Conserved Protein Domain Family
LIDHydrolase

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pfam10230: LIDHydrolase 
Lipid-droplet associated hydrolase
This family of proteins is conserved from plants to humans. The function is as a lipid-droplet hydrolase in the yeast members.
Statistics
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PSSM-Id: 370901
View PSSM: pfam10230
Aligned: 24 rows
Threshold Bit Score: 238.731
Threshold Setting Gi: 74689293
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q0UFS1        25 TTYLIYFITGNPGLIEYYRTFLTHLYGVlsqnta-----sdrsiEFQVYGRSLSGFEVNSSEiktykyrRDPPYGLQDQI 99  Parastagonospor...
Q00TT1        75 RGPRVFVVPGNPGVARFYETFASSLSERld--------------aRAVDVVGYLGHTERDRPg------RREWFTLDEQK 134 Ostreococcus tauri
Q0WPD9        37 PTFHVLFIPGNPGVVSFYKDFLESLYEFlg-------------gNASVIAIGQISHTSKDWE-------SGRLFSFQEQI 96  thale cress
Q0CD92        29 SPIVIYLIAGNPGLIGYYHTFLSLLSENiksqai----rqeqkcTYHVYGHSLAGFELEERAsdd-avpHARYYDLEEQI 103 Aspergillus ter...
XP_001274264  31 PPITIFLISGNPGLISYYHTFLSLLSEKlnqklkshttsqvhppSFQIYGHSLGGFALQTPQh-----pHPCDYDLEDQI 105 Aspergillus cla...
Q0UDR2        26 GEYVIYMLPGNPCIMTYYQPFLSTLFTSinaal------sprhmSAHVGGYTPPGFRVSPGHis----eVKLPASLQDQI 95  Parastagonospor...
Q6C1F7        10 EPILTVVVPGNPGIDLFYRTFLALLAQKs--------------pRFDLVCDSLRGFEEEEALaea--aeSESGFGLQDQI 73  Yarrowia lipoly...
Q6BXR7        26 VRPLLVLIPGNPGLVDFYITYLNLIQKRn--------------pNLEILCISHAGFKSDGNIidd--dsVFTYYNLEFQI 89  Debaryomyces ha...
Q753K6        38 PECILIFLPGNPGLINFYREFLRSIHEKn--------------pTWEIVGISHTGMSAKTGPe-----dLKRVYTLVEQV 98  Eremothecium go...
Q6FKU7        28 SSPLFVWIPGNPGLLEYYQEFLAKVHDKn--------------pTWEILGISHAGTVIESSQlkkfrknPLPIYDLKQQT 93  [Candida] glabrata
Q0UFS1       100 RHAEDDVVELVEdl-----kDNGAKDVRVILVGHSVGAYISLEIVR--RLRAhgvage--------dfdtrISGVVGLFP 164 Parastagonospor...
Q00TT1       135 AHVRDYVDATLR--------ASSDDRRECVVVGHSIGAHLALFTAK--ELGFd-----------------rIDGVVGLMP 187 Ostreococcus tauri
Q0WPD9        97 DHKIDFIRQELEs-----------vKVPIILVGHSIGSYISLELLK--KFSDk------------------VVYCIGLYP 145 thale cress
Q0CD92       104 RFVQNKLDTFIAtlkgisagASSNPKPKVILIGHSVGSYIAMETLR--RHRDrtksgd-------spidfdIIGGAMLFP 174 Aspergillus ter...
XP_001274264 106 GYVQGKLDEFLSspeg-cgsSAAEGKSKVILIGHSVGSYIAMEILR--RHREraasaaaataphgstasfdIIGGIMLFP 182 Aspergillus cla...
Q0UDR2        96 GYAKKLIDAAIKq------hIKSASRPKLILVAHSIGTYMALEILR--RYKDghstl----------ahadIIGAVLLCP 157 Parastagonospor...
Q6C1F7        74 NHFVALVRSRFDp----------kKHVGLIIMGHSVGAWIVQRVAC--QVSTedp-------------kipISLVGLLTP 128 Yarrowia lipoly...
Q6BXR7        90 EHKIDILKYFI---------LNENRNTELYFLSHSVGSYINQRVVH--RLLNnselq----------nkmdIKFLGLICP 148 Debaryomyces ha...
Q753K6        99 EHKVKAINDFVEn----------rGNLAVKLVGHSIGAYMAQKVVVhpALRVn------------------VEMVGLLTP 150 Eremothecium go...
Q6FKU7        94 QHKIDIINK-----------INNDPNRELVIMGHSVGAYIAQHVVSspDLVGr------------------VSKLGLITP 144 [Candida] glabrata
Q0UFS1       165 TVVDLARSESGMKAAPFvk-nSNFVVFLSVIAGFIs-----MLLPLSLLT------KLIASVMSFPQD------------ 220 Parastagonospor...
Q00TT1       188 FLHVNRRSALQRALGVV-----TRLNFLAHAIGGAldg-lkKAVPFVRAA------LLRRTVTKNMDA------------ 243 Ostreococcus tauri
Q0WPD9       146 FLTLNQQSTKQSLIGKL-----AASSVLSATASFLia--slRLLPMSAAR------LLVSKSIGASWSd----------t 202 thale cress
Q0CD92       175 TVVDIAKSPSGQKLT------------LALVAGLLvrv-lvALVPHSVLR------SLVSFYM---GSpp--------dg 224 Aspergillus ter...
XP_001274264 183 TVMDIAKSPSGRKLTRL----LCVVPQLALVVGFLarv-lvALLPASWLR------GLIRVVM--GSAmp--------en 241 Aspergillus cla...
Q0UDR2       158 TIIQMADAENEGVADYF-----FRIPGFPTILGALvk---iPTFPLSLS--------VISWIACKVGNap---------h 212 Parastagonospor...
Q6C1F7       129 TVKDIAKSPRGSYFTAMdkriGYYAPSIVFTAVRVanw-ipGFVPFVASRvssrgaMLPHTAAGDAQDpseg-----nmg 202 Yarrowia lipoly...
Q6BXR7       149 TIIDIGRSNSGQIITKM----FAYLPIIQ--IAIYlsvlinSLFPESFVK------FVVKNVVIDKSSstreesqesien 216 Debaryomyces ha...
Q753K6       151 TIIDIHRSPKGVQLTRI----SEWFPRFYEYVSIVdrvlleWLLPATWIS------WLARKIIGGSDEc----------- 209 Eremothecium go...
Q6FKU7       145 TIRDIHKSSHGLIFTRV----FNYISNVNEYLSFIssnifnKLIPAYWTK------LLISFAMGCSFDey---------h 205 [Candida] glabrata
Q0UFS1       221 AAHTTASFVKSPHGVLQALHMARDEMFQIDTDIWDediWGAAADAPvskhphprptLRFLFAKKDHWVADETRDQLIRTR 300 Parastagonospor...
Q00TT1       244 VAAEITGAWLRWQSLINMVFMGRTEFVALVRPIDEcelIASANAPGr---------FAALYAHDDHWAPLHQRDAL---- 310 Ostreococcus tauri
Q0WPD9       203 AVQATCTHLRQYHTMRNVLFMAKSEFRELAAEPDWd--FMRENQSK----------LAFLFGIDDHWGPLQLFEEISKQA 270 thale cress
Q0CD92       225 AVDTTTAFIKSVRGVRQALHMAADEMQTITSDQWNddvWGMSTVQDpv------srLFFYFGRNDHWVAERTRDEIIELR 298 Aspergillus ter...
XP_001274264 242 AVETTAAFVQSKTGVRQALHMAADEMRTITADKWSddvWGVSTADEpl------arLVFYFGRNDHWVAERTRDEIIELR 315 Aspergillus cla...
Q0UDR2       213 VAQAFAEFVKGPHAVRQTMHLLRDSCQEVGEDKWTekiWGAANQAEnea-----vpLKLYFAENDGWVSRSARDALIASR 287 Parastagonospor...
Q6C1F7       203 AYDAVTRYATNPRMVRQTVELAKEEMRAIASDPEP----------AaisgfwktlpIFGFFAKDDHWVAEETRKELFEEF 272 Yarrowia lipoly...
Q6BXR7       217 STIGALKIFRSKNIIKQALNLAKEEMKTILKDDEFndwFFKGLPSKyd------irIWAYFAHTDHWVHDTTKDYILARY 290 Debaryomyces ha...
Q753K6       210 VLQSAEKLVKNPSYVRQALGMAQLEMHQVRNQWDFqeeFIKTCQERrs-------sLWLLFSGHDHWVHSDTMKDIVEFY 282 Eremothecium go...
Q6FKU7       206 IILGTFLLLTQRETLRQVLGLAAHEMLEIRDDWAFqenLLTKCKDNgt-------kLWLLFSDNDHWVSQHTQAELIKFL 278 [Candida] glabrata
Q0UFS1       301 GRfsygdevevegpeswkPVMEV---DEtEGWVHSFC 334 Parastagonospora nodorum SN15
Q00TT1       311 ------------------EALGVdvsTVeDDVRHDFV 329 Ostreococcus tauri
Q0WPD9       271 PH----------------TSLSI----ErEGHTHGFC 287 thale cress
Q0CD92       299 GQap------------dgPKMVV---CE-EGLPHAFC 319 Aspergillus terreus NIH2624
XP_001274264 316 GRve------------ggPTMLV---CE-DGLPHAFC 336 Aspergillus clavatus NRRL 1
Q0UDR2       288 GRtedc---------pwkPEMIV---DG-NGIGHGFN 311 Parastagonospora nodorum SN15
Q6C1F7       273 GHlp-------------nVHFVV------KDAAHAFC 290 Yarrowia lipolytica
Q6BXR7       291 HSds-------------nKKLSFqigDMeDSITHSFC 314 Debaryomyces hansenii
Q753K6       283 EAkygt---------nadSLLRI---TIdEHISHSFV 307 Eremothecium gossypii
Q6FKU7       279 KDry------------peLLLRV---DVdKDIKHSFV 300 [Candida] glabrata
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