4FMT,4QPJ


Conserved Protein Domain Family
HPTransfase

?
pfam10090: HPTransfase 
Click on image for an interactive view with Cn3D
Histidine phosphotransferase C-terminal domain
HPTransfase is a family of essential histidine phosphotransferases. It controls the activity of the master bacterial cell-cycle regulator CtrA through phosphorylation. It behaves as a homodimer by adopting the domain architecture of the intracellular part of class I histidine kinases. Each subunit consists of two distinct domains: an N-terminal helical hairpin domain and a C-terminal [alpha]/[beta] domain. The two N-terminal domains are adjacent within the dimer, forming a four-helix bundle. The C-terminal domain adopts an atypical Bergerat ATP-binding fold.
Statistics
?
PSSM-Id: 401906
View PSSM: pfam10090
Aligned: 62 rows
Threshold Bit Score: 68.0186
Threshold Setting Gi: 566556909
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
4FMT_B         97 SRELEKLAQGVFA--HVRPTLDwqiEPQAMNKPSSRAVLNIAQIAASALPAGGVATVKGVaadgRFSIIADAKGPRARLR 174 Caulobacter vi...
jgi:Bind_1019  83 TGDAERVMRGLFA--EGRSTLEwhaPRVLMAKDKVKLILNLCLIAMAALPRGGVVSVTIEggetPSHIKIDAQGTNARLA 160 Beijerinckia i...
Q20YL4         92 LGDAQNMARGHLE--DDKTKIEwnlPRILLPKNKVKLLLNMLVIAQQTIPRGGVLTVEAVgegdAMGFRVAASGLNARTQ 169 Rhodopseudomon...
Q6N9C3         91 LGDAQNMARGHLE--DDKTKLTwnlPRLLLAKNRVKLLLNMLVIAQQTIPRGGTLTIDPIgegdNLSFRIVAAGINARTP 168 Rhodopseudomon...
EGP06249      104 LGEAQKMTRNHLE--DEKTKITwnlPHVLMAKNRVKLLLNMFVIAQQAIPRGGELTVDPVgegdTMGFRLRAAGTNAREP 181 Bradyrhizobiac...
Q89T59        110 LGDAQTMARGHIE--DGKCTITwnlPRLLLPKNRVKLLLNMLVVAQHTIPRGGTLTIDPVgegeTMSFRITATGHNARLP 187 Bradyrhizobium...
Q1QI40         88 LGDAQNMAKGHFE--DGKITIAwnlPRLLLPKNRVKLLLNLLVIAQQTIPRGGVLTVDPLgegeAMGFQITAAGLNARLS 165 Nitrobacter ha...
jgi:Plav_2173  86 LQDAKAVAEGLMM--GERAALTwnaPAATIGKDYVKLLLNMILIGMAAIPRGGEVAVSVDgelaKPTLRIRSTGQAARIP 163 Parvibaculum l...
WP_013948783   84 LTTAEKISRGFVGitQGKHKLTwrgAPGLVPKDKVKLLLNLIASAVTALPRGGEIDVSIGgsfeQPTFLIRCKGTGARPP 163 unclassified H...
WP_023788422   87 LGTAEQISRGFVG--DAKHKLVwhvQPGHMGKDKVKLLLNLVAVAITALPRGGEIEVRMSgtmeAPNFVVRCQGTAARPP 164 Hyphomicrobium...
4FMT_B        175 PEVLAGLKGEPLAEglGGPWVQAAYLNALVRAAGGQIAVEIGEDR 219 Caulobacter vibrioides CB15
jgi:Bind_1019 161 QHVPSLLAGAPDTGsvDAHGIQAFYTGLVAKSAGMTLDIIAEPNL 205 Beijerinckia indica subsp. indica ATCC 9039
Q20YL4        170 TNIVDMLSGAHAGs-iDAHAVQPYYTRLLAQACGFSVSLAPAGEA 213 Rhodopseudomonas palustris BisB18
Q6N9C3        169 HNIVDLLNGTQSGp-iESHGVQPYYTRLLAQACGLTVSLAPEGDT 212 Rhodopseudomonas palustris
EGP06249      182 QNVAAQLNLDNAGs-vSAHAVQPYYTALLAQACGLKVSLTAETDA 225 Bradyrhizobiaceae bacterium SG-6C
Q89T59        188 QNIAELLSGERGPa-aDAHAIQPYYTRLLAQACGLTVTLAPEGAA 231 Bradyrhizobium japonicum
Q1QI40        166 QTTADLLASGPAGa-vDAHAVQPYYTRLLAEACGIGISLAADGEK 209 Nitrobacter hamburgensis X14
jgi:Plav_2173 164 EETAKFLGGRSPDRflDARAAQPYFTGLVARSLGLSIDARMDGEA 208 Parvibaculum lavamentivorans DS-1
WP_013948783  164 QYLTDFVAGNPLa--lDAITIQAYYTWRIAPTAGMKLEILKDGAD 206 unclassified Hyphomicrobium
WP_023788422  165 QHLGEFISGENVPp-lDALTIQAYYTWRLARNANMTLAIVKDGAD 208 Hyphomicrobium nitrativorans
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap