Conserved Protein Domain Family
DUF2053

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pfam09767: DUF2053 
Predicted membrane protein (DUF2053)
This entry is of the conserved N-terminal 150 residues of proteins conserved from plants to humans. The function is unknown although some annotation suggests it to be a transmembrane protein.
Statistics
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PSSM-Id: 401642
View PSSM: pfam09767
Aligned: 32 rows
Threshold Bit Score: 130.862
Threshold Setting Gi: 284087356
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_001773351   2 TFFHFFNCAALTFGPHAIYY-----------KATPLSEY-DTLGTCIKAAIVYLVTTLVKLICQ---------------- 53  Physcomitrella ...
XP_015791013   2 SFYYFVNCISLTFLPLFFVY-----------KFTPLSEY-GSIYRCSFALFAYLVVQIVKLTIM---------------- 53  two-spotted spi...
EDO05310       7 A-----TCLVLIVSPYWIVY-----------TKSSLAQNvNNGWTALRSCGYYVAANAVKVFIM---------------- 54  Babesia bovis
EDL44650       2 ALFHFVNCSLTAFTPYYIIY-----------DGFKLSKNaGSTKLFFLVCFYYIVSQILKLFTL---------------- 54  malaria parasit...
A0C428        30 AFSHLINCLLLAFGPFFVVY-----------KARSLAEQ-GAYKTVLISILGCLLTQFCKLFLL---------------- 81  Paramecium tetr...
XP_003284712   2 TFLIFTSCALLIFGPIFVVA-----------NASVLSQV-KYGHYFLFGFLSNLGWQIAKLFIL---------------- 53  Dictyostelium p...
Q54BM6         2 TFLYFSSCLLITFSPFYIIY-----------KSLKLNEI-KSNQLILYGFIGCIFTQFLKMLII---------------- 53  Dictyostelium d...
XP_004359663  65 TFLYFTSNLLVTYAPFYLLY-----------KSTSLNEF-KSFNIILQALCGNLITQVAKMMLL---------------- 116 Cavenderia fasc...
EFA83128       2 TVLHFLSCVSITYIPLYIAY-----------KSTKVGEF-KALSTVGYGLIGNILTQLAKMMFL---------------- 53  Heterostelium a...
EFC41026       2 TFSHFISTFALSFISPYIVYfskqssskgekENSSIGTE-RRFSNVVLGIMAFGLTMFCKMFLIaivirgnenqqlqsga 80  Naegleria gruberi
XP_001773351  54 ---------ATF-LQVS--EHDDFdlgQELLKGLIGFLDVGGLYYALTQ-VSHRSisqD---HKFQAVG--LGWAFADAL 115 Physcomitrella ...
XP_015791013  54 ---------ATLpLPAFlfDH---------------LIDCLGLYYVLVK--QQKAsliQ---VKILGVA--VGWSFGESI 102 two-spotted spi...
EDO05310      55 ---------ATG-IPELv---GNYiftEDIVMAILNSALYLGIMLPLRG-KTNAStnvN---NIVLGIG--IGWSVPENI 115 Babesia bovis
EDL44650      55 ---------AFFsIGLL----QNMnlfNIIFQECANFIDLAGLYYILSH-KHTNTinlK---ERILSVG--LSWGFYESV 115 malaria parasit...
A0C428        82 ---------ASL---------SVIteqLIHIKLLFDLIDCYGIIL-----VAKQKtniDdkiSRVFAIA--IGWALMDCV 136 Paramecium tetr...
XP_003284712  54 ---------GSF-YPFF--DMEIYdpvQEIIKIVGMISEIIIVYFTLRY-LLKEKnkaNiskHKIIVLGftLGWFTVGSL 120 Dictyostelium p...
Q54BM6        54 ---------ATF-LPSF--NTTSIgiyPEIIKIICNVIDLFSMSLVLK--FAEFSgskD---YRILGIG--IGWSFSHAI 114 Dictyostelium d...
XP_004359663 117 ---------ATF-FPSF--DTSTFslyQGLVQCLSVVMDLFAIYF-----VTGFS-------QSKFAIA--TGWALADAL 170 Cavenderia fasc...
EFA83128      54 ---------ATF-LPSF--DSTIFsvlQELVRLVNVLIDLFSIYTLLQMsHAPKD-------VRAFGIG--LGWVIAD-V 111 Heterostelium a...
EFC41026      81 infddnkqiATLgFGFFi---------TEILKTLIGSLDLIGMFFILSS-----KwllGdqtSQLYGCA--IGWTMGDNL 144 Naegleria gruberi
XP_001773351 116 LHRLAPLWVGAKGLEFTWEHLLQGLESNANLVLTVSLAAlgsLMWL 161 Physcomitrella patens
XP_015791013 103 LTRLIDFYVNAKSMQFDWRHIISAMDANVTLIQTICTCT---LIWN 145 two-spotted spider mite
EDO05310     116 GRTVFQTVSTLSNADETNMFLYEAFQAHLHILVSIIVTA---LLFL 158 Babesia bovis
EDL44650     116 ATNFFPFFIGGRSMDFSLKHIYRSISANTFMFSNLSKTC---LLFM 158 malaria parasite P. vivax
A0C428       137 MKHLFTFIPNATTDEFTWTFILRGFTANLEFFETLFLVG---LLqs 179 Paramecium tetraurelia
XP_003284712 121 LTQFLPLF-NTLGVEFNWVYTFNALDNNIKLLEQFALNT---CIYL 162 Dictyostelium purpureum
Q54BM6       115 MSQLIPLLMGTLSISFDFSYYLDSIESNFIAIQQLVVFK---LLYL 157 Dictyostelium discoideum AX4
XP_004359663 171 -QRLPQLWLGSLPLEFDSIHLIRSFESNTHTAHVIAIIL---LIgh 212 Cavenderia fasciculata
EFA83128     112 LPRFFSLWVGALPLEFDANQLIGSLQSNVNCAHTVAIVL---LLas 154 Heterostelium album PN500
EFC41026     145 FNRLLPLWFSTRGLQFELKSLQMGVYSNIVMLEWIAVAT---FVFL 187 Naegleria gruberi
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