6WB9


Conserved Protein Domain Family
MMgT
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pfam10270: MMgT (This model is not part of the current CDD release)
Membrane magnesium transporter
This entry represents a novel family of membrane magnesium transporters (MMgT). The proteins, MMgT1 and MMgT2, are localised to the Golgi complex and post-Golgi vesicles, including the early endosomes, suggesting that they may provide regulated pathways for Mg(2+) transport in the Golgi and post-Golgi organelles of epithelium-derived cells.
Links
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Statistics
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PSSM-Id: 519287
Aligned: 66 rows
Threshold Bit Score: 66.9014
Created: 15-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
6WB9_5         9 YTVSALVLFHSGFSSYEFHHLLKl---nSLnnAQGAISKLPK-----DIMYETYAGLILFVLAVFTsfeklqylpiesnd 80  Saccharomyces c...
XP_006688209   1 -mLGIALLLHCAYSAYEYN-------------------KLPIsynrsDLLLELVISLCLIFYSSVTniqmpsrln--ldn 58 
XP_003684730   9 IVVSLLQLFHAGFSSSEFQQLLKt----QQlhKYLNEAGLPL-----DIKLEVFMGLIIFVIGIFLsfeklqfqp-ielt 78 
XP_004180481   9 fGVGIIQLLHAGFSSYEFHQLLKsstniNEssNEQKLYQLPN-----DIKLEVFISLAILTVSIFLsfnklkyypinnkn 83 
Q6FQL2         9 YAVSLLQLLHAGFSSYEFHQVMk--------kHNRVGAQLPQ-----DIKFEVLCAIIIFTLGVFLsfevlqyyp-lrge 74  [Candida] glabrata
Q6CIC4         9 YFIAWIQIIHSGVSSYEFHQIVKh---iILenPDAKTPGLPD-----DVKLEALCGLLFFILGTFIsqsklkyls-irge 79  Kluyveromyces l...
Q75B02         9 LAISVLQLVHSGFSSFEFHRLKRh---lTLadGIPQGFRLPS-----DIKAEVVCALVLFTLGIFLsfeklqhlp-ltgs 79  Eremothecium go...
XP_003646231  10 STLSILQLVHSGFSSFEFYQLKKq---lSLidGLQQDITLPY-----DIQLEVLCGLLLFTLSVFLsfeklkyip-lvrs 80 
XP_003674264   9 fLIGSIQLLHAGFSSYEFYQILKn----VT---TEKKLTLPK-----DIQYETILGLLFTVFSIFLsfdkksyypihmlk 76 
XP_022465942   9 YFVSVLLLLHAAFSSFEYHQLMKn----AAq-DTARTPPVPR-----DIVYETYAALALFITATILshnkltyyn--lft 76 

6WB9_5        81 gkiisQGNYLKEIALNKATNVDNLIGSNPNGEIIFTPSFVDVHMKRKIC 129 Saccharomyces cerevisiae W303
XP_006688209  59 eivhsPSPYLNFIHINKSLKESNEFGIDDYSKFSNRLDFIDIVKMRREY 107
XP_003684730  79 rptviTGEYLSDIRYRKATNVENLTGSNLEGQIIYTSNLTDVHQKRKEC 127
XP_004180481  84 deiitEGEYLSNIQMSKASNVDNLVGSDPTGYITYLPNMVDIQAKRKEV 132
Q6FQL2        75 ekplgPKQYLLDIKLNKSSNIDNLVGVDPNGEVSYTPSFVDIKEKREQV 123 [Candida] glabrata
Q6CIC4        80 eriieTDEYLKPIELNKASSTDVVINNDPYGEINYLPSFVDIHAKRKLF 128 Kluyveromyces lactis
Q75B02        80 rtpltQDLYLHEIRMSEATKTDNLIGSETYGDFTFMPSFIDVHARRKEI 128 Eremothecium gossypii
XP_003646231  81 relltQNQYLQEIQMNKATKKDNLIGNDPFGEFSCMPSFINIHRKRKEI 129
XP_003674264  77 rddiiKGEYLQDISLSKATDVDNLIGSNPTGEVSYTPNFIDIHEKRKSV 125
XP_022465942  77 lkrvsQDEYLRDTALRRATTVDNMIGNDPAAEVTHTPNLADIMSKRKEV 125
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