5GUP


Conserved Protein Domain Family
ESSS
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pfam10183: ESSS (This model is not part of the current CDD release)
ESSS subunit of NADH:ubiquinone oxidoreductase (complex I)
This subunit is part of the mitochondrial NADH:ubiquinone oxidoreductase (complex I). It carries mitochondrial import sequences.
Links
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Statistics
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PSSM-Id: 519227
Aligned: 17 rows
Threshold Bit Score: 82.6298
Created: 15-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
5GUP_e        22 LPAARVRWESGS-----------------SRAVIAPSALVGKRPP-----EptirlQEDPDPEDENLYEKNPDSHGYDKD 79  pig
1_pfamImport   1 LQAARVRWESSS-----------------SRAVIAPSAVAGKRAPaptvrW-----QEDPEPEDENLYEKNPDSHGYDRD 58 
XP_040222408  19 HSLRSARLISSSqknrdaatldvskkaaaSSSGAAASSVG---------------------------TGRNWVSYGFDRK 71 
XP_049541898  19 HSLRSTRLISSSqknrdaa---tidipkkDTTTATATAAA---------------------------TNKNWVSYGFDRH 68 
XP_005805830  16 VSVLSTRFVSQS-----------------KADSAISSTAVTDPYE-----P-----VNQSGHGEVSPFAKNPDFHGFSTD 68 
Q1LYN0        18 SSALGSRFVSQT-----------------PQSSASGASVPADLRPfa-ppL-----QDSHGHAEVSPFDKNPDFHGFHHD 74  zebrafish
XP_006625337  18 GPVSGARLVSQT-----------------RSPAAAESATVSDLKPa----E-----HKAVKSAPVSMYDKNKDYHGFHSD 71 
Q4D581        32 WNQKMARAAFRRskfrrlawgdgdpypytPRAT-----------------------------------------FRYQWD 70  Trypanosoma cruzi
XP_054120699  16 RTPQTSRTFSTQsglr-------------------------------------------------------sadHGNHYD 40 
XP_002831612  22 LPAARVRWESSF-----------------SRTVVAPSAVARKRLPepttqW-----QEDLDPEDENLYEKNPDSHGYDKD 79 

5GUP_e        80 -PIV-----------DLWNMRVVFFFGFSIVLVLGSTFVAYLPDYR----------MQEWARREAERLVKYR-EANGLPL 136 pig
1_pfamImport  59 -PVT-----------DVWNMRVVFFFGFSVVLVLGSTFIAYLPDYRcmgcprewdgMQEWARREAERLVKYR-EANGLPI 125
XP_040222408  72 dETN-----------DRSAMNASFFFTVTLCLVLGSAYWAYVPDPQ----------LQDWAQREAYLELRRR-EAAGLEP 129
XP_049541898  69 dEAE-----------DRSATHASFFFAVTLCLVLGGAYWSYLPDPQ----------LQDWSQREAYLELRRR-EAAGLEP 126
XP_005805830  69 -PVE-----------DERNMKVGFFLGISVALVIGGTFIHYLPDHG----------MRKWARREAERLIRLR-EKDGLPL 125
Q1LYN0        75 ePIV-----------DEWNMKLAFFFSISLVIVVGSTFIHYLPDHG----------MRQWARREAERLIVQR-EAAGLPV 132 zebrafish
XP_006625337  72 -PHV-----------DKWNMRAAFFFGISVAIVIGSAFIHYLPDHG----------MRLWARREAERVIKQR-EAQGLPV 128
Q4D581        71 ---------------DWPLWEKIWHLAIGIIGVEFSVWAYYSKLNS----------RMDWAREEALRRMRLRrEAQELMI 125 Trypanosoma cruzi
XP_054120699  41 pPSGwlfgvkpgekyVKEGWENIWYFGFIGSLVAAGVAYVFKPDTS----------IQTWALEEARRRL----EAEGILE 106
XP_002831612  80 -PVL-----------DVWNMRLVFFFGVSIILVLGSTFVAYLPDYR----------MKEWSRREAERLVKYR-EANGLPI 136

5GUP_e       137 MESNC 141 pig
1_pfamImport 126 MESNC 130
XP_040222408 130 ISKDF 134
XP_049541898 127 ISKDF 131
XP_005805830 126 IQENY 130
Q1LYN0       133 LTENY 137 zebrafish
XP_006625337 129 MDEYY 133
Q4D581       126 LEGEK 130 Trypanosoma cruzi
XP_054120699 107 DPEKA 111
XP_002831612 137 MESNC 141
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