WP_014434305    47 LTGYCFWIAYSLGLLRNDIGGAWLALIG-----VAIISVVAGRRKPGALAFsa--------lpSLRYILLFELLFLGAFA 113  Caldilinea
4_pfamImport     1 LAGWLLWMLTSLGLLRNTVLFSWLSVAF-----LAVVGAWIAYRQRKAMSAfi--------rtSWPLMLVGELLFAVAFL 67  
jgi:Caur_1339  794 LVAYLAWLGGSLHLVPFAPTTLWTIGMV-----VLGVGGFIGWRERTTLRRiw--------heRWSALAMAEMVFLAFLL 860 
WP_013559992   990 LWSYFVWLGGS-YKIPVTRTTITGVLVL-----LIGVGMVLAWLQRKDILQdi--------reQGKHFLFVEGLFAIFFL 1055 Anaerolinea ...
WP_013684214    20 TIVYITWILSSLRVLKFDFSVI-LALFS-----LLALSLLTLKRVK-----------------FSRGIILQEVLFVSTFF 76   Archaeoglobu...
Q8TIR4          29 LVAYFSWIFSY--IWGFNRVTILISVLV-----LCLLSIGLYRKKRIFP--------------ERKILLVNELVFLTAFF 87   Methanosarci...
WP_012874897    48 FVSWSTWYGLYLGIWDKNKGLIISVAALffisvLVAIVFFRSSFNRSLLFQ------------GWKYYLSLELIFVLAFS 115  Thermobaculu...
WP_015359094    78 ISSFIFWLLSYAKLLDITPAHCWSVTVAa---gLAVYVVFFGWKKFYRNISgii------dkdTFFWVFTGEGLFLFSLS 148  Thermoclostr...
CDE66574        70 VSGFAVFALGSFGLVPFTAPVCLITVGV-----LILASWIFGCFKVRVHAP------------EIDFLMMEEVLFFAFFL 132 
WP_012200895    89 IAGWVLWYLSSLRLLKFTRENAIITLVIcflvnLLIIGLSYYLKNRRDEKKcplndwyqidvdKVKSILTVEIMFFVMFL 168  Lachnoclostr...

WP_014434305   114 AWAWVRAHDPAADH----TEQPMDLMFMHSIRASLTYPPHDAWLAGYPIS-YYYFGYWLMNMVGLMAGQSAAVAYNLSQA 188  Caldilinea
4_pfamImport    68 AFVWVRLQNPDLWQpwfgGEKQMEFAFLNGILRSPTFPPVNPHFAGGVIN-YYYFGIYLVAYLTKLTGLYAEVAFNLAIP 146 
jgi:Caur_1339  861 IGLTLRWFNPDLWHpargGEKPMDFAYLNAVLRSAAFPPLDPWHAGGYIN-YYYFGFVLVGALIHLSGVAPAVGYNLGVA 939 
WP_013559992  1056 FFLFVRLGNPDLWHpwkgGEKPMDFSYFNAVLKSVYFPPYDPWFAGGYIN-YYYYGFVLVGVPVKWLGIVPSVAYNLVLP 1134 Anaerolinea ...
WP_013684214    77 ISLTYLMHKPEIYFa--ySEDFMDFAFLKSILRSDYFPPQDPWFAGENLS--YYFGHLIAAILIKISGVEAEAGYNLAVA 152  Archaeoglobu...
Q8TIR4          88 FFLIIRVHLPEIYM----HEKFMDSAFLNAVIRTSSFPPADPWFAGGSLDfYYYFGYLSVGVPGVLCAVKPSILFNLAVA 163  Methanosarci...
WP_012874897   116 YLAILRAFVPEISQ----TEKPMDFMYLQTSYLSEVIPPRDIWFAGYGVN-YYYFGYYMVSILCRLSGISPAVGYNLGLA 190  Thermobaculu...
WP_015359094   149 FWTYLRGFNPKIEG----LEKFMDYGFVNSILRSGYVPPKDMWFAGKPIN-YYYFGQYVTAFLTRLSGLETEISYNVMMA 223  Thermoclostr...
CDE66574       133 LWTYLAGFHPEAHG----TEKFMDYGFMKAMMRSTAVPAEDLWYSGSGIN-YYYGGQFYAVFLTKITFTDVKQTYHLMRT 207 
WP_012200895   169 FWCYARGFKPEAYG----TEKMMDYGFMTSMMRTEYMPPVDTWFSGGSIN-YYYLGQYLGTYLSKLSGVGVEFGYNLMLM 243  Lachnoclostr...

WP_014434305   189 VWFGLLLSGAFGIGYNLVAAAGr----------------------------------------RFVAALGGGWVATLLVG 228  Caldilinea
4_pfamImport   147 TLFALTVVNVFAVAYSAVEKRIqestrareqesrrareeesrragehenshaltlsrshvplsHWWAGLGAALLAPLYVA 226 
jgi:Caur_1339  940 TIFALTALGAFGVVYNLLAARSpq-------------------------------------pqRERTALIAAGLAPVLVL 982 
WP_013559992  1135 TLYGLLALGAFSFTWNALVKIYqkq------------------------------------etNRALPYVYSILGIVFLQ 1178 Anaerolinea ...
WP_013684214   153 AFFSIAVQSAFGIGYNLSGRKL------------------------------------------------HGLATAVLTC 184  Archaeoglobu...
Q8TIR4         164 LTFALSFNLFFGIGYNLTHGKI-----------------------------------------------RYGLLTAGFGM 196  Methanosarci...
WP_012874897   191 TIFAVVAVITFSIVINLIRAAGl---------------------------------------rSIWIAVAGAIISLLLLL 231  Thermobaculu...
WP_015359094   224 TLFAFSMALCFTIVSNMLREHGi---------------------------------------eGECPAVAGGLIAAVLVS 264  Thermoclostr...
CDE66574       208 MVASFTFVLPFSITYHLAESRAchrirk------------------------------eggnkSQIAPVLGGLLSGGAVS 257 
WP_012200895   244 TLAGIAFTQCYSITYNVTRTFLqdstlrrrkta-------------------gehftlakskwKGLWCTLSGLISGFAVV 304  Lachnoclostr...

WP_014434305   229 LSSNLQGLLEWLHANGVDISWLAAWLQVRGFPenaevtr----------qwfisygWw----WWRSSRVLadvsl-rgdh 293  Caldilinea
4_pfamImport   227 VLGNLDGFAQVVRNLAKLNPSSNFQSAFGGLSdivaaiggl------qqvlegtaqWpp-ydFWGPSRVI---------- 289 
jgi:Caur_1339  983 LIGNLAQAGWFLNGYAAEQMAKGRYE------------------------------Wa----FWDATRIT---------- 1018
WP_013559992  1179 VAGNLGALRMIWHGLMRLAAPDTQFLEAGILQkfiwtlqglgkylagaslpyprgdW-----YWIPSRAFps------nt 1247 Anaerolinea ...
WP_013684214   185 FTGFVSGLFQLLAYVTGTGIFNYKPFNGGLTD------------------------WlllfdFSSATRII---------- 230  Archaeoglobu...
Q8TIR4         197 LLGNLQGLFEFVSMYVLKEQVSSMYY------------------------------W-------SSSRVI---------- 229  Methanosarci...
WP_012874897   232 FAGNPVASILAWVNFNTPGSFD----------------------------------W-----FWKSTRVIfdfipgrngp 272  Thermobaculu...
WP_015359094   265 IGGNLHSFFYGFLAKFTKEGDKY---------------------------------W-----FPDATRYIgynp---ptd 303  Thermoclostr...
CDE66574       258 LAGNMHYVIYGCIRQWLGLNESAY--------------------------------W-----FPSSTRYIgydp--lven 298 
WP_012200895   305 FAANMHYPIYKHIKPWLEKISGKEVSSY----------------------------W-----FPNSTRYIgydp--vvet 349  Lachnoclostr...

WP_014434305   294 IEVIDEFPAFSYILGDNHPHVAAMPFAMLAVAAALVIFLQNSSSNFSSESRakfnfap-lfplgwgGFLLVAVITGSLLF 372  Caldilinea
4_pfamImport   290 DATINEFPFWSFLFADLHPHLIGIPLSGMFLAFALALLKRGTTDWRRSWRDgl------------aFVALFALLLGTLAS 357 
jgi:Caur_1339 1019 PGTINEFPFFTFLFADLHAHMIVMPLSLAALGLALAWMRKGTAAHWW-------------------IIGLLGLVAGAIRA 1079
WP_013559992  1248 GDPITEFPAFTFLYADLHAHLIALPITLLALCWALSVLLRDWDWDASQFFRqfld--------fgfTFIVGGLIIGALRP 1319 Anaerolinea ...
WP_013684214   231 PHTINFYPFFTFLQGDMHAHFTSIPFQLAFTGICLAIYQRFNV-----------------------ISFASALAFALFFI 287  Archaeoglobu...
Q8TIR4         230 PFTINEFPYFTFIHGDLHSHMLAIPFQLLVLGFLLNIYFRKNEHSIFENSL---------------SFFTFSIALGFLFP 294  Methanosarci...
WP_012874897   273 QQTIDEFPAFTFLLGDLHPHLMAMPLLLGVLYCSVSNLYRQNKSTFLVL-----------------PVLLPGILIGALYM 335  Thermobaculu...
WP_015359094   304 DKTIHEFPVYSFVVSDLHAHVINMIFVLTLIGVLLAVFGKLQRKTLGNQDDkyrln-----eiffpEILLISLFICIFQM 378  Thermoclostr...
CDE66574       299 DRTIHEFPSYSFVLGDLHAHVVNVMFVLLVLGLLYSYVKNTCRDPEKEWKWslkdv------llqpQIIAAGFLIGVFHW 372 
WP_012200895   350 DQTIHEFPSYSFILGDLHAHVINIIFVLAVLGLLFAWLLYRKKKMDDIRYGitiqkpdflqeafhpIILLLGFFIGLFHM 429  Lachnoclostr...

WP_014434305   373 -LNTWDYPPYWLLTTFSIAVGVVGGVVRVKnflplqflpllppllqtTIAGLALFVAALLLYLPYLLTAQS-QVGGLIPN 450  Caldilinea
4_pfamImport   358 -VNLWELPTYFGLGVLTFLVSQFRSKGRIDwp-------------vtLLAALLYASGAYLLFAPFFLNYVNvGASGVGLV 423 
jgi:Caur_1339 1080 -TNTWDYPTFVGLAGLMVALATGRRWRqagrgwp-------atllvaLVVGAAPALVGNILFAPFIASFAT-ESSGIALW 1150
WP_013559992  1320 -TNTWDFPTYLALGSLALIYSIFRNgnvewfktkm--paemkkgimaLLAVGLLFLFSLVLYTPFAKWYGQ-GYSEIIPY 1395 Anaerolinea ...
WP_013684214   288 gINTWDFPAYLILLIATAYL---------------------------ATKNRMFLIPGVAITMAFL--YSL-LNGYIGFV 337  Archaeoglobu...
Q8TIR4         295 -SNSWDFPVYFGLTLFVIFAFYYGHYIQKKntsys--------isgfFSTFILVSVFSFLPYLPFYLSFSPqAAEGFDFV 365  Methanosarci...
WP_012874897   336 -TNSWDVPVAVLVFLLSIVTIGMYTQVLLRs----------------ALSIILLAFTSLVTSYPFVRHFDP-PVSSQSFI 397  Thermobaculu...
WP_015359094   379 -SNYWDFPIYLTVTLFVFICagirnygf-----------rkkttvvtVLRFVAVLLLSLLFALPFNLSFEK-IASTVRLA 445  Thermoclostr...
CDE66574       373 -SNYWDFVIYFVVIAGFSLYsalyryhar----------aketigtvLLQAAEAFAIGTIVALPFTMKFET-MVSGVGIA 440 
WP_012200895   430 -TNFWDFPIYFVVAGAVILFsnlviyqf-----------srvaviltAAQAVIIMLISSVVCKPFTESFNQ-ISTSIYLT 496  Lachnoclostr...

WP_014434305   451 Lf--------------------HPTRFSQYVAMFATALLTLTALLTFG-------------------------------- 478  Caldilinea
4_pfamImport   424 K---------------------APDPLDRWLLIWGFFLFVLISWTFYLagkrpkcpvskpsgvera-------------- 468 
jgi:Caur_1339 1151 Qgpgftll--------etiltaERTTTGQIVQIGGHWLIIWFVFVGLWawr----------------------------- 1193
WP_013559992  1396 Qg--------------------LRTPSWSYLTHWGLFLFLIVSWMGWEsidwmas------------------------- 1430 Anaerolinea ...
WP_013684214   338 D---------------------ERTNAVDFLQIFAVFTFITLAYLAGIkl------------------------------ 366  Archaeoglobu...
Q8TIR4         366 Lp-------------------eSRTTIDKFLILFGLFLFLAFSFLVIRlds----------------------------- 397  Methanosarci...
WP_012874897   398 PpqievipvinfighyigvvwwDHTDLLELLKVWGWHIAFSLFVLVCF-------------------------------- 445  Thermobaculu...
WP_015359094   446 R---------------------NHSLPHQLLVLWGYQLTFVIVFFIAIlyaeqntawkrlrgterlk------------- 491  Thermoclostr...
CDE66574       441 K---------------------HHSMLYQLAILWGLPTVLVVLFIAAVllawrknchlpgmerqgqivlad------gkt 493 
WP_012200895   497 E---------------------ARSMVHQMIVLWGLPFVICGYFVITRyydlkkegfitekkasykklrleqkevkrany 555  Lachnoclostr...

WP_014434305   479 --------------------WSVFRPRLKVVMICLALTLG-TPALLLTFiawvatgteegraslgnvalpdgassyLPFi 537  Caldilinea
4_pfamImport   469 --vglflrqfdflpralflhNRLVRAPGFFYLLFLALIPGcLALAIVAW---------------------------LAGw 519 
jgi:Caur_1339 1194 --------------------------qreSLLIVIVPLAV-WLVALGLN---------------------------LPA- 1218
WP_013559992  1431 --------------tpvsalNKLKPYRDLIYAGMVVFIGA-VFTLLLMK---------------------------VHI- 1467 Anaerolinea ...
WP_013684214   367 ------------------------------rMAVILLSITtIGFLLNFQ------------------------------- 385  Archaeoglobu...
Q8TIR4         398 ---------------------------grkIGFFILLIGGsILLSMAWA---------------------------IPL- 422  Methanosarci...
WP_012874897   446 --------------------TNLFHREDLRILVPLLLVSF-IGVIFGVH------------------------------- 473  Thermobaculu...
WP_015359094       --------------------------------------------------------------------------------      Thermoclostr...
CDE66574       494 qeeveeqavalilgekkpepGEKETAEKPKKVSAFCNFWReIA------------------------------------- 536 
WP_012200895   556 nnfdgnrlqklmmsyettvtYGGEKNKLYQWIESLQ-------------------------------------------- 591  Lachnoclostr...

WP_014434305   538 verwtaqpftFLIVGAMTAVALALLWTGiqhmvgaknflpqhfspqqgaldstpgvaapTPLLFVLALAVIGLGLTFTPE 617  Caldilinea
4_pfamImport   520 g--------vLALCLSWLGLAIAVLWRSaat--------------------------tdAGAALAAMLTATGLAILAGTQ 565 
jgi:Caur_1339 1219 ----------ILPLIGVLVTTAWLLWRIrr---------------------------rsFTIIVPLLWAFGGIGLWAMVE 1261
WP_013559992  1468 ----------AWLALPLATWAGVLLLRPds----------------------------sRVKKAIFFMIGTAMVLTLFVE 1509 Anaerolinea ...
WP_013684214   386 ----------LAFLLALIVLLLQNRK---------------------------------KEAEFPAILALTAMLLLIFCE 422  Archaeoglobu...
Q8TIR4         423 ----------LAVLLPLLTLSLFIFLKDlp---------------------------erSATGFVSLLIATAAFLGLLCE 465  Methanosarci...
WP_012874897   474 ----------ATLLLPLVVATLIIGFRTs-----------------------------sIGFRYACFLSVVGWLLVVLPE 514  Thermobaculu...
WP_015359094   492 ----------------------------------------arneltftvriknvlekfsTGDVFAVILCVSAMGLVLIPE 531  Thermoclostr...
CDE66574       537 -----------------------------------------------------------VSDMVIGILGLCAIGLIIIPE 557 
WP_012200895   592 -----------------------------------------------------------VADLFIVIMALCAMGLILLPE 612  Lachnoclostr...

WP_014434305   618 VVYLRDNF----GWRMNTIFKFYYQAWLLF 643  Caldilinea
4_pfamImport   566 VFYLKDFLngsdYYRMNTLFKFFSQTWVLW 595 
jgi:Caur_1339 1262 MVVVRGDV-----GRMNTVFKFGLHTWILL 1286
WP_013559992  1510 LFTLRGDI-----NRMNTVFKFYLQAWTLL 1534 Anaerolinea thermophila
WP_013684214   423 LFYIDDAYee-pYERMNTVMKVYMEVWLLW 451  Archaeoglobus veneficus
Q8TIR4         466 VVFLDDPIsg-eFARMNTVFKFYIHLWIFL 494  Methanosarcina acetivorans
WP_012874897   515 FFYIRDVF----EDRMNTVFKFYYQSWQiq 540  Thermobaculum terrenum
WP_015359094   532 IVYVKDIYen-gYARANTMFKLTYQAFIMF 560  Thermoclostridium stercorarium
CDE66574       558 LVYVRDIYee-sYARSNTMFKLTYQAFILF 586 
WP_012200895   613 IIYVKDIYp--nHKRANTMFKLTYQGFIMF 640  Lachnoclostridium phytofermentans