Conserved Protein Domain Family
MMgT

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pfam10270: MMgT 
Membrane magnesium transporter
This entry represents a novel family of membrane magnesium transporters (MMgT). The proteins, MMgT1 and MMgT2, are localized to the Golgi complex and post-Golgi vesicles, including the early endosomes, suggesting that they may provide regulated pathways for Mg(2+) transport in the Golgi and post-Golgi organelles of epithelium-derived cells.
Statistics
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PSSM-Id: 402060
View PSSM: pfam10270
Aligned: 68 rows
Threshold Bit Score: 68.0592
Threshold Setting Gi: 187037062
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_009217326     9 TTFGLVLLAHACYSAHEHSVLQQstaspsaaassspsgtGAaaVAAAATataassSLPV-----DISIETVVALVVMCLG 83  Gaeumannomyce...
EGV62039         1 -mLGIALLLHCAYSAYEYN------------------------------------KLPIsynrsDLLLELVISLCLIFYS 43  Yamadazyma te...
XP_002492769     9 YVIGSLLLLNAGYASYTFNQVAk-------------------rVLDHNL------ELPL-----DIKIEALVACVIVALG 58  Komagataella ...
Q75B02           9 LAISVLQLVHSGFSSFEFHRLKRh--------------lTLadGIPQGF------RLPS-----DIKAEVVCALVLFTLG 63  Eremothecium ...
ybcl:Ecym_4354  10 STLSILQLVHSGFSSFEFYQLKKq--------------lSLidGLQQDI------TLPY-----DIQLEVLCGLLLFTLS 64  Eremothecium ...
Q6FQL2           9 YAVSLLQLLHAGFSSYEFHQVMk-------------------kHNRVGA------QLPQ-----DIKFEVLCAIIIFTLG 58  [Candida] gla...
CCK71697         9 YFVSVLLLLHAAFSSFEYHQLMKn---------------AAq-DTARTP------PVPR-----DIVYETYAALALFITA 61  Kazachstania ...
CCH60962         9 fGVGIIQLLHAGFSSYEFHQLLKsst-----------niNEssNEQKLY------QLPN-----DIKLEVFISLAILTVS 66  Tetrapisispor...
XP_003684730     9 IVVSLLQLFHAGFSSSEFQQLLKt---------------QQlhKYLNEA------GLPL-----DIKLEVFMGLIIFVIG 62  Tetrapisispor...
Q6CIC4           9 YFIAWIQIIHSGVSSYEFHQIVKh--------------iILenPDAKTP------GLPD-----DVKLEALCGLLFFILG 63  Kluyveromyces...
XP_009217326    84 LAL-------------------GTPLLRPIQWREWAGKIEREGAegffpaggdseevarefigNPFRYLESRPAFVDIRK 144 Gaeumannomyce...
EGV62039        44 SVTniqmpsrln--ldneivhsPSPYLNFIHINKSLKESNEFGI-------------------DDYSKFSNRLDFIDIVK 102 Yamadazyma te...
XP_002492769    59 AILsieasdqvdiysgalvkprDQSGLKNIFMGEATGEHEIIGT-------------------TPFDHIESNVEFINIIK 119 Komagataella ...
Q75B02          64 IFLsfeklqhlp-ltgsrtpltQDLYLHEIRMSEATKTDNLIGS-------------------ETYGDFTFMPSFIDVHA 123 Eremothecium ...
ybcl:Ecym_4354  65 VFLsfeklkyip-lvrsrelltQNQYLQEIQMNKATKKDNLIGN-------------------DPFGEFSCMPSFINIHR 124 Eremothecium ...
Q6FQL2          59 VFLsfevlqyyp-lrgeekplgPKQYLLDIKLNKSSNIDNLVGV-------------------DPNGEVSYTPSFVDIKE 118 [Candida] gla...
CCK71697        62 TILshnkltyyn--lftlkrvsQDEYLRDTALRRATTVDNMIGN-------------------DPAAEVTHTPNLADIMS 120 Kazachstania ...
CCH60962        67 IFLsfnklkyypinnkndeiitEGEYLSNIQMSKASNVDNLVGS-------------------DPTGYITYLPNMVDIQA 127 Tetrapisispor...
XP_003684730    63 IFLsfeklqfqp-ieltrptviTGEYLSDIRYRKATNVENLTGS-------------------NLEGQIIYTSNLTDVHQ 122 Tetrapisispor...
Q6CIC4          64 TFIsqsklkyls-irgeeriieTDEYLKPIELNKASSTDVVINN-------------------DPYGEINYLPSFVDIHA 123 Kluyveromyces...
XP_009217326   145 QRKEF 149 Gaeumannomyces tritici R3-111a-1
EGV62039       103 MRREY 107 Yamadazyma tenuis ATCC 10573
XP_002492769   120 RREEF 124 Komagataella phaffii GS115
Q75B02         124 RRKEI 128 Eremothecium gossypii
ybcl:Ecym_4354 125 KRKEI 129 Eremothecium cymbalariae DBVPG#7215
Q6FQL2         119 KREQV 123 [Candida] glabrata
CCK71697       121 KRKEV 125 Kazachstania naganishii CBS 8797
CCH60962       128 KRKEV 132 Tetrapisispora blattae CBS 6284
XP_003684730   123 KRKEC 127 Tetrapisispora phaffii CBS 4417
Q6CIC4         124 KRKLF 128 Kluyveromyces lactis
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