM: pfam10311
Aligned: 51 rows
Threshold Bit Score: 125.769
Threshold Setting Gi: 327304427
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
XP_003236905   4 ISSKTYIRLHALFQVVLAVYLTFARESVGGPELVYKVRDKLRIDILQPFNLPR-SPFAYCGILLLSFAIFDLTLAik--- 79  Trichophyton ru...
XP_002560159   4 ISSKTLIQAHAVFLVVIAGYLVKNPEVITDSDLVFMMGEALKIDF-PSLSSPQqSPFTFCAILIFIESLVDLVLLsnipf 82  Penicillium rub...
EPS27594       4 LSSKTLIQAHAVFTVVIAGYLLKNPAVITDSDIVFMMGEALQIDF-PAPTTPTsSPYVICSVLLFVAAAVDIVLLtslpf 82  Penicillium oxa...
EEA22762       4 LSSKTLIQAHALFTFILSVYLVISPNAITDSDIIFIIGEAMQIDLDPAMTTFQ-YPLAICAILLTGEALVDLIIVrk--- 79  Talaromyces mar...
EED15299       4 LSSKTLIQLHALFMFILAVYLITSPSSITESDLIFIIGEAMQIDLDPAMSTSQ-FPFSICAILLVSEALIDLIVVgk--- 79  Talaromyces sti...
GAD96368       4 FSSKTLIKAHAFFLFVLAVYLTKSPEVITDSDLVFILGEAMKIDVSPTFARPQ-SPFALCGILLVADALVDLIVVtk--- 79  Byssochlamys sp...
GAA90082       4 LSSKTLIQAHALFLFVLAVYLTRSPEVVTESDLVFMLGEFLNLEATPSISRPQ-SPFALCGVLLVVDALVDLILVtk--- 79  Aspergillus kaw...
EED56482       4 LSSKTLIQAHALFLFILAVYLTRSPEVITDSDVVFMLGETLQIDAAPSLSRPQ-SPFALCGILLVADALVDLILVtk--- 79  Aspergillus fla...
XP_001272585   4 LSSKTLIRAHALFLFVLAVYLTKSPEAVTESDFIFMVGEMVQIDAAPTLSRPQ-SPFAMCGILLIADALVDLIILsk--- 79  Aspergillus cla...
EEQ88659       4 LSSKGYIKLHALFQFALAIYLTRYKEVISDCDLVYNVNDVIRIDATPTFARPR-SPFAYCGVILLVFALFDLILTir--- 79  Blastomyces der...
XP_003236905  80 lpTLNHVLAVAEFIHRQqlrqqqerqqrefllqsrassssssstalpppvisrsrlpytrppasrssstsstastdsdss 159 Trichophyton ru...
XP_002560159  83 heALDEALPYIRPLRNGnlpaedlqvlqslpey----------------------------------------------- 115 Penicillium rub...
EPS27594      83 hdALNDALPYIRPLRNSnlpaedlqalarlpey----------------------------------------------- 115 Penicillium oxa...
EEA22762      80 lpQIDDILSTVQHEQRRtedtgfsritlqkpkqni--------------------------------------------- 114 Talaromyces mar...
EED15299      80 lpQLDSILTNLQREQRQtedrgfsritlqkpkqti--------------------------------------------- 114 Talaromyces sti...
GAD96368      80 vpQINEVLARADVARSRsngstavisnnpfa------------------------------------------------- 110 Byssochlamys sp...
GAA90082      80 ipQINEILAMAQAARVQspipvagavrtnpfm------------------------------------------------ 111 Aspergillus kaw...
EED56482      80 vpRINEIIAMAEIARSAaptsiagamrtnpfl------------------------------------------------ 111 Aspergillus fla...
XP_001272585  80 vpWINEIIAMAQAARSEsavpvpgamrhnpfl------------------------------------------------ 111 Aspergillus cla...
EEQ88659      80 lpLINQLISITRRLFDSrlanssgrsrtsrtsrtspsspss--------------------------------------- 120 Blastomyces der...
XP_003236905 160 tstelneaalkitaefsslyrqlcillITLRSWIFMIVSLQIYLSSDMEWGAastalpstatvagmpatstlaantmatp 239 Trichophyton ru...
XP_002560159 116 ------------itksltiywsvwiavAACRFAVYAAIAFFIYQ------------------------------------ 147 Penicillium rub...
EPS27594     116 ------------itksltmywniwvavSAVRFALYGALSFYIYQ------------------------------------ 147 Penicillium oxa...
EEA22762     115 ---------naltiqlatlyneiwtfiACVRFCFFFAVSLFIYTSGGNA------------------------------- 154 Talaromyces mar...
EED15299     115 ---------nswtiqlatiyneiwtfiAGARFVFFFAVSLFIYTGDS--------------------------------- 152 Talaromyces sti...
GAD96368     111 -------------irmaalyseiwtllAASRFCLFFAVSIFIYQSKPVAWGVg--------------------------- 150 Byssochlamys sp...
GAA90082     112 -------------arltslyseiwtllSAARFCIFFAVSFFIYQSQPSAWGM---------------------------- 150 Aspergillus kaw...
EED56482     112 -------------arlaslytdiwtllSASRFCLFFAVSFFIYQSKPSDWGV---------------------------- 150 Aspergillus fla...
XP_001272585 112 -------------arlaslyseiwtllSAVRFCLFFAVSFFIYQSKPDAWGV---------------------------- 150 Aspergillus cla...
EEQ88659     121 ---palstakkmlriynsifthmcillAVTRCLVFSIISIRIYASATDIWVPaa-------------------------- 171 Blastomyces der...
XP_003236905 240 fqsaagktilwldqnmhftRDGPSTAAAlsgsalGYDVIDLKRKIVLGYGVLELMFSCWILFALRHEKKQA 310 Trichophyton rubrum CBS ...
XP_002560159 148 -------------------GKGDHLASSytsaaaIGGLDRLKNRVVFSFAFFEMMFWFWTFSTLREERQER 199 Penicillium rubens Wisco...
EPS27594     148 -------------------ARGSYMVASyaaktaPTGLAQLKSRVVFTFAFMEMMVWFWVFFTCREERQQR 199 Penicillium oxalicum 114-2
EEA22762     155 -------------------GKASLEWSDddagqiKLGLEQVKSRVVFTYAFVEMMFWLWTLSNVREERREV 206 Talaromyces marneffei AT...
EED15299     153 -------------------SGATGKKSWvgqgqvRNGLDQVRNRIVFTFAFVEMMFWLWALSNVREERREV 204 Talaromyces stipitatus A...
GAD96368     151 ------------------aSEA------------MSGLDQLKNRVVFTYGFMEMMFWLWILLTLREERQET 191 Byssochlamys spectabilis...
GAA90082     151 -------------------DAATGMGNYgtagaaTSGLDQLKNRVVFTYGFMEMMFWLWIFITLREERQEA 202 Aspergillus kawachii IFO...
EED56482     151 -------------------DVRHTVDGYgqe--saSGLNQLKNRVVFTYGFMEMMFWLWIFLTLREERHEI 200 Aspergillus flavus NRRL3357
XP_001272585 151 -------------------NVTARGTEYsst-eaLSGLDQLKNRVVFTYGFMEMMFWLWIFITLREERQEI 201 Aspergillus clavatus NRRL 1
EEQ88659     172 ------------------aAS-----GMqdtaalDAKAIHMKNKVVLGYAVIEMMISSSTLLSLKDERRQv 219 Blastomyces dermatitidis...
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap