8F2U_N       174 EVYkPRRKYKRhQgae--elLDEESR----------IHATLLEYGRR--YGFSRQSKMEK-------------------- 219 human
XP_001743134 189 EHYaPKRRYRA-Palg--saPDEATA----------VETTLLEYGQR--YGIRRKQAKAK-------------------- 233
XP_046457734 193 KLFlPQRKFKK-Vqgq-slpIEKE------------VVSTLMEYGYNk-VNLLDDTQQLV-------------------- 237
Q4DS58       173 SRRrPAPLRQR-VsevadrhSVEKPQggqnfsrlvhVSSALLEYGIR--YEMRDSVLMLR-------------------- 229 Trypanosoma cruzi
EAY21709     158 KFFpPRRFYKR-Sawn--esLPEIKQ----------IETTLLEYGKI--PTSISAESQKG-------------------- 202
XP_002905774 190 DAYaPKRRWQY-VaaegeieENEDAL----------IQRCLLEYGER--VTVATDEEPMI-------------------- 236
2_pfamImport   1 DVYaPKRRWQY-VaiagkqeESEDAL----------IQRCLLEYGERvlVADNGDIEVEM-------------------- 49 
A0E0M3       159 DLLqDNRQTKN-Lkk---lsKKDPLR----------VYSTLIEYGDL--SSQRTYNKFCAlis----------------- 205 Paramecium tetr...
XP_002645675 215 NQYsDAIRMLK-Fdhs--iiRDDWVT----------GRQMLYEYANYsrTGRRTFPSTVA-------------------- 261
XP_001021302 167 QTV-DKRQTKN-Vnak-nlqLNDPIR----------IYSTLIEYGDI--TAIKTYNKLSGvvsgkidleneiqkqtkgks 231

8F2U_N       220 ---------------AEDKKtalpaglsateK---------------------------------------------ADA 239 human
XP_001743134 234 ---------------SAKEA-----------Ava------------------------------------------aSLG 245
XP_046457734 238 ---------------EKTMK-----------Se----------------------------------------------- 244
Q4DS58       230 ---------------HVSRG-----------Vvaed-------------------------------------eevaREV 246 Trypanosoma cruzi
EAY21709     203 ---------------NPKMA-----------K---------------------------------------------MSA 211
XP_002905774 237 ---------------ETKPE-----------G------------------------------------------------ 242
2_pfamImport  50 ---------------DTREE-----------Delp---------------------------------------idfVAQ 64 
A0E0M3       206 -------------giQKQKQ-----------GnqqnvsavnsktqqnptlafqqnlfldevpekkqtnqnqqvtleqLTN 261 Paramecium tetr...
XP_002645675 262 ---------------DGYEI---------------------------------------------------------VRR 269
XP_001021302 232 kstrdtsepgkskkeKKEVD-----------QkindiifydqassksqkvevdtgrinaliasssqqpqfmslnqanAEM 300

8F2U_N       240 HEEDELRAAEEQ--RIQSL----------------------------MTKMta--mANEESRLT------ASSVGQIVG- 280 human
XP_001743134 246 ADDTDDAAAEEEarRLDQL----------------------------MQTMg----EAGEDKVS------KARLGSIIE- 286
XP_046457734 245 --------------------------------------------------------KKLENRAI------AHKVSNLIH- 261
Q4DS58       247 REQEEEEMREER--MFEMI----------------------------IKKMrd-hrERTDGKMS------LSKVKTLMQt 289 Trypanosoma cruzi
EAY21709     212 KAQQEAAENQNK--REEEL----------------------------RQTLstmnrQAGDSAID------GSIIANSLV- 254
XP_002905774 243 --------------KYQVA----------------------------FLAQiasqaAAVAVSGA------KPKGGSMRGl 274
2_pfamImport  65 MASQAAAVARSGtmKPQGK----------------------------FLSFnrrrlKRSDRRAE------KFGRHYQAAa 110
A0E0M3       262 LQKEKMQQAQAQikEMSQI----------------------------AGPSaeatlNEEEGRKFqklqrrNSIAGQSLSq 313 Paramecium tetr...
XP_002645675 270 PNPELVSAAVRD--KLDIL----------------------------MDTImnsltERTHENVL--------AMIDLVDe 311
XP_001021302 301 NDRIKPQEATFKrgKLAQMtapqfaqvqigtssssndgslqsqltqaLNAMnqqsaTTTGSAGA------DTQTQAILEp 374

8F2U_N       281 -LCSAEIKQIVSEYAE------KQSELSAe----eSPEKLGTSQLHRRK------------------VISLNKQIAQKTK 331 human
XP_001743134 287 -QSTNVISKLSDEYRA------HAAEVAKa-----DEGRQGGVAAHKRA------------------VQSLNKRIDAAQS 336
XP_046457734 262 -QQAGFISQTIDDYTQ------RQNEREGer--deRTHLEERNKKTSEA------------------LERVCNQIASQQQ 314
Q4DS58       290 tKISESLQKLSAEYHA------RQQERQMqq--dsVQAMQRKLQQKQEA------------------TVRYRQESEALRL 343 Trypanosoma cruzi
EAY21709     255 -NQAGTILANQNIFDE------SETKLSMyteadlRQQHETTVTRLKEH------------------LQTIKAQGRKVQS 309
XP_002905774 275 rRTKKSDPHFDRQYQK------AMKQ---------AKEEQQTLLNQRRE------------------REAMLLQNVEHEL 321
2_pfamImport 111 dQAREEQQTLLRRRRE------REAKLLQrl--vsAPDEKERDSTNGRV------------------EASEESMLQSAIE 164
A0E0M3       314 lISKEKIAEGLKQQTQ------EEDQEVVntvnikLQEKIILEQQFKLQqq---------------nLNNLEKAIEQDMQ 372 Paramecium tetr...
XP_002645675 312 lRFAVRLSQIEIRFYQ------ECGAFHKmys-qfHDEGSAFLKTNAVA------------------YEINPSDPIKVTE 366
XP_001021302 375 eNDVELQVEGNNNFTDiraggrRQSVVGAnlmeliAQGQDDIKEAITKTaeadespeiefaniikteKEFHEKQVIALNQ 454

8F2U_N       332 HLEELRASHTSL-QARYNEAKKT---LTELKTYSEKLDKEQAALEKIE--SKAD-----PSILQNLRALVAMNENLKSQE 400 human
XP_001743134 337 DLDALQAQRDET-HRRYESAKAR---LAEAQTEHAQLEEEARQLDGLEg-DESN-----KPIIEKLRTLLATMDDLKARQ 406
XP_046457734 315 VMDQLKAKIGDLiASEEV--------LEQQKKSLAALE------------TEEN-----RQTLDQLDRLVSQNEAANAQR 369
Q4DS58       344 QCEEAVQQLAEA-QSRLQDAKAK---VARRTAKWTEYMHNLQDVYQHVmaDPVR-----GKLLQKLQGLLDQKEEQRLLL 414 Trypanosoma cruzi
EAY21709     310 TSEDVQSELDAA-TKSLQDARAKnadLKSKIKEAAAVV--------------ED-----AQHTEAIMHAMTLRDDNRKNI 369
XP_002905774 322 QVQQLIEEKKTL-DDQTKESTVR---AAALDEALSACKQQLTEVEAQTpkDEDA-----QAHLIKLRQLVMKNETLKREK 392
2_pfamImport 165 KLKKHEQELIEEkKHLYRKVGTCnsqAAALDEAFLALKLEVEVVEVQTpkDSIA-----VANLAKLWQLMKQKEEHKQEK 239
A0E0M3       373 EVEQLESQNNQL-TEQINEEKSR---LTKIVDALKVIDSKT---------KKAN-----QVDIKRAEEQVAKKIELKEQK 434 Paramecium tetr...
XP_002645675 367 CVEDIKERFQILnKYLLGNE------IVEKEKRSRNLRQNYDEYDPLGyyHADN-----SHRADVLDKEVKKL----RLR 431
XP_001021302 455 KIADLQKKLQEE-KEELIKIKEEeeeKENYYDQHTGLDNELKETRQLIekKLQQakvksKELIAEAEMNVQKRNALKEQK 533

8F2U_N       401 QEFKAHCREEMTRLQQEIENLKAERAPRGDEKTlssgeppgtltsamthDED-----LDRRYNMEKEKLYKIRLLQARRN 475 human
XP_001743134 407 GAFKATCQAEMERLQGEIEGLRATGAIQVDDER----------------AQA-----VQQQLQEEQARLDKAKISASKRN 465
XP_046457734 370 KQFKNQCKTELEELQSRNEALLSKEEEAPANQD----------------H-------LKRQVDSAREQLAGALKILGEKN 426
Q4DS58       415 EETRRDGKQRLKAAKANCVALAERSANAEPGVD----------------DL------WEKERAKYVAELRRKEAELSAIN 472 Trypanosoma cruzi
EAY21709     370 EEFAAQCKAEIAEWNERIAALKAKAEGSGDANA----------------IK------LQQALEQYTKDWQRKQELVAEKA 427
XP_002905774 393 NEFQTKCRLELEALKERVEKLKLQVAEDASNQD----------------EEAqrlneIEQMHAQMAQKHRDMMVVAAKQT 456
2_pfamImport 240 VECRAKCRLELETLKDRVEKLKRQVAMHENKQD----------------DRAlgllkMEEMHAQMALKHKELKHAAAQRT 303
A0E0M3       435 TELKKEIKQEQQKIEKEKEEALRNMPQENDQEL----------------LKE-----MKSQYNQKKEKFEKKFQQFQLLN 493 Paramecium tetr...
XP_002645675 432 AMLCNEIPKELDPVFEAYNNLQKKKEDSFPEPT----------------EEH-----IGLFQDIDYALVDDITFLMT--- 487
XP_001021302 534 TKLRKEIKIQIQESEKEMEKTKKEAAIMEDQQD----------------QGEe----FSEDYIKKKEKLNKKTEELSKYN 593

8F2U_N       476 REIAILHRKIDEVPSRAELIQYQKRFIELYRQISAVHKETKQFFTLYNTLDDKKVYLEKEISLLNSIHENFSQAMASP-- 553 human
XP_001743134 466 RQVAYLERQLDQIPSRSELKQYQRRFVELYEQINAKHRETQHYFALYNTLSDTKSYMMNENSLLQSIQETFPKAVLST-- 543
XP_046457734 427 VNLMKLRRQLDAVPGNSELNQYQRRFTELCTQVNEKQTELNGYYLLYNTLEDTKVYLNKELSLLTSIHDSFSQSMTSS-- 504
Q4DS58       473 QKASDLLRRTDAFPTRLELMQIHMRICELNEEVSSKYEELRAAFARHNTRMEILKCLESEDVIMTQLAGKMEWCLRQPsw 552 Trypanosoma cruzi
EAY21709     428 REVLKLRMEYDLYPTMAELSQYSRRLKELSALSLSKIVEIKKCTQLLNSLISSTNILEQENTLFNNIIQNFQDSKKDT-- 505
XP_002905774 457 RALHLTMKQIDEIPTRIELVQYEKRFLELYDEVALTLDETRKYYCVYNTLKTTHDFLEKEISLINSINDNFGVAMGSK-- 534
2_pfamImport 304 RAVYRKLKQIDEIPSRIELVQYEKRFVELYDEVALTLDETRKYYCVYNTLKTTHDILEKKISLINSISENFEVAMDSK-- 381
A0E0M3       494 QEIVVLERKLESFPQPSEIAQYHQRFLELYDSINEEMESNKKLLLKYNNLLEVKQLAAQFVDIYRTFKENYTNNLKDK-- 571 Paramecium tetr...
XP_002645675 488 -SVTNMLDELDQLPPIVDKIDYDFRQATR-AYANDCHNILSDWYWKARILKEERRNLHRKMRDLRMDAKIVKHKIFFA-- 563
XP_001021302 594 QENAVLQRQLENFPSASEIAQYQLRLLELYESISSESEKEKDNYIRYNNYCDIKTQLVQFVEIMKAFKENYQVHKKSK-- 671

8F2U_N       554 ---AARDQFLRQMEQIVEGIKQSRMKMEKKKQENKMRR-----DQLNDQYLELLEKQRLYFKTVKEFKEEGRKNEMLLSK 625 human
XP_001743134 544 ---NNKRAFLDQLAKIVDGIDNNKERLREKEGSARERR-----DQLSQVHLALIETERRYFKAVRDYEQDMKRNAKLAAQ 615
XP_046457734 505 ---AGKGEFLQQMEKIVTAVRQNKNKIEKQIEMLTEKH-----HDLGRCLGQFAVEEHQYRDTLKAISHESHKYKQLMSQ 576
Q4DS58       553 vskNVSVELIREQERVVTQLRDSLDAVLRRNEDVTSKM-----TAARKEYESLLVRKQQHRDMLGLLKQTIEEQNARMEP 627 Trypanosoma cruzi
EAY21709     506 ---GLQRNLISQTTSISNKTKEEKTRLDGEIEKKAKEL-----QTKEEQHRKLLETQRRYFQAVKEYQEAQDQLADLLDE 577
XP_002905774 535 ---TATQAFFMQIDNIIQNVQGTVTKQQNARDDHQGSV-----ETLDSKYQLLLEQERMYVNAIREFQKECEKNEKLVAQ 606
2_pfamImport 382 ---TATQAFFVQVENIIENVQGLVRKQQAARDDFQSNV-----DILDSKYQLVLEHDRMYTNAIHEFQKECEKHEKLSLR 453
A0E0M3       572 ---KGKIELSQNLDSTYKQLQKQLQLYQEKLQQSENKR-----QSIMEQYRQALAIEREYYKLLKEIKFEYEKYEQYTNK 643 Paramecium tetr...
XP_002645675 564 ---KPESTLLMKLNGVLGSVTYTLKRWETESMEFKIDWaskiaAKEDREAKEAKIKEEKRLQALEDARAAKQAKIVKSNK 640
XP_001021302 672 ---SGRTKFIGDLTEAYKGLEENCQKALELLTKIKNQR-----EKKMENYNQLKVQERDYFKLLKDFRLELEVNETLQQR 743