WP_014434305   47 LTGYCFWIAYSLGLLRNDIGGAWLALIG-----VAIISVVAGRRKPGALAFsa--------lpSLRYILLFELLFLGAFA 113  Caldilinea
4_pfamImport    1 LAGWLLWMLTSLGLLRNTVLFSWLSVAF-----LAVVGAWIAYRQRKAMSAfi--------rtSWPLMLVGELLFAVAFL 67  
2_pfamImport    1 LVAYLAWLGGSLHLVPFAPTTLWTIGMV-----VLGVGGFIGWRERTTLRRiw--------heRWSALAMAEMVFLAFLL 67  
WP_013559992  990 LWSYFVWLGGS-YKIPVTRTTITGVLVL-----LIGVGMVLAWLQRKDILQdi--------reQGKHFLFVEGLFAIFFL 1055 Anaerolinea t...
WP_012874896  679 IIALGAWLGTSLGLLTY-PASLWVITIG-----FILFSLSFALVNSRSLVNil--------rsRISRIVLLEGLFLLLFI 744  Thermobaculum...
Q8TIR4         29 LVAYFSWIFSY--IWGFNRVTILISVLV-----LCLLSIGLYRKKRIFP--------------ERKILLVNELVFLTAFF 87   Methanosarcin...
WP_012874897   48 FVSWSTWYGLYLGIWDKNKGLIISVAALffisvLVAIVFFRSSFNRSLLFQ------------GWKYYLSLELIFVLAFS 115  Thermobaculum...
WP_015359094   78 ISSFIFWLLSYAKLLDITPAHCWSVTVAa---gLAVYVVFFGWKKFYRNISgii------dkdTFFWVFTGEGLFLFSLS 148  Thermoclostri...
CDE66574       70 VSGFAVFALGSFGLVPFTAPVCLITVGV-----LILASWIFGCFKVRVHAP------------EIDFLMMEEVLFFAFFL 132 
WP_012200895   89 IAGWVLWYLSSLRLLKFTRENAIITLVIcflvnLLIIGLSYYLKNRRDEKKcplndwyqidvdKVKSILTVEIMFFVMFL 168  Lachnoclostri...

WP_014434305  114 AWAWVRAHDPAADH----TEQPMDLMFMHSIRASLTYPPHDAWLAGYPIS-YYYFGYWLMNMVGLMAGQSAAVAYNLSQA 188  Caldilinea
4_pfamImport   68 AFVWVRLQNPDLWQpwfgGEKQMEFAFLNGILRSPTFPPVNPHFAGGVIN-YYYFGIYLVAYLTKLTGLYAEVAFNLAIP 146 
2_pfamImport   68 IGLTLRWFNPDLWHpargGEKPMDFAYLNAVLRSAAFPPLDPWHAGGYIN-YYYFGFVLVGALIHLSGVAPAVGYNLGVA 146 
WP_013559992 1056 FFLFVRLGNPDLWHpwkgGEKPMDFSYFNAVLKSVYFPPYDPWFAGGYIN-YYYYGFVLVGVPVKWLGIVPSVAYNLVLP 1134 Anaerolinea t...
WP_012874896  745 VGLLMRIANPDLWHpifgGEKPMELSFINAIQRSSNLPPYDPWFSGGYIN-YYYFGQWLAAVLMRLTFVGPAYGFNIAVA 823  Thermobaculum...
Q8TIR4         88 FFLIIRVHLPEIYM----HEKFMDSAFLNAVIRTSSFPPADPWFAGGSLDfYYYFGYLSVGVPGVLCAVKPSILFNLAVA 163  Methanosarcin...
WP_012874897  116 YLAILRAFVPEISQ----TEKPMDFMYLQTSYLSEVIPPRDIWFAGYGVN-YYYFGYYMVSILCRLSGISPAVGYNLGLA 190  Thermobaculum...
WP_015359094  149 FWTYLRGFNPKIEG----LEKFMDYGFVNSILRSGYVPPKDMWFAGKPIN-YYYFGQYVTAFLTRLSGLETEISYNVMMA 223  Thermoclostri...
CDE66574      133 LWTYLAGFHPEAHG----TEKFMDYGFMKAMMRSTAVPAEDLWYSGSGIN-YYYGGQFYAVFLTKITFTDVKQTYHLMRT 207 
WP_012200895  169 FWCYARGFKPEAYG----TEKMMDYGFMTSMMRTEYMPPVDTWFSGGSIN-YYYLGQYLGTYLSKLSGVGVEFGYNLMLM 243  Lachnoclostri...

WP_014434305  189 VWFGLLLSGAFGIGYNLVAAAGr----------------------------------------RFVAALGGGWVATLLVG 228  Caldilinea
4_pfamImport  147 TLFALTVVNVFAVAYSAVEKRIqestrareqesrrareeesrragehenshaltlsrshvplsHWWAGLGAALLAPLYVA 226 
2_pfamImport  147 TIFALTALGAFGVVYNLLAARSpq-------------------------------------pqRERTALIAAGLAPVLVL 189 
WP_013559992 1135 TLYGLLALGAFSFTWNALVKIYqkq------------------------------------etNRALPYVYSILGIVFLQ 1178 Anaerolinea t...
WP_012874896  824 WIFAVTGTLAFTFGYEISRRFF-----------------------------------------GGTFAQIVGFLSTLLMV 862  Thermobaculum...
Q8TIR4        164 LTFALSFNLFFGIGYNLTHGKI-----------------------------------------------RYGLLTAGFGM 196  Methanosarcin...
WP_012874897  191 TIFAVVAVITFSIVINLIRAAGl---------------------------------------rSIWIAVAGAIISLLLLL 231  Thermobaculum...
WP_015359094  224 TLFAFSMALCFTIVSNMLREHGi---------------------------------------eGECPAVAGGLIAAVLVS 264  Thermoclostri...
CDE66574      208 MVASFTFVLPFSITYHLAESRAchrirk------------------------------eggnkSQIAPVLGGLLSGGAVS 257 
WP_012200895  244 TLAGIAFTQCYSITYNVTRTFLqdstlrrrkta-------------------gehftlakskwKGLWCTLSGLISGFAVV 304  Lachnoclostri...

WP_014434305  229 LSSNLQGLLEWLHANGVDISWLAAWLQVRGFPenaevtr----------qwfisygWw----WWRSSRVLadvsl-rgdh 293  Caldilinea
4_pfamImport  227 VLGNLDGFAQVVRNLAKLNPSSNFQSAFGGLSdivaaiggl------qqvlegtaqWpp-ydFWGPSRVI---------- 289 
2_pfamImport  190 LIGNLAQAGWFLNGYAAEQMAKGRYE------------------------------Wa----FWDATRIT---------- 225 
WP_013559992 1179 VAGNLGALRMIWHGLMRLAAPDTQFLEAGILQkfiwtlqglgkylagaslpyprgdW-----YWIPSRAFps------nt 1247 Anaerolinea t...
WP_012874896  863 IVGNLDGLVQLMQSFASGNLSN----------------------------------FlgnfdFWRSTRITg--------- 899  Thermobaculum...
Q8TIR4        197 LLGNLQGLFEFVSMYVLKEQVSSMYY------------------------------W-------SSSRVI---------- 229  Methanosarcin...
WP_012874897  232 FAGNPVASILAWVNFNTPGSFD----------------------------------W-----FWKSTRVIfdfipgrngp 272  Thermobaculum...
WP_015359094  265 IGGNLHSFFYGFLAKFTKEGDKY---------------------------------W-----FPDATRYIgynp---ptd 303  Thermoclostri...
CDE66574      258 LAGNMHYVIYGCIRQWLGLNESAY--------------------------------W-----FPSSTRYIgydp--lven 298 
WP_012200895  305 FAANMHYPIYKHIKPWLEKISGKEVSSY----------------------------W-----FPNSTRYIgydp--vvet 349  Lachnoclostri...

WP_014434305  294 IEVIDEFPAFSYILGDNHPHVAAMPFAMLAVAAALVIFLQNSSSNFSSESRakfnfap-lfplgwgGFLLVAVITGSLLF 372  Caldilinea
4_pfamImport  290 DATINEFPFWSFLFADLHPHLIGIPLSGMFLAFALALLKRGTTDWRRSWRDgl------------aFVALFALLLGTLAS 357 
2_pfamImport  226 PGTINEFPFFTFLFADLHAHMIVMPLSLAALGLALAWMRKGTAAHWW-------------------IIGLLGLVAGAIRA 286 
WP_013559992 1248 GDPITEFPAFTFLYADLHAHLIALPITLLALCWALSVLLRDWDWDASQFFRqfld--------fgfTFIVGGLIIGALRP 1319 Anaerolinea t...
WP_012874896  900 GNIIHEFPFFTFLYADLHAHMVAMPMALGLLILAAYYVFISARKSRL-------------------IVIILASMLGSVLI 960  Thermobaculum...
Q8TIR4        230 PFTINEFPYFTFIHGDLHSHMLAIPFQLLVLGFLLNIYFRKNEHSIFENSL---------------SFFTFSIALGFLFP 294  Methanosarcin...
WP_012874897  273 QQTIDEFPAFTFLLGDLHPHLMAMPLLLGVLYCSVSNLYRQNKSTFLVL-----------------PVLLPGILIGALYM 335  Thermobaculum...
WP_015359094  304 DKTIHEFPVYSFVVSDLHAHVINMIFVLTLIGVLLAVFGKLQRKTLGNQDDkyrln-----eiffpEILLISLFICIFQM 378  Thermoclostri...
CDE66574      299 DRTIHEFPSYSFVLGDLHAHVVNVMFVLLVLGLLYSYVKNTCRDPEKEWKWslkdv------llqpQIIAAGFLIGVFHW 372 
WP_012200895  350 DQTIHEFPSYSFILGDLHAHVINIIFVLAVLGLLFAWLLYRKKKMDDIRYGitiqkpdflqeafhpIILLLGFFIGLFHM 429  Lachnoclostri...

WP_014434305  373 -LNTWDYPPYWLLTTFSIAVGVVGGVVRVKnflplqflpllppllqtTIAGLALFVAALLLYLPYLLTAQS-QVGGLIPN 450  Caldilinea
4_pfamImport  358 -VNLWELPTYFGLGVLTFLVSQFRSKGRIDwp-------------vtLLAALLYASGAYLLFAPFFLNYVNvGASGVGLV 423 
2_pfamImport  287 -TNTWDYPTFVGLAGLMVALATGRRWRqagrgwp-------atllvaLVVGAAPALVGNILFAPFIASFAT-ESSGIALW 357 
WP_013559992 1320 -TNTWDFPTYLALGSLALIYSIFRNgnvewfktkm--paemkkgimaLLAVGLLFLFSLVLYTPFAKWYGQ-GYSEIIPY 1395 Anaerolinea t...
WP_012874896  961 mTNPWDFPTYSGLFLLAVSIRALTScttllt-----------kllrvAHDSLTFIILSVAFCVPFFVHFKS-FYSSFGLV 1028 Thermobaculum...
Q8TIR4        295 -SNSWDFPVYFGLTLFVIFAFYYGHYIQKKntsys--------isgfFSTFILVSVFSFLPYLPFYLSFSPqAAEGFDFV 365  Methanosarcin...
WP_012874897  336 -TNSWDVPVAVLVFLLSIVTIGMYTQVLLRs----------------ALSIILLAFTSLVTSYPFVRHFDP-PVSSQSFI 397  Thermobaculum...
WP_015359094  379 -SNYWDFPIYLTVTLFVFICagirnygf-----------rkkttvvtVLRFVAVLLLSLLFALPFNLSFEK-IASTVRLA 445  Thermoclostri...
CDE66574      373 -SNYWDFVIYFVVIAGFSLYsalyryhar----------aketigtvLLQAAEAFAIGTIVALPFTMKFET-MVSGVGIA 440 
WP_012200895  430 -TNFWDFPIYFVVAGAVILFsnlviyqf-----------srvaviltAAQAVIIMLISSVVCKPFTESFNQ-ISTSIYLT 496  Lachnoclostri...

WP_014434305  451 Lf--------------------HPTRFSQYVAMFATALLTLTALLTFG-------------------------------- 478  Caldilinea
4_pfamImport  424 K---------------------APDPLDRWLLIWGFFLFVLISWTFYLagkrpkcpvskpsgvera-------------- 468 
2_pfamImport  358 Qgpgftll--------etiltaERTTTGQIVQIGGHWLIIWFVFVGLWawr----------------------------- 400 
WP_013559992 1396 Qg--------------------LRTPSWSYLTHWGLFLFLIVSWMGWEsidwmas------------------------- 1430 Anaerolinea t...
WP_012874896 1029 H---------------------ESVPVTLILIQLGLFFAIVLSYALVTllrd---------------------------- 1059 Thermobaculum...
Q8TIR4        366 Lp-------------------eSRTTIDKFLILFGLFLFLAFSFLVIRlds----------------------------- 397  Methanosarcin...
WP_012874897  398 PpqievipvinfighyigvvwwDHTDLLELLKVWGWHIAFSLFVLVCF-------------------------------- 445  Thermobaculum...
WP_015359094  446 R---------------------NHSLPHQLLVLWGYQLTFVIVFFIAIlyaeqntawkrlrgterlk------------- 491  Thermoclostri...
CDE66574      441 K---------------------HHSMLYQLAILWGLPTVLVVLFIAAVllawrknchlpgmerqgqivlad------gkt 493 
WP_012200895  497 E---------------------ARSMVHQMIVLWGLPFVICGYFVITRyydlkkegfitekkasykklrleqkevkrany 555  Lachnoclostri...

WP_014434305  479 --------------------WSVFRPRLKVVMICLALTLG-TPALLLTFiawvatgteegraslgnvalpdgassyLPFi 537  Caldilinea
4_pfamImport  469 --vglflrqfdflpralflhNRLVRAPGFFYLLFLALIPGcLALAIVAW---------------------------LAGw 519 
2_pfamImport  401 --------------------------qreSLLIVIVPLAV-WLVALGLN---------------------------LPA- 425 
WP_013559992 1431 --------------tpvsalNKLKPYRDLIYAGMVVFIGA-VFTLLLMK---------------------------VHI- 1467 Anaerolinea t...
WP_012874896 1060 ---------------------------thlrFILLVALGA-VIVGLSLN---------------------------RLS- 1083 Thermobaculum...
Q8TIR4        398 ---------------------------grkIGFFILLIGGsILLSMAWA---------------------------IPL- 422  Methanosarcin...
WP_012874897  446 --------------------TNLFHREDLRILVPLLLVSF-IGVIFGVH------------------------------- 473  Thermobaculum...
WP_015359094      --------------------------------------------------------------------------------      Thermoclostri...
CDE66574      494 qeeveeqavalilgekkpepGEKETAEKPKKVSAFCNFWReIA------------------------------------- 536 
WP_012200895  556 nnfdgnrlqklmmsyettvtYGGEKNKLYQWIESLQ-------------------------------------------- 591  Lachnoclostri...

WP_014434305  538 verwtaqpftFLIVGAMTAVALALLWTGiqhmvgaknflpqhfspqqgaldstpgvaapTPLLFVLALAVIGLGLTFTPE 617  Caldilinea
4_pfamImport  520 g--------vLALCLSWLGLAIAVLWRSaat--------------------------tdAGAALAAMLTATGLAILAGTQ 565 
2_pfamImport  426 ----------ILPLIGVLVTTAWLLWRIrr---------------------------rsFTIIVPLLWAFGGIGLWAMVE 468 
WP_013559992 1468 ----------AWLALPLATWAGVLLLRPds----------------------------sRVKKAIFFMIGTAMVLTLFVE 1509 Anaerolinea t...
WP_012874896 1084 ----------LGLLLALLICSISCLWQSrn----------------------------kQPLAIWLGLTSAGLAIWVLIE 1125 Thermobaculum...
Q8TIR4        423 ----------LAVLLPLLTLSLFIFLKDlp---------------------------erSATGFVSLLIATAAFLGLLCE 465  Methanosarcin...
WP_012874897  474 ----------ATLLLPLVVATLIIGFRTs-----------------------------sIGFRYACFLSVVGWLLVVLPE 514  Thermobaculum...
WP_015359094  492 ----------------------------------------arneltftvriknvlekfsTGDVFAVILCVSAMGLVLIPE 531  Thermoclostri...
CDE66574      537 -----------------------------------------------------------VSDMVIGILGLCAIGLIIIPE 557 
WP_012200895  592 -----------------------------------------------------------VADLFIVIMALCAMGLILLPE 612  Lachnoclostri...

WP_014434305  618 VVYLRDNF----GWRMNTIFKFYYQAWLLF 643  Caldilinea
4_pfamImport  566 VFYLKDFLngsdYYRMNTLFKFFSQTWVLW 595 
2_pfamImport  469 MVVVRGDV-----GRMNTVFKFGLHTWILL 493 
WP_013559992 1510 LFTLRGDI-----NRMNTVFKFYLQAWTLL 1534 Anaerolinea thermophila
WP_012874896 1126 IFYLRDFLdgstAYRMNTIFKFGVQSWILL 1155 Thermobaculum terrenum
Q8TIR4        466 VVFLDDPIsg-eFARMNTVFKFYIHLWIFL 494  Methanosarcina acetivorans
WP_012874897  515 FFYIRDVF----EDRMNTVFKFYYQSWQiq 540  Thermobaculum terrenum
WP_015359094  532 IVYVKDIYen-gYARANTMFKLTYQAFIMF 560  Thermoclostridium stercorarium
CDE66574      558 LVYVRDIYee-sYARSNTMFKLTYQAFILF 586 
WP_012200895  613 IIYVKDIYp--nHKRANTMFKLTYQGFIMF 640  Lachnoclostridium phytofermentans