8IUE


Conserved Protein Domain Family
SNAPC1
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pfam09808: SNAPC1 (This model is not part of the current CDD release)
Small nuclear RNA activating complex (SNAPc), subunit 1
Members of this family are part of the SNAPc complex (SNAPC1) required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. They bind to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Furthermore, they also recruit TBP and BRF2 to the U6 snRNA TATA box.
Links
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Statistics
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PSSM-Id: 519077
Aligned: 60 rows
Threshold Bit Score: 119.251
Created: 15-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
8IUE_1         7 LQTDCEALLSRFQETDSVRFEDFTELWRNMKFGTIFCGRMRNlEKNMFTKEALALAWRYFLp-PYTFQIRVGALYLLYGL 85  human
XP_009103854  32 FKRDIDELIDEFVESDLTTFGDMKRVWLSRKFSYIYEAFPNT-NLAFFIQSLYAHTIGHMVs-IDSFSRRLGGLYCLYCL 109
Q8LNT0         6 FKLDIDELLADYTEANCTAFADFKRLWMAKKFSYIYEGRPKT-NSGAFMQSLFLHCIGHMTs-QSCMPQRLAGLYCLYCL 83  Japanese rice
XP_010237075   6 FKLDISELIADYAKENYTAFTDFKRVWTAKKFSYIYEGRPKT-NSGVFMQSLFLHCIGHMTs-QSSLSQKLAGLYCLYCL 83 
XP_002285409   6 FKLDIDELINEFTESKSMTLDDMKRVWLSRKFSYIYEARPSS-NLAFFMQSLYSHSISYMSd-TASLSHRLGGLYCLYCL 83 
XP_006836204   6 FKRDVDDLLGEFIEIGAVTLAEMKKVWVSRKFTYIYEAMPSShNLAFFMQALYAHAIGYMVt-EGSLSKRLGGLYCLYCL 84 
XP_002531959   6 FKQDIDELIDEFVQGESPTFAEMKKVWLSRKFSYIFEAMPCN-KLALFMQSVYSHSIGYMInsSASLSQRLGGLYCLYCL 84 
XP_024458923   6 FKLDIDELINEFVEGEFTTLADMKRVWLSRKFTYIFEASPPT-KLAFFMQSLYAHTIGHMIs-TSSLSQRLGGLYCLYCL 83 
XP_004242759   6 FKLDIDELINEFAKGGSPTFAEMKRVWVSKKFSYIFEASPPK-DQACFIQSLYAYCIGYMVs-TNSLLSRLGGLYCLYCL 83 
XP_040864093   6 FKQDIDELIGEFTQDESTTLAEIKRVWLSRKFSYIYEARPSA-NLAFFMQSLYAHCIGYMVg-TATLSHRLGGLYCLYCL 83  soybean

8IUE_1        86 YNTQLCqpKQKIRVALKDWDEVLKFQQDLVNAQHFDAAYIFRKLRLDRAFHFTAM-----PKLLSYRMKKKI-HRAE--V 157 human
XP_009103854 110 HDIQPFkpKFRIYISLQELGKFRDLIVEAKEKGVEIATAVGKQMLDKNVFIFGAVdfdetSTTEKLHQSIELqNRLVrcA 189
Q8LNT0        84 YESQPYkpHFKIYLSLEELKKLKDFVVEAKQNGMAVVPSLVKRMLDKGMILFGFInllgdSGVKQVNELTASqNKRVkfA 163 Japanese rice
XP_010237075  84 YECQPYkpHFKIYLSLEESKKLKDFVVEAKQNGVGFVPALVKRMLDKGMFLFGFVnllgvHGAKQVDELNESqNKRVkyA 163
XP_002285409  84 YETQPCkpPFKIYLSLGDLKKLKDLAANAKEKGVEVAPALIKRMLDRKIFLFGFVdinesSVRERVNDLADLqNARIqvA 163
XP_006836204  85 YETQPFvpPFKIYLSLVELQKLKILVADAKRNGIEIALAVVKRMLSKNMFLFGHVnanedSVTAVISGITKQqNTQIraA 164
XP_002531959  85 YETQPFkpPFKIYLSLGELKKLKNLVVDAKEQGVQVVPVIVSRMLEKDMFLFGSVdlnegSTTELVDQLTQLqNDRVqhA 164
XP_024458923  84 YETQPFkpPFKIYFSLGELKKLKNLVINAKEHGIKVVPALVKRMLEKNMFLFGFVdlhegSVSETVNQLTELqDARVqvA 163
XP_004242759  84 YETQPFkpPFKIYLSMGELKNLRNVVAEAKAKDVKVVPAVVKRMFDRNMFLFGFVdvnesSAAERLDELSEVqNASIqiA 163
XP_040864093  84 YETQPFnpSFKVYLSLGELKKLRILVADAKANDIKVALALVKRMLERNTFLFGSVdlmegCVTETVNELQQLqNARIqvA 163 soybean

8IUE_1       158 TEEFKDPSDR---VMKlit-sdvLEEMLNVHDHYQNMK 191 human
XP_009103854 190 YKKLTSETEIdkfIHLdmgkevdLSSIHKQSIEYAEAK 227
Q8LNT0       164 CDKLFMNTQIdsyMHMdlgseleLDKIKKSSLDYAKAK 201 Japanese rice
XP_010237075 164 CDKLFANTQIesyMRTdlgeefeVDNIKKLSMDYAKAK 201
XP_002285409 164 YNKLLANSRIehfLHMdmgmefdLKGLNKISTEYANAR 201
XP_006836204 165 HDMLLSNSKIeehVNMdlsskldLEGLKNLSADYAKTK 202
XP_002531959 165 YKKLFPDTRLkqfLHMdldsefdFNAVTKMSTEYAEAK 202
XP_024458923 164 YKKLFDDTRIeqfLHMdmgmefdLEMLKKMSTEYAEAK 201
XP_004242759 164 CKKLFANSRIehfTHMdmgleleVDMLKQKSADYARAK 201
XP_040864093 164 YEKLFDSTSIdnyIQMdlglevdLDLLKKKSSGYATAK 201 soybean
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