3JCR


Conserved Protein Domain Family
Prp31_C

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pfam09785: Prp31_C 
Prp31 C terminal domain
This is the C terminal domain of the pre-mRNA processing factor Prp31. Prp31 is required for U4/U6.U5 tri-snRNP formation. In humans this protein has been linked to autosomal dominant retinitis pigmentosa.
Statistics
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PSSM-Id: 401657
View PSSM: pfam09785
Aligned: 89 rows
Threshold Bit Score: 87.6205
Threshold Setting Gi: 284096922
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3JCR_J       337 VKQVKPLPAPLDGQRKKRGGRRYRKMKERLGLTEIRKQANRMSFG-EIEEDAYQEDLgFSLGHLGKS--G--SGRVRQ-T 410
EDQ92511     345 VKNVKALPKPDEAPRKKRGGKRFRKMRDKYAMTRARKAANRMGFGeLEEDEFQD--EaQVNKVLKEK------GSVRV-T 415 Monosiga brevic...
EGD74347     350 gKTVKALPRPDDPYKKRRGGKRFRRQKERQATTEAMKAANRMTFG-EIEEDVVQEEMaAFSGPRVAK------GRLRA-V 421 Salpingoeca ros...
PDM66803     339 VKNNKALPKPLDKASKKRGGRRVRKMKERLGMTDMRKKANRMNFG-ELEEDIMQERLgYGVGQLKQGgpS--TGRIRM-G 414 Pristionchus pa...
EGT47772     347 VKANKALPKPLDKASKKRGGRRMRKMKERLGMTDLRKSANRMNFG-ELAEDVMQEHMgFDIGQVKTG--NvtGGRIRA-A 422 Caenorhabditis ...
EJW82755     333 VKAAKPLPKPLDKASKKRGGRRVRKMKERLGMTELRKKSNRMNFG-ELAEDVIQENMgFSLGQALSG--PssGSRIRS-A 408 Wuchereria banc...
XP_002109132 337 LKKIKPLIVPGEYRKKKRGGRRVRKLKEKAAVTELRKQANRMTFG-QIEEDAYQGDLgFSLGQLGQ---St-SGKVRG-A 410 Trichoplax adha...
XP_003382952 332 VKRIKPLPKPDDMPKKRRGGKRIRRLKQKVILTDIRKQANRMSFA-EIEDDAYQEDLgFSVGQLGKG--Gv-GGPIRGpA 407 Amphimedon quee...
CDS43033     402 VKQVKALPAPIDPPAKKRGGRRYRKMKERLGMTEMRRSANRIQFG-QVSEDAYQSDLgFSLGSLGQR--Gv-AGHLRV-P 476 Echinococcus mu...
XP_004342635 417 prLPKPLPAPKEGRKNKRGGARVRKAKERVAPTELRKQANRVSFGvAAEHQNQM-DLgYDLGIAGNA--S--NGKIRV-A 490 Capsaspora owcz...
3JCR_J       411 QVNEATKARISKTLQRTLQKQS---VVY-------------------------GgkstirdrsSGTaSSVAFTPLQGLEI 462
EDQ92511     416 EQKQKG-GAISKRMQKRLQQESglmTTLrn---------------------ssV---------AGT-ASVSFTPLQGLEI 463 Monosiga brevic...
EGD74347     422 EATQKG-GALSKKMQRRLQREAshgGMStir-------------------gtaT---------AGT-ASVSFTPMQGLEI 471 Salpingoeca ros...
PDM66803     415 VVDEKTRVKMSKTLQRTMEKQK---GIGggts-----------------irskV---------SGTaSSVSFTPVQGLEI 465 Pristionchus pa...
EGT47772     423 AVDQKTRARMSQKMMRQLERQK---ANggmts-----------------irskV---------AGTaSSVTFTPIQGLEI 473 Caenorhabditis ...
EJW82755     409 TVDPKTRARMSQKLQKTMERQR---SMggvts-----------------vrsrA---------AGTaSSVTFTPVLGLEI 459 Wuchereria banc...
XP_002109132 411 PVDKKTQVSVSKKLQKTLQQDN---QTyggrs----------------svrgaT---------SGTaSSVAFTPLQGLEI 462 Trichoplax adha...
XP_003382952 408 AVDKKTQISISKRLQRQIQK-S---QVyggrs----------------tiqgaT---------SGTaSTIAFTPLQGLEI 458 Amphimedon quee...
CDS43033     477 TADSKTKARVSKALQQKLSKygglstmpttalgaatssavwgtassvrrggteT---------AGTaSSVTFTPAQGLEI 547 Echinococcus mu...
XP_004342635 491 MVDNKSRITLSKKLQKEVQRERllaGNMtalahgagvgq----asaaasaapaV---------SGT-ATVAFTSGKGIEI 556 Capsaspora owcz...
3JCR_J       463 VNP 465
EDQ92511     464 VTt 466 Monosiga brevicollis MX1
EGD74347     472 VSk 474 Salpingoeca rosetta
PDM66803     466 VNP 468 Pristionchus pacificus
EGT47772     474 INP 476 Caenorhabditis brenneri
EJW82755     460 VNP 462 Wuchereria bancrofti
XP_002109132 463 VNP 465 Trichoplax adhaerens
XP_003382952 459 VNP 461 Amphimedon queenslandica
CDS43033     548 VNP 550 Echinococcus multilocularis
XP_004342635 557 VNP 559 Capsaspora owczarzaki ATCC 30864
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