XP_015203371  10 VGKWEVVKKGKKPNIAGK-----KQPDKK--SAGRKALSesnmp---kidpAPPLKMSETIYE--GFERLGKKLNKEQVP 77 
1_pfamImport   1 GGKWEVVKKGKKNSSGGGsgggkNTSDKKpgGGGRKALGesnqgsrdtntpSAPIVMSATLYD--GFEKMAKKQNKEQVP 78 
4_pfamImport   1 FGKWEVVKKGKKSNTSGGg---kSATDKKmgSGGRKALGesnqss-rrnftNVPIKMSETLFN--GFDRIGKKQNKEQVP 74 
XP_011490299   8 AGKWEVVKKGKKSSNSGG--------EKRagSGGRRALGesnqe--adrrkSAPIKMAETLYG--GFEKIGKKHNKEQVP 75 
Q6NUQ4         8 VGRWEVVKKGRRPGVGAG-------AGGRggGRNRRALGeangv--wkydlTPAIQTTSTLYEr-GFENIMKRQNKEQVP 77  human
2_pfamImport   1 SGGWELVGRNKKDKNNGKinkltKAEKKKfiENAPKVED------------FLPLSQVKTLYDnlDNNKENKKPPKE--K 66 
XP_011147586   3 SGGWELVGK-KKDRTNGKvnkltKAERKKfiENAPKLED------------FLPLSQVKTLYDnlDGNKETKKSPKA--K 67 
XP_011060329   3 SGSWELVRR-KKDRGNDKsnkltKAEKKKfiENAPKVED------------FLPLSQVKTLYDnlDGNKENKKPAKAQGK 69 
XP_002001979   5 SNQWEVVSKSRKQKNLEKkv-taHTEQKRiaAQLPKLEE------------LLPTQQYRNLFAnnNINNSNTNN-KSDSP 70 
XP_002014306   2 SDQWEVVTKSRKQKNLDKkv-taHTEQKRiaAQMPKLEE------------LLPTQQYRNLF------GSTNNNSISNSP 62 
XP_001963222   2 SDQWEVVTKSRKQKNLDKkv-vaHTEKKRlaAQLPKLEE------------LLPTHQAQ-LFA-----SSNNNNYKSSSP 62 
XP_002036605   2 SEQWEVVTKSRKQKNLDKkv-saHNEQKRiaAQLPKLEE------------LLPTQRYRNLFGssGTSSSNNNNSKSHSP 68 
XP_005990959   9 AGKWEVVKKNKKSNNS-----------EKksGGSRKALGesnmp---kidpAPPLKTSDTIYEl-GFDKVAKKQNKEQVP 73  coelacanth

XP_015203371  78 PVsaPEPQQKK-ASSgKPTKKS--------------PGNDGGQKSGKfKTLEDAMKAFDVAELQQELEKSQNLFPENPSV 142
1_pfamImport  79 PP--AESENKKpSTS-KPPKKP--------------HSSSAAPSPVH-KTLEDAFKSLDVGDLKQQLARSQTLFPENPSV 140
4_pfamImport  75 PA--TEPHHPRkAPApREAKAS--------------APSSRVTSGTH-KNLAEAFKALDLGDLRQQLAHSQTLFPDNPSV 137
XP_011490299  76 PA--AEPQSKKpSSSnKPPKKS--------------PSNTSTPAAC--RTLEEAFKALDVADLKQQLARSQTLFPDNPSV 137
Q6NUQ4        78 PP---AVEPKKpGNKkQPKKVA--------------TPPNQNQKQGRfRSLEEALKALDVADLQKELDKSQSVFSGNPSI 140 human
2_pfamImport  67 ENktKENEEKKkQ----QKQQS--------------EKKKHEPKEKPpKSIKDALNMINVAELHNVFINSQTRFPEAPLI 128
XP_011147586  68 EHkmKENEEKKkQQQqKQQQQA--------------EKKKQEPKEKPpKNIKDALNAIDIKELNNVLATAQARYPEAPLI 133
XP_011060329  70 EHktKENEEKKkQHQ--KQQHV--------------EKKKSEPKEKPpKTVKDALNAIDPQELDELLATAQVRFPDAPLL 133
XP_002001979  71 AKstSSAASASsKSKsPRKTNAtaaks-----satdVAKKPPKQAAKaRTLEQAMKQITPDDFAAQLEQVKISCPGSQLR 145
XP_002014306  63 AKssSSASSSK--NKsPIKKNAiktvgsggnsgggsTKKQMPAPLAKpKTLEQALKHITPDDFAAQLTQVKLSCPGSELR 140
XP_001963222  63 AKssSSGSSTSk-TKsPAKKNTgkna------atagAAGAKKPTSTKpKTLELALKNITPDDFSAQLEQVKLSCPDSELR 135
XP_002036605  69 AKssSSASSSSkANKsPVKKHTakn--------tstQKRTTSSAASKpKTLELALRNITRDDFAAQLEQVKLSCPGSELR 140
XP_005990959  74 PAftSEEQQQKkPNMgKQAKKS--------------ASADAGQKPYKyKSLEDALKDIDLTELQQQLEKSQSLFPANPSV 139 coelacanth

XP_015203371 143 WVKDLAGYLNYKLQAPESDPTLSNHPYDYPYSLASKELKHVIKVLLGKCSDS-LQDFFDHCIYTMLREMDRs---sGEAL 218
1_pfamImport 141 WVKDLAGYLNLNLTAPETEPTLSSYAHDYPYCLSGKELKGVIKGLIGRCSDI-LPDFFDHCVYTMLREMDRqtaspGEPL 219
4_pfamImport 138 WFKDLAGYLNLYLTAPDTGPTLSSHTHDYPYCLAGKELRGIIKALVGRCSHI-LPELLDYCVYTMLKELDRq---sGEPL 213
XP_011490299 138 WVKDLAGYLNQHLAAPDSEPTLSSFPYDYPYCLTGKELRAVIKSLLGRCSNI-LPDFFDHCVYTMLRELDRq---sGEPL 213
Q6NUQ4       141 WLKDLASYLNYKLQAPLSEPTLSQHTHDYPYSLVSRELRGIIRGLLAKAAGS-LELFFDHCLFTMLQELDKt---pGESL 216 human
2_pfamImport 129 WLKDLAAFLNIKIPVDKEDVIFSGKSKDYPLSIIPKSISSILEKAIDMAGKQtVQLFYENTLTNMATDMVK-----GSPV 203
XP_011147586 134 WLKDLAAFLNVKVPIDKEDAIFSGKPKDYPLSLVPKAISSTLEHVVEMAGQQsAQHFYEITLTSMATDMVK-----GIPV 208
XP_011060329 134 WLKELNAFLNIKIPINKEDAIFSGKPKDYPLSLVPKTISSILERAVEMTGQQtIQIFYENTLTTMATDMVK-----GIPV 208
XP_002001979 146 WLSNISSYLNSRLAFD-CDPTFSGRSAQYPSNLASAALKQSILDFLRSVGETnLEYFFYSLLDSMATELNS-----GQNV 219
XP_002014306 141 WLSHIALYFNGALSYD-CDPVFSGRSAQYPSNLASAALKKSVVEFLSSVGESnLEYFFYSLLDGMTTDLNN-----NQTV 214
XP_001963222 136 WLSHVALYFNGALSYD-CDPIFSGRSTQYPSNLASHSLKYLIVEFLGSVGESnLEYFYHSLLDSMATELNN-----NQTV 209
XP_002036605 141 WLSHIALYFNEALSYD-CDPIFSGRSAQYPSNLASASLKYSIVEFLGSVGEQnLEYFFYSLLDSMSTDLNN-----NQTV 214
XP_005990959 140 WVKDLAGYLNYKLQVLEADPMLSQHSYDYPYSLVGKELKNLIRSLLGKSGDA-VEHLFDHCIYIMLRDQDKa----gESL 214 coelacanth

XP_015203371 219 HGYRVCIQAIMLDKPKIATLNLPDHLELLRSHQNRPVKCLAIMWALGQCGFTDLTEGLKVWLGIMLPVLGVKALSSFAIG 298
1_pfamImport 220 HGYRVCIQAILQDKPRIATQNLPEYLELLRSVQNRPMKCLTIMWALGQAGFYDLSQGLRVWLGIMLPVLGLKALSSYAIA 299
4_pfamImport 214 HGYRVCIQAILQDKPKIATQNLPMYLELLRSVQNRPVKCLTIMWALGQAGFCDLSQGLRVWLGIMLPVLGVKALSAYAIA 293
XP_011490299 214 HGFRVCIQAVLQDKPRIATQNLPEYLELLRSVHNRPAKCLTIMWALGQAGFYDLSQGLLVWLGIMLPVLGVKSLSAYAIA 293
Q6NUQ4       217 HGYRICIQAILQDKPKIATANLGKFLELLRSHQSRPAKCLTIMWALGQAGFANLTEGLKVWLGIMLPVLGIKSLSPFAIT 296 human
2_pfamImport 204 FGHKIFLQLLAYINPEMTIVNISKLIRVKNSYQNRKNIGLSILWAISQAGRKNLAVGLKVWHEVMSPMLEIKSYCSYVAQ 283
XP_011147586 209 VGHKIFLQLLAHINPEMTAANIPKLITIRSSYENRKNVGLSLLWAWSQAGRKNLAVGLKIWHELMSPMLDMKGYANYVVQ 288
XP_011060329 209 IGHKIFLQLLAHLNPEMTAANILKLINIRNSYENRKNIGLSLLWAWSQAGKKNFAVGLKIWHEVMSPMLETKSYASYVVQ 288
XP_002001979 220 VGYKFVLQLIGQNWPAICSHNMAKTALLRNSYQNRSNICLSILWAIGQGGHQNLTEGVKVWQNLMLPNLELKSLSKFVVE 299
XP_002014306 215 VGYKFMLQLIGQNWPSICSKNFAKTALLRNSYQNRSSICLSILWAIGQGGYRSLNEGVKVWQNLMLPNLELKTYSKFVVD 294
XP_001963222 210 VGYKLLLQLIGQNWPGICAKNLAKTALLRNSYQNRSTICLSILWAVGQGGYQSLNDGVRVWQNLMLPNLELKQYSKFVIE 289
XP_002036605 215 AGYKLILQLIGQNWPNICSRNLAKTALLRNSYQNRSNICLSILWAIGQGGYQSLNEGVRVWQNLMLPNLELKQYTKFVVE 294
XP_005990959 215 YGYRICIQAVLQDKPKIATMNLPKYLELLRSHQNRPLKCLSIMWSLGQAGFADLTEGLKVWLGIMLPVLGVKSLSSYAIG 294 coelacanth

XP_015203371 299 YLERLLMLHANLTKGFGI-MGPKEFFPLLDFAFMPKNA--LIPSLQDQLRRLYPRLKVLAYGAKPeCTLHTYFPSFLSRA 375
1_pfamImport 300 YLERLLLLHANLTKGFGI-MGPKEFFPLLDFAFMPKNA--LTSSLQEQLRRLYPRLKALAFGAKPeSTLHTYLPSFLSRA 376
4_pfamImport 294 YLERLLLLHTNLTKGFGI-LGPKEFFPLLDFAFMPKNA--LSPSLQEQLRRLYPRIKVLSFGAKPeSTLHTYLPSFLSRA 370
XP_011490299 294 YLERLLLLHANLSKGFGI-MGPKEFFPLLDFAFMPKNS--LSPSLQEQLRRLYPRLKVLAFGAKPeNTLHTYLPSFLSRA 370
Q6NUQ4       297 YLDRLLLMHPNLTKGFGM-IGPKDFFPLLDFAYMPNNS--LTPSLQEQLCQLYPRLKVLAFGAKPdSTLHTYFPSFLSRA 373 human
2_pfamImport 284 ILNNLVFGHETFHD-----LKPELYLDIVENICSGKLN--VSASIGREINNSIEKLRSILFKNKN-INYVKLFEMLITKI 355
XP_011147586 289 ILNDLVFGHDNVRD-----LSLDLYLDIIAETYSNKFSn-QPANLAVEISTSIDKLRSIVFKSKD-ISYTKLFEMLLGKV 361
XP_011060329 289 ILNDLVFGHDNVHD-----LSLDLYLSIIMDTYSQRFQniQPANLGKDLSASIDRLRSILFRNKD-ICYTKLFEMLMGKV 362
XP_002001979 300 HIERVLNAAAARK-GEALlINQQEFFDCYNALNGNYNN--FSKEQQASLKRSAKQLLQLYI-ASP-VKQANIFLTLLRLI 374
XP_002014306 295 YIERVLNAAAVGTSEDILlLNQNEFFATYNALNATYNN--LPKELQQSLKRSASQLLQKYI-SSP-VKHANIFLTLFRDI 370
XP_001963222 290 YIEKVLKEASARKLDDPLlLNQQEFFAAYNALNATYIN--LPKEQQQSLKRSARGLLEIYI-NSP-VKHANIFLTLFRDI 365
XP_002036605 295 YMERALNAAAARKTADPLqINQQEFFATYNALNAPYNN--LPKEWQQSLKRSARLLLQNYI-NSP-VRHANIFLTLLREI 370
XP_005990959 295 YLDRLLMMHPNLTKGFGM-IGPKDFFPVLDFAFMPNNS--LSASLQEQLQHLYPRLKVLAFGGKPeSTLHTYFPSFLSRA 371 coelacanth

XP_015203371 376 TPHCPEDMKKELLKSLTECLSLD--PQSLSVWRQLYTKHLSQSSLLLNNLLQSWNTLPP-KLQ-KSLQETVQSFKVTNDE 451
1_pfamImport 377 TPHCPDEMKRELLSSMTECLCVD--VQSLGVWRQLYTKHLPQSSLLLNHLLKSWKSLPPkKLR-KNLEETVQSFKVTNDE 453
4_pfamImport 371 TPHCPEDMKKELLGSMTECLCVD--VQSLGVWRQLYTKHLAQSSLLLKHLLKSWNQLPP-KLR-KNLEDTVQSFRVTNEE 446
XP_011490299 371 TPSCPDDMKRELLSSMTECLAVD--VQSLGVWRQLYTKHLPQSSLLLNHLLKSWNALPP-KLR-TNLEETIRSFRVTNEE 446
Q6NUQ4       374 TPSCPPEMKKELLSSLTECLTVD--PLSASVWRQLYPKHLSQSSLLLEHLLSSWEQIPK-KVQ-KSLQETIQSLKLTNQE 449 human
2_pfamImport 356 TQKIHANYRDELIKALVTCLATD--SLCFSVWKSIYAKNLYQSHLILSYIDSKWHVLHA-TLEiKCLKETCIVFQTINER 432
XP_011147586 362 TPKSYTDYRCEIIKALADCLVTE--PRCFAIWGSIYPTYLYQSSLLLQYIDANLPSLQP-QLRtKHFKETLAIFQNSNEK 438
XP_011060329 363 SQKLDLNYRNELIKVLADCLVTE--PVCFTIWNSIYTKNLYQSSLLLSYIETNLPSLQT-KFKaKHFKETLGIIQNNNEK 439
XP_002001979 375 NS----NNQRTEIEGCISCLLSSgaDDCFKVWRMNYKKQQIPSCILLMAIVNDWEGPAKaLAQsPAFLSFLQSVKHLNIE 450
XP_002014306 371 TTV---NKPINEIEGCISCLLSSggDDCLKVWRMNYKKQQLASLLLLQAIDKDWETSTNlLAKsPVYHTFLHDLRLLNEE 447
XP_001963222 366 SAT---SKNNNEIEGCIRCLLSSgrDDCLRVWRMNYKKQQVPSLLLLRAINENWAGSTKdLALsSAYHSFLQDLRNLNDE 442
XP_002036605 371 SAG---SKQTNEIEGCISCLLSSgrDDCLRVWRMNYKKQQLPSLLLLKAIDDNWTTSTHeLATsTVYHSFLQDVAALNEE 447
XP_005990959 372 TPNCPEDMKKELLNCMSECLNMD--PLSFSVWRQLYTKHLSQSSLLLNHLLESWDSTSR-KMQ-KSLQETVHSFKVTNEE 447 coelacanth

XP_015203371 452 MRTSANS--QDLKDCSSLCNRLQLKMKGHG----------------FPWSRLLLALVVFASGFVVHDVRSH--GSFKASS 511
1_pfamImport 454 MKDAVES--PELQECNSLCQNLQVKMRGRG----------------FPWSKLLMVLLVFVAGFIAHDVRSH--GSFADST 513
4_pfamImport 447 MRGAAGS--QDLQDCNNLCQNLQVKMQAGG----------------FPWSKLLLVLLLFAASFMAHDIRSH--GAFAGST 506
XP_011490299 447 MKEVVES--EELQECNKLCQNLQVKMRGNS----------------FPWVKLLLVLSVFAAGFIAHDIRSN--GSVAGSS 506
Q6NUQ4       450 LLRKGSSnnQDVVTCDMACKGLLQQVQGPR----------------LPWTRLLLLLLVFAVGFLCHDLRSH--SSFQASL 511 human
2_pfamImport 433 CKKTKDE--GLANNCSKLCKVLLLKMTASAnk-------------kFPWKKGIILLLLFISVILGYDIYKH--DDFKASN 495
XP_011147586 439 WKKVKDE--NLANTCKVTSQALLKKMTSSTrr-------------gFPWGIGSLSLLLLISAVIIYDVQKH--GSFEASQ 501
XP_011060329 440 WKKAKDE--NLALTCKKTSQALLKKMTSSSr--------------gFPWRSASLLLLLLIGAIVAYDTQKH--GSFKASQ 501
XP_002001979 451 LQSNKRKd-ICVDDLEAILKTVQEKTSAQQkknkqnaasqkkkcgcCKWTLGSIFIIALIAGALCYDTEVNgkGVFENSA 529
XP_002014306 448 LQSSKRRe-SCLDELIEVLVTVQEKSSAQQkknkqnsatqkkkcgcCKWTLGSIFIIALIAGALCYDTEVNgkGVFEKSA 526
XP_001963222 443 LRCSKKRd-STIDSLQEVLLSVQEKSTAQQkknkqnaaaqkkkcgcCKWTLGSLFIVALIAGALYYDTETNgkGVFEKSA 521
XP_002036605 448 LQGSKRNe-GHLDDLKEVLLSVQEKTSAQQkknkqnaaaqkkkcgcCKWTLGSIFIIALIAGALCYDTEVNgkGVFEKSA 526
XP_005990959 448 LSAKGQSsvQDIAACNAACNNLLHKMRGRG----------------FPWHQLLLMCLIFIVGFVMHDIRSH--GSFKASS 509 coelacanth

XP_015203371 512 CAHVLQQSGMMSVSEQAWSKISHYSQEGYSWVETNAPHYYSQAVTTLGPFLEVAWEKTKTSSAFIVEQCSVQITWIQENA 591
1_pfamImport 514 TALHLRSSGVTDVSQQAWSKVKLYSTQGFSWLETNTPHYYSECARVLGPLLEQGLEKSKTAAIFISENTTQFILWVKEKT 593
4_pfamImport 507 TATYLHKSGVTAVSQQAWSKVSVYSKQGFSWLEKNTPHYYSECVRVVGPLMDQGLETARTAGVFLSERARLLVLWVQ--- 583
XP_011490299 507 TAKYLQSSGVTAVSQQAWSKVTVYSKQGFSWLEKNTPHYYSECVRVLGPIARQAAEQSQAVGVLISEKASQLLLWLRESA 586
Q6NUQ4       512 TGRLLRSSGFLPASQQACAKLYSYSLQGYSWLGETLPLWGSHLLTVVRPSLQLAWAHTNATVSFLSAHCASHLAWFGDSL 591 human
2_pfamImport 496 TNKFLKRSGLFACGQQSWIIMQEYSYKALEFVEATSPEYYKATIETCQPYIKLTGNVYIIIKNHFLKIFDNILEYIEKNS 575
XP_011147586 502 IGIFVKTSGISKYVEKAWTTIQSYSSAGHQTIKNSS-EYYKAAVDLCVPYVKLAGDVYLVVKNISIKIYNNALVYIEKKT 580
XP_011060329 502 VGKFLKTSGILKHVEKAWTTLKFYWSAGHKAVKDSSPEYYKAVVDLCAPYIKLAGDSCLIVRNLSIKLYNNVAAYVERNV 581
XP_002001979 530 TGKVLKNAGVLPQVQRGWYVTMGAGARGYKWAEQHIPPY-------AQPAIKTGIDVWKIARNACCSAYTNALNYWRSQW 602
XP_002014306 527 TGKVLKNAGVLPHVQRAWYVTMGASARGYKWAEEHVPPY-------AEPAIKTSVDLWKLARNAAYNIIQSGKGYFNTKW 599
XP_001963222 522 TGKVLKNAGVLPHVEKTWYTVMGAGARGYKWAEVNVPPY-------AEPVVKTSVDVWKLARNAACNIFQNGKGYFSAKW 594
XP_002036605 527 TGKVLKNAGVLPHVQKSWYTVMGAGARGYKWAEVNVPPY-------AEPVIKTTGDLWKLARNAACKAYQNGKGYFGAKW 599
XP_005990959 510 SARMLQQTGVMSVSQQSWNKISHYSQEGYSWLETNAPHYYTQILTTLGPNLEVVWNKTSEAAIYITEKCSAQITWIKENF 589 coelacanth