8AGB,6S7O


Conserved Protein Domain Family
Ost4

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pfam10215: Ost4 (This model is not part of the current CDD release)
Oligosaccaryltransferase
Ost4 is a very short, approximately 30 residues, enzyme found from fungi to vertebrates. It is a member of the ER oligosaccaryltansferase complex, EC 2.4.1.119, that catalyzes the asparagine-linked glycosylation of proteins. It appears to be an integral membrane protein that mediates the en bloc transfer of a preassembled high-mannose oligosaccharide onto asparagine residues of nascent polypeptides as they enter the lumen of the rough endoplasmic reticulum (RER).
Statistics
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PSSM-Id: 519245
Aligned: 49 rows
Threshold Bit Score: 35.1457
Created: 15-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
8AGB_B         1 MISDEQLNSLAITFGIVMMTLIVIYHAVDSTMS 33  brewer's yeast
XP_002428412   1 MITDIQLAIFANALGITLFLLVVIYHYVAANYS 33 
A1Z7U3         1 MITDVQLAIFSNVLGVFLFLLVVAYHYINANTG 33  fruit fly
B0BLS0         1 MITDVQLAIFANMLGVSLFLLVVLYHYVAVNNP 33  Norway rat
Q6BEV3         1 MISDVQLGIAANILGIAMLMLVVLFHYLNANQK 33  Caenorhabditis elegans
XP_019079527   1 MIDDQDLGFFANFLGIFIFVLVIAYHYVIADPK 33 
XP_014621343   1 MIDDETLGAIANFLGIFIFALVIAYHLVTADPK 33 
Q8L986         1 MFDDQDLGFFANFLGIFIFIMVIAYHFVVAEPK 33  thale cress
Q54V54         1 MITDTQLTLLSNTLGATIFLLIVYYHYVATKTV 33  Dictyostelium discoideum
6S7O_B         1 MITDVQLAIFANMLGVSLFLLVVLYHYVAVNNP 33  human
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