3EU8


Conserved Protein Domain Family
Glycoamylase

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pfam10091: Glycoamylase 
Putative glucoamylase
The structure of UniProt:Q5LIB7 has an alpha/alpha toroid fold and is similar structurally to a number of glucoamylases. Most of these structural homologs are glucoamylases, involved in breaking down complex sugars (e.g. starch). The biologically relevant state is likely to be monomeric. The putative active site is located at the centre of the toroid with a well defined large cavity.
Statistics
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PSSM-Id: 401907
View PSSM: pfam10091
Aligned: 18 rows
Threshold Bit Score: 209.505
Threshold Setting Gi: 81531046
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3EU8_A        196 NFPVHGYNECLIXYILAAASPTHGVPAAVYHeGW-AqngAIVSPHKVEGIELHLRYqgGeagPLFWAQYSFLGLDPVGLK 274
WP_011993439  166 GH-WDKYAEQLMMYFLGVASPTYPVEPSVYW-S-------FQRDIGNYKDYELIYTytG---SLFTYQFSHAWIDFRKIT 233 Fervidobacteri...
jgi:Caur_3867 179 isvWDMAAEQKMIYLQAALHLDPTTARALYR-G-------FRRDKGDYRGQSIIINpgG---TLFAYQYTEAWLDVRTYR 247 Chloroflexus a...
Q7UQD9        213 PYQWDRFSELTILVLLAIGAPSSAIPPSCWN-AW------RRENVLHHQGESFVSY--P---PLFVHQYPQAFFDFRGVV 280 Pirellula sp.
jgi:Pnap_4503 190 PYRWSGYDEATLLYVLGLGSPTHPLSAESYA-AW-----TSTYEWKTIYGHELLYG--G---PLFIHQYSHIWLDLRGIQ 258 Polaromonas na...
Q21ZB9        180 AYRWEGYDEALVLYILGLGSPTHPLPQSSYA-AW-----ASTYEWKNSYGYDYLYA--G---PLFTHQISHLWIDFRGIQ 248 Rhodoferax fer...
jgi:Acry_3133 179 HYGWEGYNEAALLYVLGLGSPTFPLTPAGYV-TW-----QLTYQWENLLDRDVLYS--G---PLFTHLFSHAWIDFRGIR 247 Acidiphilium c...
Q2K2Y3        181 RWRYHGFDEAIILYALALASPTHPVPQSSYD-AF-----TSSYSWMTFGDQPYLYA--G---PLFIHLFSHAWIDFRGIQ 249 Rhizobium etli...
Q5FT68        248 PSDWKGYNEGLIIYLQALGSPTHPLPAETWK-AWtA---TYENQWGDFQGHKLLNF--A---PMFGHQYSESWIDFRGVQ 318 Gluconobacter ...
Q8P8N3        243 dHDWMGYNEAMMLYILALGSPTHGVEPDAWT-VW-Tr--tYNNDWGVYQGQEYLSF--G---PMFGHQYSHVWIDFRDIQ 313 Xanthomonas ca...
3EU8_A        275 DEY----CpSYFNEXRNLTLVNREY----CIRNPKHYKGYGPDCWGLTASYSVD--------------GYAAHGPleRD- 331
WP_011993439  234 DKS----GvNWFENSVKASLANWEY----CKEMHDKYKTLHEYSWGLTACDSPS--------------GYRGDFGapPSa 291 Fervidobacteri...
jgi:Caur_3867 248 DPD----GvDWFTNTRLASMANRDY----CVSLHERFRTYHANSWGIGCGDTPR--------------GYVVAGAppALi 305 Chloroflexus a...
Q7UQD9        281 SSD----GrNYWRNSQLAHLAQIEFqqslADQSPKRFGHYGEDLWGLTSSDSSN--------------GYRDWGGpyEDg 342 Pirellula sp.
jgi:Pnap_4503 259 DVFardkGiDYCENSRRATYVQREY----AIRNPLDFAGYGENFWGLTASDGPGsttrrikgiersffDYVARGApyGP- 333 Polaromonas na...
Q21ZB9        249 DAFmrekGiDYFENTRRATYVQQQY----AIDNPLKFAGYGKHCWGITASDGPGpetvkvkgierhflDYVGRGVpyGP- 323 Rhodoferax fer...
jgi:Acry_3133 248 DEFmrekAsDYFENTKSAIAVHREY----AERNPYGFEAYGRDFWGVTAGDGPTapemlengkdcrffGYMSRGVpyGP- 322 Acidiphilium c...
Q2K2Y3        250 DRPmmdrNwDYFRNTQVVINMQRDY----AERNPGGFVGYNRNVWGFTACDGPPptrrmrggrqpkvlGYAARGAplGP- 324 Rhizobium etli...
Q5FT68        319 DAWdrahNvDYFQNGREAAYAQRAY----AQANPGDWKDYGPNIWGLTACDGPGdaqqvydgkkrhylAYSARGAgrDYi 394 Gluconobacter ...
Q8P8N3        314 DQYmrerGiDYFLNSRRATLAQRDY----AIDNPMKWKDYGENVWGLTAGDGPQntsqeyrgeqrqfrHYSSRGAglREn 389 Xanthomonas ca...
3EU8_A        332 -------DRGVISPTAALSSIVYTPDQSLQVXHHLY-EXGDKVFGPYGFYDAFSE-TAd---------------WYPKRY 387
WP_011993439  292 nnntqhyVDGTVPPCGALGSIVFVPEIVEETVRYYY-EKVPQLWGKYGFKDAYNLdKn----------------WTSEVY 354 Fervidobacteri...
jgi:Caur_3867 306 p----pePDGTVSISNATACLPFIPDDVLAMLDYLY-REHPQSYGRYGFYDAYNL-DTvp-------------aWYSHTI 366 Chloroflexus a...
Q7UQD9        343 qaqpdrgIDGTVVPSAAGGGLAIAPEQTMRTLQYQKnTFGESVYGRYGFVNAFNP-RRg---------------WIGSDV 406 Pirellula sp.
jgi:Pnap_4503 334 -------DDGTVAPWAVAASLPFAPEIVLPTLQHFQ-DVYPQVTGEYCFRCSFNL-SFsdeaes-----dghvgWTSPYH 399 Polaromonas na...
Q21ZB9        324 -------DDGTIAPWAVVASLPFAPEIVLPAIDFLVhEVELKTGNPCGFKATFNP-TYphkrs-------nphgWVSPWH 388 Rhodoferax fer...
jgi:Acry_3133 323 -------DDGTIAPWAMLATLPFGADAALAGTRGLL-ELHPKVCHQDRFSSGFNP-TLsdg----------dggWLSTGW 383 Acidiphilium c...
Q2K2Y3        325 -------DDGTIAPWAALACLPYDRQAALDGTKALL-TTYPNLLLEGGFPGGFNP-TVqtkr---------pegWVDDRT 386 Rhizobium etli...
Q5FT68        395 ------lDDGTIAPTAVGGSIAFAPEIALPALKEMRaRYGDRIYNKYGFLDAFNP-SFadq----------ksyWVDGQQ 457 Gluconobacter ...
Q8P8N3        390 ------fDDGTIAPTAAISSIVFAPEVVIPATEEMHkRYGDFLYSSYGFLDSFNP-SFnydiplktgrmvpdrgWVASDY 462 Xanthomonas ca...
3EU8_A        388 LAIDQGPIAVXIENYRTGLLWKLFXSHP 415
WP_011993439  355 IGIDKGIELLMIENYLSGLIWDIVMKSE 382 Fervidobacterium nodosum
jgi:Caur_3867 367 YGINKGCALLMLENACTGLIWDIYTNSP 394 Chloroflexus aurantiacus J-10-fl
Q7UQD9        407 IGIDTGITLLSASNLLEEGVWQPFMQHP 434 Pirellula sp.
jgi:Pnap_4503 400 FGINLGPVVLMCENYRSGLLWRLMRACP 427 Polaromonas naphthalenivorans CJ2
Q21ZB9        389 YGLNQGPIVLMIENYRTGLLWRLMRDSS 416 Rhodoferax ferrireducens T118
jgi:Acry_3133 384 YGLDQGLLVMMIENHRTDMIWEIMRHCS 411 Acidiphilium cryptum JF-5
Q2K2Y3        387 VGIDQGLVVMTIENERSDFIWKLMRQSP 414 Rhizobium etli CFN 42
Q5FT68        458 LGIDQGPILLMLENWRSGLVWNTMKKNA 485 Gluconobacter oxydans
Q8P8N3        463 IAIDQGPILAMIANYQNEFVWNVMKKNa 490 Xanthomonas campestris pv. campestris
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