Conserved Protein Domain Family
Tmpp129

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pfam10272: Tmpp129 
Putative transmembrane protein precursor
This is a family of proteins conserved from worms to humans. The proteins are purported to be transmembrane protein-precursors but the function is unknown.
Statistics
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PSSM-Id: 402062
View PSSM: pfam10272
Aligned: 36 rows
Threshold Bit Score: 363.509
Threshold Setting Gi: 341903460
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
CCD80066      36 FCIMAPTTEFISA-GVTLENLFNRFLGNESQYFVQYHLKRTVMVRLFSSSLVF---LYF---MFMQFLSKnvavsa--pn 106 Schistosoma man...
ETN63031      16 FFIIFPTTEIESF-GLTVDNLCSRYLTGDN--FVQYHMKLTTVKMLIHFTMPAtyvGYM---RLLRWLNPddfkph---l 86  Anopheles darlingi
EFX71879      13 FCFIFPPSAFVSA-GITVSNLFDSWLGSEDLQFVQYHLSRTLVTVIIHSLLPL---GFF---GGVLLVEGyaqll----- 80  common water flea
KJE90682      16 gCLVFPPPALVSE-QLTLDALLASFGPREDRSYIHHHMHMTTLTLAAHALLLL---GFVagtAGLLHDDPswna------ 85  Capsaspora owcz...
EGT59395      46 cVMAYPPEGVLDElGVTLFDFFSVIYVRQRYNFIEYSSKRIIFFKTFLAMWPSaisFYFvhgylrwksvh----gsrfpe 121 Caenorhabditis ...
1_pfamImport   1 FALVFPPEELLDGlGITLFDLFSILKDPEQYGFIEYVCKRQTFFKTFVALYPAafsGYFvhgnmfmrkef---gisrfpe 77 
XP_002644008  46 FALAFPPEELLDGlGLTLYDLFSIIYDQRNYSYIDYAAKRVLFFHVFVASYPAlisGYFvhgqlfttain----trrfpe 121 Caenorhabditis ...
EFO89927      46 FALVFPPEELLDGlGLTLFDLFTIIYNSRHYGFVEYAAKRVAFFHAFVAAYPCvisLYFvhgnlfmtavd----trrfpe 121 Caenorhabditis ...
CDS41676      27 FALVAPPNVLLSA-GLTIENLFHRLLGSEELFFTAYHLRRTAILKALSFFIPL---GYF---ITLRTFGNpem------- 92  Echinococcus mu...
XP_320697     16 FFTIFPTAEMESV-GLTVDHLCSRYLSADT-DYVMYQLKSTSVKLLIHSAMPF---IYVlfiWLMMWANPdemmvvqrqp 90  Anopheles gambi...
CCD80066     107 isfpFTIWDVILWIGIgGLSIIGSHTYlVWYGSGTWYGHPTILSLKQTImESlpdSQSSSSttassslsngafgvalkaL 186 Schistosoma man...
ETN63031      87 spmvAHFNHHGLLLAAvLLLAALAVAVaVYWAWNGWSNHPTAKHLQQFInETt--MRDWRA------------------V 146 Anopheles darlingi
EFX71879      81 llvqTPLGLGFLSLSV-LLPAAAAFKV-FFWWTNNWSSHPLVNSLTSYAnNG----RQWND------------------V 136 common water flea
KJE90682      86 tpelLQYAAMLLAVAAvVLAFTMLAHA-FRWSLLDGEYHPSARNLSAYS-------PTWRH------------------L 139 Capsaspora owcz...
EGT59395     122 lldfPLIWYGAFVVSV-------IGAIaYYMRIKDYEQWPIYQYFVENPe-----------------------------V 165 Caenorhabditis ...
1_pfamImport  78 lldnPIFWNTFFVISI-------FSALvYNYHISDYKKWPFYQYFIDNPe-----------------------------C 121
XP_002644008 122 lfdhPWLWLLVFVTSV-------IGLVtYYYKIREYTQWSAFQYFMDHPe-----------------------------T 165 Caenorhabditis ...
EFO89927     122 pldhPYMWFTAFVISV-------IGAAlYCNRIKDYKQWPVYRYYNEHPd-----------------------------A 165 Caenorhabditis ...
CDS41676      93 -gflNAVGNVGLALSIaQVAIASFYIYlEWYAHGKWTGHPGMQEMRKIAeSIsssSFS-TSptssneleflrshpspegV 170 Echinococcus mu...
XP_320697     91 splgETVWDVFCSAAG-TLLIVAAVTV-FYWAQDGWSNHPIAKQLQLLTsAT---LPDWRS------------------V 147 Anopheles gambi...
CCD80066     187 ISSINSEYQRSDKFVAGQGsls-tnwSgRRFVITDSWILTSRFTEFKIVKQSSENMLAVVV------------------- 246 Schistosoma man...
ETN63031     147 ATNINDECRRVTKMVVRLN-------TlSKLVVTENWIVEIRQYGINVAHQNAAVMIVCEV------------------- 200 Anopheles darlingi
EFX71879     137 ASEINAEFRRIDKVTVRTN-------PvSKTVVTNSWIIKVEPYVVQVAHQNHVSLQLENA------------------- 190 common water flea
KJE90682     140 ARQIDMECRRMDCVVVNSH-------E-AQLVITSDWILQRTWYNLHIANHNDVDMSILGS------------------- 192 Capsaspora owcz...
EGT59395     166 ANDVELVLGNAEAFRVSCS-------QrTLVVVTAEYFIYSSNWRYVAVKNADVRFVADHA------------------- 219 Caenorhabditis ...
1_pfamImport 122 LNQVEELVSEPDTFKIRFC-------AhTFLYCNRNFFAYVSNWRLVAVKQADLRLLVDNT------------------- 175
XP_002644008 166 LDGVETVINDPETFRIRLS-------QrTHVYVTRNFFIYSSNWRFVAVRIIDVRLQVDNT------------------- 219 Caenorhabditis ...
EFO89927     166 LEEAQDVISSPDTFRVKLS-------QrTFLFVTRSFFVYSSNWRFVAVKIADLRLQVDNT------------------- 219 Caenorhabditis ...
CDS41676     171 ASSIDKEFRRMEKFVAFAGrgltsswSgRRIVVTPSWILFSHRTTFLPICQLLGHLGAVVV------------------- 231 Echinococcus mu...
XP_320697    148 ATNINDEYRRDTKIIIRSN-------AiSTLVVTESWIIKTNMYVHNIIPQSEALLYAYKVsgrmlfllsrprsliplpv 220 Anopheles gambi...
CCD80066     247 -------SAFSVL---DPSSltqdgqp--------dgeslgVQTIVTVRF---------IRTDTGVCLLSFGFPASNLDE 299 Schistosoma man...
ETN63031     201 -------NTQDVIt--DTIE---------------------ESQFVNITVhqlhqqrqqQQRQQGTTSFKLRLNGVHYND 250 Anopheles darlingi
EFX71879     191 -------EEHTYT---ADSQ---------------------TAQYLWVNV---------EHIQTKQKLFTIRLNAVDYAD 230 common water flea
KJE90682     193 -------ETIPIAarpAAEAmhanpqlaalayttggvasdhTVQMIRIHV---------TAATPGVQPFDIRLNSTDFSA 256 Capsaspora owcz...
EGT59395     220 -------RPPAVLimdDGEE---------------------RLRSIYIRG---------NFTPNYIPSLPLALRLDHFRA 262 Caenorhabditis ...
1_pfamImport 176 -------RMPMIPn-mDDEE---------------------RLRHIFVIV---------SFRQPYLPVFTISLRHDLYRQ 217
XP_002644008 220 -------RMPMIMnihDEEE---------------------RLRAMFIKV---------NFNVPYLAPFTMTLRQDYYHQ 262 Caenorhabditis ...
EFO89927     220 -------RMPLLPnnqDEEE---------------------RIRYIFVKV---------RFRPEYLQSFTITLRQDYYRM 262 Caenorhabditis ...
CDS41676     232 -------GTRCITnqiASLGedeeqer-------adpmlgsGVVMATIRI---------ADMDSGACILSFDLPASELEN 288 Echinococcus mu...
XP_320697    221 sphtpqiDTKEVIt--DTLE---------------------SAEFVNIGVk--------PQQQSRIKPFIIRINVVHIKD 269 Anopheles gambi...
CCD80066     300 LRSKLRFPLIQAQGVQLEPTIIQRFIEAFTQVVDENQPVNLP---SGyELGQ-CIGCMV--QQVNVTLNRQCessltsss 373 Schistosoma man...
ETN63031     251 LRDRVRCPVHVLPSVKF-QSLNDRFVEAFREVIARNGTVVPAa--GPiAGDS-CLACLQ--AQPDVKIEKRCldv----- 319 Anopheles darlingi
EFX71879     231 MQDRLQTRISNVRGLLINQDVHARFSKVFIEEVSLNPVFQ-----SQeEMDP-CLGCAV--NSANIRLIRRC-------- 294 common water flea
KJE90682     257 IQDKLTTIIRNAQSIVIAQTLSDRFVTAFLETVSQNPVYPHPassSHvATDDmCVGCMA--HPPRAKIVQRC-------- 326 Capsaspora owcz...
EGT59395     263 INETLPVPIFIPAGLKIPLTVMDEMLQDFALRITKNSRVTYQq--KRsDKRA-CFGCANnyEDKMVVLRKTCtgtep--- 336 Caenorhabditis ...
1_pfamImport 218 LNEVLAVPIIVPAHITIPLTIMEELKEDFIERVAQNDRHIHHa--KAsDKEP-CFACGT--EENIIKIVKTCadnne--- 289
XP_002644008 263 LNEILEIPIFVPPHITVPMTIMEELKEDFVHRIRNNSRHTHRv--KRsEQDP-CFACGS--EENIIKISKSCtgeeq--- 334 Caenorhabditis ...
EFO89927     263 LNEVLEVPIFVPPHINVPMTIMEELKEDFIDRIETNSRYLHRv--KRsDLDP-CFACGT--EENIVKIEKTCtgqep--- 334 Caenorhabditis ...
CDS41676     289 FRLYLCCPLVYAQGVSLEPSIIQRFLEAFSAVVQENEPIEIP---PSmELER-CIGCLS--NQTSVAIRRSC-------- 354 Echinococcus mu...
XP_320697    270 LRDRLQQPILVMPSVQF-RTLTERFVEAFKEEVAQNPTVPSAy--VPdEGDC-CLACLH--AQPDVKIAKYCldv----- 338 Anopheles gambi...
CCD80066     374 sslanNSNQSLNNNQCGICYCRPLWCLECLARWFASRQTNMHrpTTQWLSGRVPCPTCRTYFCARDVS 441 Schistosoma mansoni
ETN63031     320 ---dqAGNLLPDADRCEPCHCRPHWCLSCLAVWFASRQERSE--WNTWLSRKATCPMCRARFCVLDVC 382 Anopheles darlingi
EFX71879     295 -------LPTGNADGCTPCFCRPMWCIHCLSKWFSARQDAEH--PESWLMSRCPCPTCRSPFCVLDVS 353 common water flea
KJE90682     327 ----------QTPTACTPCYCRPMWCLECLGKWFASKQNPAA--TSNWLNGTAQCPTCRATFCLLDVR 382 Capsaspora owczarzaki ATCC ...
EGT59395     337 rtgfhELGLR-LQPPCDGCLCEPLWCVSCAGRIFVMKQTSDNvhRDEYHLGSCPCPFCRKSFCIHDVH 403 Caenorhabditis brenneri
1_pfamImport 290 rwqwsREGQRVYTDQCQVCVCRPLWCNRCIAQIFIGKQNIDAvyRHDYWRGTAQCPTCRKAFCIRDVH 357
XP_002644008 335 rllfhDVVLN-PTPNCENCTCRPLWCCGCIAQIFITRQKIDNvnRYEYHRGSGKCPTCRKTFCIRDVH 401 Caenorhabditis briggsae
EFO89927     335 rvlfhDTGLR-FTPPCENCTCRPLWCRNCIAQIFITKQNVDNiyRYEYFRGSAQCPTCRKNFCIRDVH 401 Caenorhabditis remanei
CDS41676     355 ------------AGECGSCRCRPMWCEMCVGRWFASRLAQSHvpTSEWVASRVPCPTCRSPFCIRDVL 410 Echinococcus multilocularis
XP_320697    339 ---daAGSVLPEQERCQPCGCRPLWCVSCLATWFASQQQRAE--RDTWLSKKTTCPMCRARFCVRDVC 401 Anopheles gambiae str. PEST
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