Conserved Protein Domain Family
DUF2142

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pfam09913: DUF2142 
Predicted membrane protein (DUF2142)
This domain, found in various hypothetical prokaryotic proteins, has no known function.
Statistics
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PSSM-Id: 401765
View PSSM: pfam09913
Aligned: 15 rows
Threshold Bit Score: 203.812
Threshold Setting Gi: 123751120
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q5Z3D8        116 LatlFGAVFAVITPPFWGHDEITQFGRAY-------QV-AH---GGF------LPTEIEDDRGVAYGGVIPPGiddlm-- 176 Nocardia farci...
Q01XM3         38 L---MALAFAVVMPPFQVPDEDGHFIRAY-------LI-SR---GEF------VGRGAPRVPGTVVLSMMRYPemgerf- 96  Candidatus Sol...
Q83H24         46 Fi--SLAGWALSSPIGSSPDDDFHLASAW------------------------CALGDRPGLCESSGIKDAKKvpttild 99  Tropheryma whi...
jgi:Acel_0442  16 Fg--ITALWAVTTPKYAAPDEPAHAVKAA-------ANvRGefrG--------TPQPADHIPYEAFTVPATL-------- 70  Acidothermus c...
Q2JAW9         81 Ll--LVAAWVATNPPGFGPDEPAHFVKAVgagtgqwTGtPGrlaHPSfgngpgRAERIDWINRNSRVFALPAGln----- 153 Frankia casuar...
Q0RGM1         18 L---LLAAWVGSNAPGFGPDEPANFVKEVgagtgqwSGtPGrlaHPAfgaqpgAPERIDWINRNSRVFRLPAGld----- 89  Frankia alni A...
WP_011527294   21 Ff--WGVIFLFLIPPFQAPDEQVHFPRVF-------EL-SC---GKI------LLSKGEKVGGSNLPTSIQAF------- 74  Lawsonia intra...
Q97N14         17 Lf--FGVLFAVINAPFQDPDEPIHFYRAY-------QI-ST---GQM------FEQKNNSGIGGYLPQNLIKTs------ 71  Clostridium ac...
Q9A0F5         71 Lv--FGTISAIISPINDIPDEYVHYSRTV-------YI-SE---GDIn-----LTNNNKKL------------------- 113 Streptococcus ...
bgi:05SSU1282  36 Ip--FLLISIFVMPVTKVPDEATHAFMSW-------NIlFD------------SPTSRDTEAMNELR------------- 81  Streptococcus ...
Q5Z3D8        177 -gyafHDYQENPEEPGAMVADPGAYERLRSADIGTELRPIWFTNTAA-YSPVAYVPAAVGIRVAEAVGLDVGGVVLLTRL 254 Nocardia farci...
Q01XM3         97 grfkpRELVRDLIPHPGSVSPEVPSLNLGNLDVRHRWLPWSIIGSSL-YCPLVYMPASLGIATVRILSGSPLLMMYGARL 175 Candidatus Sol...
Q83H24        100 twhgkGSRHGNLYCFLNGVSPECQNKWLGNTDHKMQDTGRVNFGNNAqYTNLYYSAMGL------LASDDVRASVWGMRL 173 Tropheryma whi...
jgi:Acel_0442  71 -----AQGNPACIAFQPEQSAACLPRWTAQSGLTEALTYVGG------YPPLYYLLVGL-----PTLVTNGKDVLFWMRL 134 Acidothermus c...
Q2JAW9        154 ----pGAAGLPCDLFRDWVSVACLDRPRPRPPATRALSYVGT------YEPYLYAVEGA----VMIHTHTADGALYAGRA 219 Frankia casuar...
Q0RGM1         90 ----pGRAGFPCNLFRNWLSVSCLDRPHSRPPATRALSYVGT------YEPYVYAVPGA----AMARTDTALGALYTGRA 155 Frankia alni A...
WP_011527294   75 -----TSIRGDIPFHKEHKFDYKTLYHHLTTPINERETTFITFSTQL-YSPFQYLPQVLGVRVGKIFNISICILYYLGRL 148 Lawsonia intra...
Q97N14         72 -----ENLSEDIKAKSNKKQDINKIKYYLNLPLNKNKVAFNDFRSATiYSDIVYIPQSIGINLAKIFRASALYMMYFGRI 146 Clostridium ac...
Q9A0F5        114 ------RISKDVDKLIKQSGKTFITSNLKATKHSTREYSYPYIKGTNaYYSFSYIPQALGILVGNALDLPILLTYYFGRL 187 Streptococcus ...
bgi:05SSU1282  82 ------AADFTYSEPEIHAVDSTEYSSLFTKIRDFSKDKLSIDFS---LKSLMSTPQLIGLVVGKLLYPSYGMMVTIGRL 152 Streptococcus ...
Q5Z3D8        255 AGLLGYLVVAGFALYALRAHRiqWL---AFTVAVLPIAIFQAGTVTADTMTNALALLVSALLVKg--lFLGRDLTRA--E 327 Nocardia farci...
Q01XM3        176 FNVIVFAAALAISFRLAPRYR--AL---FTAVALMPMTLQQAGGISADLVTIAFSFVGFSLVLH----SREHFVSRR--L 244 Candidatus Sol...
Q83H24        174 INAFIFTALSLLLYLALPQPRraALl-iTWSLSLVPAAMFFIPSSNPSSWAFIGVPSTFFAMLS----FFETRGRRKicL 248 Tropheryma whi...
jgi:Acel_0442 135 VSAALSSLFLAVGFVAASRIRraRWtvlGVAAAVTPMALFLASVVNPSGLEISAALATWTCALAa---FASREDPPPrgL 211 Acidothermus c...
Q2JAW9        220 TSAAIVVTLLTIIIFASWDSRagLLsvgGVLLAVSPMALFLGSVLGTNGMEIAGATALFTLALR----LGRPGAPPRw-I 294 Frankia casuar...
Q0RGM1        156 VTAALVAGLLAVAVAAAWSGPagPLsvaGVLLAASPMVLFMGSVLGTNGIEIAAATALFALVLR----MGRATGPPRw-A 230 Frankia alni A...
WP_011527294  149 FSLCIIGVLLYLSIKYMPFNK--WA---LVMLCLSPMSLFLAVSHSSDPMIFACSFLLIAIVLRsm-yDTSFRLSVS--I 220 Lawsonia intra...
Q97N14        147 ANLICWTIIVFFSVKLIPFKK--NL---MAFLALTPMNLYQAASLSADAMTNSMAFLSIALVLRyafgEEEAKLTKR--Q 219 Clostridium ac...
Q9A0F5        188 CNLISYAMLAFIAIKLSGSFK--QV---IAVVTLLPMNIYLAASFNQDGFAIGLVLVTIGLFINl---LSSKDKSNYntK 259 Streptococcus ...
bgi:05SSU1282 153 FNTIVYIIGIYYLIKKIKYGK--MT---LFFVSLLPMMIQQAGSLSYDVVNYLAVVAFFVFYVNl---LVDKVLTTR--K 222 Streptococcus ...
Q5Z3D8        328 TVALLAATLLLPLSKp---TYVLLAMLVVLIP-------VRRFAFFGgvaatgf------------------------dw 373 Nocardia farci...
Q01XM3        245 LILIVLVFVMWVLCK----SSIWALPLLLLIP-------VSAFKNRL--------------------------------- 280 Candidatus Sol...
Q83H24        249 GIIAVFSVLLSAFARsdaaIYALLAIVISGIL-------QVRDFKNP--------------------------------- 288 Tropheryma whi...
jgi:Acel_0442 212 VLWTAVSASVLVQVRglspLLLAVIGLTVVGVtgwqpvlRVLRRRDG--------------------------------- 258 Acidothermus c...
Q2JAW9        295 WPALGLVAALVALSRpsgpLWVLLTPMIAAGL-------AAPRARARavdavpaveqprpverprstegtqptegprrhr 367 Frankia casuar...
Q0RGM1        231 WPAVGVVGALLALSRptgpAWVLLAPLVGLVL-------AERRGAGRcrgadr--------------------------- 276 Frankia alni A...
WP_011527294  221 TGLLLLCIATLATSKf--gSYFPILLIVLLMP-------TIVFSDKR--------------------------------- 258 Lawsonia intra...
Q97N14        220 IVTMIIAFTLLAFSKr---IYFVMCILFFIIP-------IKKFNSKKd-------------------------------- 257 Clostridium ac...
Q9A0F5        260 FFLYLVLCGLLVLSKf---TYFLLVCLPLFIP-------NEKFGKNTkl------------------------------- 298 Streptococcus ...
bgi:05SSU1282 223 FINLILLSLLLYLTKa---NNILLLALLFFVD-------FEFEG------------------------------------ 256 Streptococcus ...
Q5Z3D8        374 rrlipWVFAGTGAVAFAIWMKIAAPTGDGMSLMRPRHQ---WYTVKPDEQLGEILGDPFRFLG--------VFRDSI--- 439 Nocardia farci...
Q01XM3        281 -----TWAAYLGVASVCMVGALLVWNNVTAPNLETFRAvrlTHGVDMPANIRLVGAHPLMFVR--------YLIGVV--- 344 Candidatus Sol...
Q83H24        289 -----WAQFALPVALGIMSIATFFMYPLNVAATGLPA------------TGARDYGFI-------------TFVKNIifi 338 Tropheryma whi...
jgi:Acel_0442 259 -----QIGAGILAASSIFALVWIFAMGSLKLAGAGQP----------------VAPNASNWQIf------tTAIRAV--- 308 Acidothermus c...
Q2JAW9        368 lvgwlSVPWIALAVAGVVATAVWERRVQPHPGIRREL---------AEQGLRQLSSDAPAWAR----------------- 421 Frankia casuar...
Q0RGM1        277 wrrawPVPWLGLAAGGVVATTLWERAVQPHPGIRRAL---------VVEGLHRLPHDADAWVR----------------- 330 Frankia alni A...
WP_011527294  259 ------VGYIFKLMLFAIGIALALFWNLKTKFIFDELS---DSNAIFTNNIHMLCSY--EYIQ--------LVLRTF--- 316 Lawsonia intra...
Q97N14        258 -----YIGTFVIMLGACLMSLVTVSVISKILAIKVSA------GSYTPGQMEFVLSHPITYIH--------ILLRTF--- 315 Clostridium ac...
Q9A0F5        299 ----vILKKLGGLLLIFLFAAMWFRLYGQVKTPYVADF---LKEVNVSQQVKNMLESPIVYSS--------IIIRHM--- 360 Streptococcus ...
bgi:05SSU1282 257 -----VLSKFNSILKWIQKRRLPILIL--------------------GFGLVLLVSYLFLHNRggvvhfvkVMINSLfin 311 Streptococcus ...
Q5Z3D8        440 --VYRDQRWFTQFfgELGFAYIDVPA-------LAVLGCLLALAVSLGIGDRMdaaaatTRRTLLVALTVAASVAMIYVT 510 Nocardia farci...
Q01XM3        345 --GSNLKPEIGQF--IGAFGWLRFPLpsw-vraAYLLLVLVTAVTEFPAKSFR------TWERGVLALVLLGGVLFVHAA 413 Candidatus Sol...
Q83H24        339 psSFLPSVFTPQF-----LGWLDVPLyppayvfVAIAALIIVGFA-LGVGGVR---------KLFAVLLTLAALIIAPLY 403 Tropheryma whi...
jgi:Acel_0442 309 --GLNMYQLFGVF------GWLDTNMptw-cyfAWEAICALLALAVLVRREFR---------LAVVIAGVVAVTILLPTA 370 Acidothermus c...
Q2JAW9        422 -------QWVGVF------GWASLRMpsf-aywTWGACLLVLLGAAFVVGTWR---------QRIRLGAVLIGVVAVAVV 478 Frankia casuar...
Q0RGM1        331 -------QWVGVF------GWASLPMpty-ayrIWWVAVVALALVALAAGPWR---------ARLGFVAVLVGAAVVAVG 387 Frankia alni A...
WP_011527294  317 --IILAHRLYLSF---FTLGWLDTPLpni-mcyCWGVLLILLTVFSSSSISAYi----pLLTRILFFFISLVISIGIVTS 386 Lawsonia intra...
Q97N14        316 --HFKMSFYAISF--IGVFGWLDTRLpln-lylFYGVALVLIALFEHTLIEKN-------KDRIIMFIVFIINVGLIMSA 383 Clostridium ac...
Q9A0F5        361 --VINLINMNNIF----QFGALSYGItnl--fpLYVCFFFFVYISNASKITIN------IVEKMGIIFVISAIIGATVLA 426 Streptococcus ...
bgi:05SSU1282 312 nrNDHLNGILTVGi-FGYFGWFVTQLplw-lifIDIFIFTLLLFNDGNLKISK-------TEGLASLFVLPVQVAIIVAG 382 Streptococcus ...
Q5Z3D8        511 LYMSFTPVGFYI----IDG--------VQGRYfvp-lalT 537 Nocardia farcinica
Q01XM3        414 MCISDTTLCSGT----LNSgcrdesivFQGRY-------L 442 Candidatus Solibacter usitatus Ellin6076
Q83H24        404 VSQVAGITADKL---------------LQPRYlap-laiI 427 Tropheryma whipplei str. Twist
jgi:Acel_0442 371 LASLEARKLGIV---------------GQGRYilpvavgA 395 Acidothermus cellulolyticus 11B
Q2JAW9        479 LDVLVLRQTRFP---------------VYGRYllpiavlV 503 Frankia casuarinae
Q0RGM1        388 LDVVVLRQTRFP---------------VYGRYllplavlL 412 Frankia alni ACN14a
WP_011527294  387 MYLGCGTTGENV----ING--------IQGRYffpismlV 414 Lawsonia intracellularis
Q97N14        384 LYVSWTPKAANI----IEG--------IQGRYfipiiplL 411 Clostridium acetobutylicum
Q9A0F5        427 MYLTWTPVGSST----VLG--------VQSRYligiiplV 454 Streptococcus pyogenes serotype M1
bgi:05SSU1282 383 MYFAWTPTAIGPnamiSQG--------AQGRYftpflvyL 414 Streptococcus suis 05ZYH33
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