Conserved Protein Domain Family
NEMP

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pfam10225: NEMP 
NEMP family
This entry includes a group of nuclear envelope integral membrane proteins from animals and plants, including NEMP1 from Xenopus laevis. NEMP1 is a RanGTP-binding protein and is involved in eye development.
Statistics
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PSSM-Id: 402020
View PSSM: pfam10225
Aligned: 65 rows
Threshold Bit Score: 111.166
Threshold Setting Gi: 74869948
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_003554045        152 TVAIEED-FQQWRLVCLAVGLILLL--LAPTVSRWVPFYYSTSMAIGI-FLVIIILLFQGMKLMPTgrKNIFYLTIYGSV 227 soybean
XP_009104989        140 TISVTED-FQQWRILCLVVGLVVIL--AAPVVSSWLPFYYTSSMAVGV-FLVILIIIFQVMRLLPTgrKNVMYLAFYGSV 215 field mu...
Q9SHQ6              138 TVNVTEE-FHQWRIFCLVAGLIVIL--LAPVVSSWLPFYYTSSMAVGV-FLVVLIIIFQVMRLLPTgrKNVMYLAFYGSV 213 thale cress
Q84ST1              188 SISIQEE-FQKWRLACLGIGFILLF--LSPIVSKWAPFYYSSSMALGV-LLVVLIVLFQGMKLLPMgrKSLFYLTIYGSV 263 Japanese...
XP_006847949        123 TISAEEE-SHPWRLAFLAFGLVVLL--LAPYVSKWVPFYYTSSMLLGI-IVVILILLFQGMKLLPTgrKNAFYLALYGSL 198 Amborell...
ERN18605            132 EVSIEEE-FKLYRLFFLTMGLLMMA--LAPAISECVTFYYGTAMAIGI-MLVILIVLFQGMKLLPTgrKRSLAIFLYGSI 207 Amborell...
EEF37112            156 ELSIEEE-FYLYRVIFLILGIVMLS--VASALSKSLAFYYSSAMAIGI-ILVTLVVLFQGMKLLPTgrKNSLAIFVYSSL 231 castor bean
Q9FJW2              154 EVSAVEE-LFMHRIVFLLLGAVLLA--SASTLSQSLAFYYSSAMAVGI-ILVVLLVLFQGMKLLPTg-rSSFALFIYSTL 228 thale cress
XP_015690222         32 VVSTEEE-FLLHRVVFLLLGMVLMV--VAHTLSESVVFYYGGAMTIGI-FLVILIILFQGMKLLPTgrKSSLAIFAYSSL 107 malo sina
WGS:AAPU:GI11225-PA  65 NLTLLQDrCDTERVARFTLGFIMWLveVATSLSESLMCVYSVAALMGIhLASVVVVCVALFYHGDR-------------- 130 Drosophi...
XP_003554045        228 vGAGSFLLHQFSLILNSIFQSLgmseemhnpvAVFVILGIILAGaalgyliVRRFVIS------KEDGSV-DAGVAQFVK 300 soybean
XP_009104989        216 vGAGSFILHQFSMMVDMILVNFglsedmyspvAILVLVGIAITGaafgfwtVRKFVVS-------KDGGV-DASVAQFVK 287 field mu...
Q9SHQ6              214 vGAGSFILHQFSMMVNMILVNFglsedmynpvAILVLVGVVITGaafgfwtVRKFVVS-------KDGGGvDASVAQFVK 286 thale cress
Q84ST1              264 vGVGSYAVHYFSTLVASILENFglseemhnpvSIFLLVAIVLTGagfgywmVRRFILS-------KDGSV-DAGIAQFVK 335 Japanese...
XP_006847949        199 vGLGSYIAHYFSTVVNSILLSFgldeemhspvSIFLVVGILIAGawlgywgVRKFVLS-------EDGSV-DIGVAQFVK 270 Amborell...
ERN18605            208 vGVGSVILRHVSVLLRSMLEEMgisndmynpvAIFVMISLGLAGawlgfwgVRKLVLS-------EDGSV-DASTATFIK 279 Amborell...
EEF37112            232 vGLGSFLLRYVPGLLRSLLVEIgisedmyyplAIFLVAFVVLAGawmgfwaVRKLVLT-------EEGSV-DISTSYFVA 303 castor bean
Q9FJW2              229 lGLGGFLLRYLPGLFESLLTEMgideemytpaAIFVGAFLSLGGaffgfwtVRKLILT-------EDGSI-DVSTSLFVS 300 thale cress
XP_015690222        108 vGMTTYFLHYLSGLLRSVLVEIgiaedmhnplGVFLLVTVILAGawfgywgVRKLVLT-------EEGAV-DAGVAYFVE 179 malo sina
WGS:AAPU:GI11225-PA 131 ---KLSSIQPVSTNFKLVLEQY----------PTSVAVALVGGV-------FILVNFCqdhhslWRHGWV-----RSLFR 185 Drosophi...
XP_003554045        301 WAMRIIGSTFILQSTLDPLLAIGALISCG------AACKLISAIKwlcgWYETSnddyslqwmRGRR------------- 361 soybean
XP_009104989        288 WAMRSVAATFIFQSTMDTPLAMGAFLSAS------LLGYLISRTIhr----rKSvvtqrqwlvPAGKgrp---------- 347 field mu...
Q9SHQ6              287 WAMRSVAATFILQSSLDTPMAMGAFVLAS------LFGFLVSKT--------KSfvgkshwlvSAGErrp---------- 342 thale cress
Q84ST1              336 WAMRVVAICFVMQSTLDPLLALFALAASW------WICSVFTAYRapksMTLKQkqskastqpMYNKgsp---------- 399 Japanese...
XP_006847949        271 WAMRIIGTVCILQSSKDALLATGSLAACW------CLCSLMSCMRw-----rPRsgkrnmwhpPGNR------------- 326 Amborell...
ERN18605            280 WSIRIVSAVMILQSSLDALLATGILIFEV------IISLTARNFFmprfILDLFrylfkmlkrFVKSamaislpayffgt 353 Amborell...
EEF37112            304 WSIRILGVIMILQSSLDPLLAAEALISGI------VVSSILRRIFrlrfLRRMCksavysvrsSLHQ------------- 364 castor bean
Q9FJW2              301 WSIRIMAAVLILQSSVDPLLAGGALISVI------LMSSTLKKITrlkfLLRLFeiplnlllgIWEAirdtdi------- 367 thale cress
XP_015690222        180 WAILIISAVMILQSSLDYLFAFSALAFCT------VVKAVSRIEGtsrfLLCLSrgiskgitiFPTSy------------ 241 malo sina
WGS:AAPU:GI11225-PA 186 RFMRLLACLFIMNASNNSVFGWLCLTCLMpwpelwWLLQWLQLKLikfqRHLMPp--------SFRRl------------ 245 Drosophi...
XP_003554045        362 --------GRAEFLSKSTPKGKHWSSPKGKLWN--SPRRS-AWSDSPVRGVVSpssgissqssgtqagqnyYSTF----- 425 soybean
XP_009104989        348 ------mhGRAEFLSRPGG---------GGLWN--SARTVpSSTGSPSNGLRNvmsrssfnrripierkdyYSTY----- 405 field mu...
Q9SHQ6              343 -----imhGRAEFLSRPGG---------GGLWK--SAKSVpSYSGSPSYDVIVsspssvnrr-ipignqdyYSTF----- 400 thale cress
Q84ST1              400 ------npRQIQFLSPSKRDIGRTTSN--------SSATQyGWSNLANGGLVSptltkrvv--pdnqdedhYSTF----- 458 Japanese...
XP_006847949        327 --------TKAEFFRRTPPKMGAQKALIKASHNrqSPSNQySWSGSPTRGLVLtpsrst------sqsqnyYSTV----- 387 Amborell...
ERN18605            354 ehsrkvakHRAEFRHHNSP----------------IPGTYsSTARTLPSNPKTpd--------------tyYSTF----- 398 Amborell...
EEF37112            365 -----------------------------------LSVTPsGLSRTPQHQLSDsd--------------vyPSTF----- 390 castor bean
Q9FJW2              368 ---psvpgYLHDFMQK-------------------SPDASgFRNRVTSASPSGginngmres-ppsesdtfPSSF----- 419 thale cress
XP_015690222        242 -------eDFGEEYSSMNGSHEDGFTKLGGEYQrcTPKRNsLRSRKTLSQGHDtd--------------syYSTF----- 295 malo sina
WGS:AAPU:GI11225-PA 246 -------lSEREFEAQAGYETQRALSEMRQRLRtaSPD---WEQLAQLQAPQQ------------------FAQFissgi 297 Drosophi...
XP_003554045        426 HKTR 429 soybean
XP_009104989        406 HRTP 409 field mustard
Q9SHQ6              401 HTTP 404 thale cress
Q84ST1              459 HNIQ 462 Japanese rice
XP_006847949        388 HKDP 391 Amborella trichopoda
ERN18605            399 HTTP 402 Amborella trichopoda
EEF37112            391 HATP 394 castor bean
Q9FJW2              420 HKTP 423 thale cress
XP_015690222        296 HTTP 299 malo sina
WGS:AAPU:GI11225-PA 298 HEpd 301 Drosophila mojavensis
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