Conserved Protein Domain Family
SNAPc_SNAP43

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pfam09808: SNAPc_SNAP43 
Small nuclear RNA activating complex (SNAPc), subunit SNAP43
Members of this family are part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. They bind to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Furthermore, they also recruit TBP and BRF2 to the U6 snRNA TATA box.
Statistics
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PSSM-Id: 401677
View PSSM: pfam09808
Aligned: 65 rows
Threshold Bit Score: 121.17
Threshold Setting Gi: 124451439
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_001994197       5 VYGDCWKLLQRFSSavaataGQDAKFELFCEMWHTLRMQHIYSAQTNHiEVIETTMAALHVAKRVAC-GRrtngdafaaT 83  Drosophila ...
XP_006381113       6 FKLDIDELINEFVE------GEFTTLADMKRVWLSRKFTYIFEASPPT-KLAFFMQSLYAHTIGHMIsTS---------S 69  black cotto...
XP_003542638       6 FKQDIDELIGEFTQ------DESTTLAEIKRVWLSRKFSYIYEARPSA-NLAFFMQSLYAHCIGYMVgTA---------T 69  soybean
CBI28242           6 FKLDIDELINEFTE------SKSMTLDDMKRVWLSRKFSYIYEARPSS-NLAFFMQSLYSHSISYMSdTA---------S 69  wine grape
XP_009397732      13 FKLDIDELVDEFNE------GNHTTLADMKKMWMAKKFSYIYEAKPIS-NEAIFMQSLYSYSISHMVsTG---------A 76  wild Malays...
XP_004963061       6 FKLDIDELVADYGK------ENSTTLADFKRVWKEKKFSYIYEGRPNA-NSCLFMQSLFLHCIGHLTsES---------S 69  foxtail millet
XP_014757447       6 FKLDISELIADYAK------ENYTAFTDFKRVWTAKKFSYIYEGRPKT-NSGVFMQSLFLHCIGHMTsQS---------S 69  stiff brome
XP_010323288       6 FKLDIDELINEFAK------GGSPTFAEMKRVWVSKKFSYIFEASPPK-DQACFIQSLYAYCIGYMVsTN---------S 69  tomato
JCVI:AT3G53270.6   6 FKRDIDELIDEFVE------DDLTTFADMKSVWLSRKFSHIYEASPNS-NLAFFMQSLYVHTIGHMVsID---------S 69  thale cress
XP_009103854      32 FKRDIDELIDEFVE------SDLTTFGDMKRVWLSRKFSYIYEAFPNT-NLAFFIQSLYAHTIGHMVsID---------S 95  field mustard
XP_001994197      84 RAERIGAIYLLYAIYNKQPTMRFIKIEVSPSTWQCLtgyvEQLRRVEAERRDTqQVSYVFWRLVQDQAFRYTALDYCQAL 163 Drosophila ...
XP_006381113      70 LSQRLGGLYCLYCLYETQPFKPPFKIYFSLGELKKL----KNLVINAKEHGIK-VVPALVKRMLEKNMFLFGFVDLHEGS 144 black cotto...
XP_003542638      70 LSHRLGGLYCLYCLYETQPFNPSFKVYLSLGELKKL----RILVADAKANDIK-VALALVKRMLERNTFLFGSVDLMEGC 144 soybean
CBI28242          70 LSHRLGGLYCLYCLYETQPCKPPFKIYLSLGDLKKL----KDLAANAKEKGVE-VAPALIKRMLDRKIFLFGFVDINESS 144 wine grape
XP_009397732      77 LSTRLGGFYCLYCLYETQPYKPAFKIYLSLCELKRL----KILVIDAKKIGIA-IVPALVKKMLDKNMFIFGFVDRVDGY 151 wild Malays...
XP_004963061      70 LPRRLAGLYCLYCLYECQPYKPQFKIYLSLEECRQL----KDFISMAKQNGVH-LVPALVKRMLDKGMFLFGYMNLLGDN 144 foxtail millet
XP_014757447      70 LSQKLAGLYCLYCLYECQPYKPHFKIYLSLEESKKL----KDFVVEAKQNGVG-FVPALVKRMLDKGMFLFGFVNLLGVH 144 stiff brome
XP_010323288      70 LLSRLGGLYCLYCLYETQPFKPPFKIYLSMGELKNL----RNVVAEAKAKDVK-VVPAVVKRMFDRNMFLFGFVDVNESS 144 tomato
JCVI:AT3G53270.6  70 FSRRLGGLYCLYCLHEIQPFKPKFRIYISLQELGKF----RDLVVEAKDKGVE-IAAAVAKKMLDENMLIFGAV--DETS 142 thale cress
XP_009103854      96 FSRRLGGLYCLYCLHDIQPFKPKFRIYISLQELGKF----RDLIVEAKEKGVE-IATAVGKQMLDKNVFIFGAVDFDETS 170 field mustard
XP_001994197     164 DALAAYDSLESFAESKk-TKNKTAllkhQltqseanIRE------ELHSLAQLAHAAQSAC 217 Drosophila grimshawi
XP_006381113     145 VSETVNQLTELQDARVqvAYKKLF----DdtrieqfLHMdmgmefDLEMLKKMSTEYAEAK 201 black cottonwood
XP_003542638     145 VTETVNELQQLQNARIqvAYEKLF----DstsidnyIQMdlglevDLDLLKKKSSGYATAK 201 soybean
CBI28242         145 VRERVNDLADLQNARIqvAYNKLL----AnsriehfLHMdmgmefDLKGLNKISTEYANAr 201 wine grape
XP_009397732     152 ESQRVDEIMKLENKRIqiAYEKLL----GntliedyLHMdlgmelELSTLKKMSKEYAEAK 208 wild Malaysian banana
XP_004963061     145 GEKQVEELTAMQNKRIkfACDKLF----AntqaesyMHLdlgaefELDSIKKLSKEYAEAK 201 foxtail millet
XP_014757447     145 GAKQVDELNESQNKRVkyACDKLF----AntqiesyMRTdlgeefEVDNIKKLSMDYAKAK 201 stiff brome
XP_010323288     145 AAERLDELSEVQNASIqiACKKLF----AnsriehfTHMdmglelEVDMLKQKSADYARAK 201 tomato
JCVI:AT3G53270.6 143 ATKTIHQLTELQNARVrfAYEKLI----CdtsinqfIHLdmgkevDLNSLDKMSIEYAEAK 199 thale cress
XP_009103854     171 TTEKLHQSIELQNRLVrcAYKKLT----SeteidkfIHLdmgkevDLSSIHKQSIEYAEAK 227 field mustard
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