Conserved Protein Domain Family
DRY_EERY

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pfam09750: DRY_EERY 
Alternative splicing regulator
This entry represents the conserved N-terminal region of SWAP (suppressor-of-white-apricot protein) proteins. This region contains two highly conserved motifs, viz: DRY and EERY, which appear to be the sites for alternative splicing of exons 2 and 3 of the SWAP mRNA. These proteins are thus thought to be involved in auto-regulation of pre-mRNA splicing. Most family members are associated with two Surp domains pfam01805 and an Arginine- serine-rich binding region towards the C-terminus.
Statistics
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PSSM-Id: 401629
View PSSM: pfam09750
Aligned: 70 rows
Threshold Bit Score: 88.5263
Threshold Setting Gi: 552834112
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_005848655   30 LSIFGVPAEIFCDAAAAAELEEGSHLVPCW--GDPDDLTDRWDARLLL-DPLSLAA-----SARQRRQPPSSAAAEEAaa 101  Chlorella var...
ERN09155       29 LEVAGRHAFLFDDDSTSQFVDSSDALVPWN--GDSHLSIDRYDVRHLL-SDLSSLR-----KKQKLPSSKSPDAVSES-- 98   Amborella tri...
XP_004248293    3 LVVVGRHALFFDDDSLAAFVNSGDALVDWN-----SLQIDRYDVRHLL-SAPPPSRr----RSNSSSSSNLVDASIQL-- 70   tomato
CBI26667        3 LEVLGRHALLFDDDANSAFVNSNDALVEWN-----SLLIDRYDVRHLLpTPLPPLKr----RRHHSSALPAEISQLEL-- 71   wine grape
EEF32910        3 LEVIGRHALLFDDDALAAFVNSPEALVDWN-----SLSIDRYDVRHLL-SSPPPPRnrhhrRNQHRSPSHNLDDSLES-- 74   castor bean
BAH19551        3 LEIVGRHALFFDDDSMATFVNSPTALVDWN-----SLFIDRYDVRHLL-SSPPP-------PRIKRRRPNSNDADLES-- 67   thale cress
VDC86908        3 LEIVGRHALFFDDDSMATFVNSPTALVDWN-----SLFIDRYDVRHLL-SSLPP-------PRPKRRRSVSDDPDLDA-- 67   field mustard
XP_009412426    3 LAVEGRHALLFDDDATAAFVNARDALVPWS--GDPALLIDRYDVRHLL-DRIPPRPpv--rAASRLCEVPAVDGVTSS-- 75   wild Malaysia...
XP_004969650    3 LEIVGRHALLFDDDATAEVVNSGGSLVPWAaiGAADLLLDRHDVRHLL-DCVPPRPrr--aYSAAILYVPSSDGVSEA-- 77   foxtail millet
Q5N8K0          3 LEIVGRHALLFDDDPTAEVVNSGGSLVPWAavGADDLLLDRHDVRHLL-DRVPPRPrr--sYSAALLSAPSLDGVSEA-- 77   Japanese rice
XP_005848655  102 laaagasweELERERYRDL--------DPSREHElqRHGRLLPPAGRMYFSGARegddqaeegyqgalpppgLPPpAaSr 173  Chlorella var...
ERN09155       99 ---------DLDFERFRDL--------------------------------R---------------------KSdDpEg 116  Amborella tri...
XP_004248293   71 ---------ELDKERYLDLp------lPSD----------------------------------------------EpDl 89   tomato
CBI26667       72 ---------ELDQERFLDLp------pPSD----------------------------------------------EqEl 90   wine grape
EEF32910       75 ---------DLDHERYLDLp------sTSDD---------------------------------------------EqDl 94   castor bean
BAH19551       68 ---------ELDHERYLDLpsespspsDDD----------------------------------------------EhDm 92   thale cress
VDC86908       68 ---------DLDHERYLDLpadspspsHDESGKDceLRRNLSVLSIVDLVQTLG------------------SYV-RdDm 119  field mustard
XP_009412426   76 ---------QLDRERYLDLp------lSGPDA--------------------------------------------DpGg 96   wild Malaysia...
XP_004969650   78 ---------ELDRERYLDLp------dADGDG--------------------------------------------EdEg 98   foxtail millet
Q5N8K0         78 ---------ELDRERFLDLt------aDDFGG----------------------------------------------Eg 96   Japanese rice
XP_005848655  174 faavahDysgardgggtgqyAAVGFSYGD 202  Chlorella variabilis
ERN09155      117 ggrgaeMasg--------syQAVPFSYGN 137  Amborella trichopoda
XP_004248293   90 eegdesAdag--------ayRAVGFSYGN 110  tomato
CBI26667       91 dnglekAdaa--------gyHTVAFSYGN 111  wine grape
EEF32910       95 eteaeaKnag--------gyNAVAFSYGA 115  castor bean
BAH19551       93 nedsanTnad--------gyRAVSFSYGS 113  thale cress
VDC86908      120 ndgsasTnaa--------gfRAVPYSYGS 140  field mustard
XP_009412426   97 dddargSlsgttk-dsdgtyQAVPFSYGN 124  wild Malaysian banana
XP_004969650   99 sgdaapSgngtdt--rqsdcSSVPFSYGS 125  foxtail millet
Q5N8K0         97 sqdavsSgngtdt--gwadyNSVPFSYGS 123  Japanese rice
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