Conserved Protein Domain Family
Stork_head
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pfam10264: Stork_head (This model is not part of the current CDD release)
Winged helix Storkhead-box1 domain
This is the conserved N-terminal winged helix domain of Storkhead-box1 protein which is likely to be a DNA binding domain. In humans the full-length protein controls polyploidization of extravillus trophoblast and is implicated in pre-eclampsia.
Links
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Statistics
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PSSM-Id: 491043
Aligned: 14 rows
Threshold Bit Score: 122.805
Created: 21-Aug-2024
Updated: 4-Dec-2024
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
XP_015793117  237 MSLVCQAKFTPLTEALCKCINDFNNRSTHVFLGDIAEAIKQSYPNIIPPTADMIKKTLRSLQRAGKVrFSTSEGYFLVKP 316 
XP_011153522  140 VAPVSQGQFTPLPEALCWAILELTSQRQAATLDTLRSALRNAFPAMQRPSRELVYDALAKLMQERKI-YHTSQGYFVVTP 218 
EFX83794       72 VQPISQSQFTPLPEALCWVIWELNLAERSTALDDVTAALGNAFPDLVPPSNKVVYDTLGKLIRDRKI-FYNGKGYGVVTP 150 
XP_002410700   32 MVQVLQTQFAPLAEALCKAVFDLTSRGDTATLDTISAQLTAAFPAIERPGSDVVYRALGALIRERRL-YHTGVGYQRIIG 110 
NP_001116482  113 MSPISQSQFIPLSEILCSVISDLNADHVVVNQEALINYMMKSHPGMTIPTQDILYNALGTLIKERKI-YHTGEGYFVVTP 191 
XP_003258247  111 MNPITQSQFVPLGEVLCCAISDMNTAQIVVTQESLLEHLMKHYPGIAIPSEDILYTTLGTLIKERKI-YHTGEGYFIVTP 189 
2_pfamImport    1 MSPIAQCRFVPLAEVLCCAIADMNAAQVMVTQQSLLEHLIKHYPGIAVPSPDILYSTLGALIQERKI-YHTGEGYFIVTP 79  
EDX11326      118 VTPTVQGQFTPLPEALCDVIMDLTAEGQSATIEHVRSKLGSRFPHMTTPATEVIYDSLAQLMQEQKI-YQTSKGYFIFTP 196 
Q7Q578        118 VTPIVQTQFTPLTEALCDVIMELTSQGQSATIENIRNRLRSRFTHMQQPSVEVIYDTLVQLMQEIKI-YQTSKGYFIVTP 196  Anopheles gam...
XP_002432938   21 VSLINQGQFTPLPEALCWVILELTSSGQHAVLESIRNCLHLSFPDIEKPSSQVVYDTLAKLMSDKKI-YQTSQGYFIITP 99
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