8D8K,6YW5


Conserved Protein Domain Family
MRP-S28
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pfam10213: MRP-S28 (This model is not part of the current CDD release)
Mitochondrial ribosomal subunit protein
This is a conserved region of approx. 125 residues of one of the proteins that makes up the small subunit of the mitochondrial ribosome. In Saccharomyces cerevisiae the protein is MRP-S24 whereas in humans it is MRP-S28. The human mitochondrial ribosome has 29 distinct proteins in the small subunit and these have homologues in, for example, Drosophila melanogaster, Caenorhabditis elegans, and in the genomes of several fungi.
Links
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Statistics
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PSSM-Id: 519243
Aligned: 17 rows
Threshold Bit Score: 137.892
Created: 15-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
8D8K_Y 171 EY--KRPsPE-SHPVTYRYTSYVGEE----HPN-SRKVVLSVKTKEL-GL-EEKSLHKFRILARSRYDHT--------TD 232 brewer's yeast
Q09705 103 SF--KKP-AD-SQIFRFESDVQMSSF----EKM-NPKVVVTFKVTNIpLL-EEKQRHVLRLLVGPRYNPE--------ED 164 Schizosaccharomyces p...
Q6C9T8 244 PFdvKEA-DKkASPLTFKYTSYTGEE----ADE-EAKVVCYFDPANL-GL-SDKGLHKFKLLSGQNYDAL--------TG 307 Yarrowia lipolytica
Q6BHR9 152 EY--KPE-PTkDSPIKLSFNSDFSDGs---NSL-NRKVTLLCNIEDL-NL-NEKQQRKFKILATNRFNHH--------TN 214 Debaryomyces hansenii
Q5AI30 149 PY--TPR-PRtEAPIRLTYNSDFTDDtssaH---NRKVALKVSLRDL-NL-NPKQQHKFKVLAGDKFNHD--------ED 212 Candida albicans
Q750S9 156 EY--RPP-SRkTQPVLYRYTTYIGEE----HPN-SRKVVLSVLTADL-GL-NEAQLHKLRLLARTRYDHT--------TD 217 Eremothecium gossypii
Q6CQD0 156 EY--KRP-STkTHPVAYRYTTYLGEE----HPN-SRKVVLSVKTSDL-GL-EQRELHKLRLLAKTRYDST--------TD 217 Kluyveromyces lactis
Q03976 171 EY--KRP-SPeSHPVTYRYTSYVGEE----HPN-SRKVVLSVKTKEL-GL-EEKSLHKFRILARSRYDHT--------TD 232 Saccharomyces cerevis...
Q6FVM5 158 EY--KPP-SA-SDVVTYKYFTYVGEE----HPN-SRKVVLSLKTESL-GL-EPRALHKFRVLARTRYDHE--------TD 218 [Candida] glabrata
Q5KKI5  92 KF--TPP----TAPIRLTSTIDLARP----DSRyHTKCVLLVPIAAL-PLsTPEAVHRFKLLAGPRWTPGkpgrnefiKD 160 Cryptococcus neoformans

8D8K_Y 233 --------IFKMSSDKFEHASQNARYLHDILQRLLAESKDL-TeDDFSDVPLDTRHTIAKSLRKkkr----dyEFPEHWK 299 brewer's yeast
Q09705 165 --------LVRISSDKYSSALQNKYHLIKILTSLIEESKRN-A-EKFSHVPLNTGHWKYKKCDK---------RMPQEWL 225 Schizosaccharomyces p...
Q6C9T8 308 --------QCKFASKRHPSAPENKHYLLTQILKLKTEAEQ--G-DSFEDVPLDTRHARNKAERIakrdryrlaKFPEEWN 376 Yarrowia lipolytica
Q6BHR9 215 --------SIKFSSNQHAEATQNARHLVSIFNRLLEASKDL-S-DDFSDIPVDTRHMHAKKAAP---------SFPESWK 275 Debaryomyces hansenii
Q5AI30 213 --------TFQLKSERYPEAAQNVNWLVDTFNKLLTEAKDLsK-DDYSDIPLSKSHMKILAKKAv-------pSFPEHWK 276 Candida albicans
Q750S9 218 --------ILKMSSDRYEHAAQNARYLADKLQALINEASDL-T-DDFSDVPLDTRHTEARLARKnkk----ipEFPESWK 283 Eremothecium gossypii
Q6CQD0 218 --------TLRMSSDRYEEPAQNAKYLNSILLELLKEAKDL-K-DDFADVPLDKRHIIARQLRKkkr----gyEFPEEWK 283 Kluyveromyces lactis
Q03976 233 --------IFKMSSDKFEHASQNARYLHDILQRLLAESKDLtE-DDFSDVPLDTRHTIAKSLRKkkr----dyEFPEHWK 299 Saccharomyces cerevis...
Q6FVM5 219 --------LFKMSSDKFPEAQQNAKYLGDILKRLLQEAKDLsK-DDFSDIPLDTRHTIAKNLRKkhsrrlrtiEFPEEWK 289 [Candida] glabrata
Q5KKI5 161 ensdgengWIKVSEERFESARQNRRSASDILERLVNAANDReS-PLPADLPIDTRHLLARHRKKrsr----qnTF--KWA 233 Cryptococcus neoformans
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