Conserved Protein Domain Family
HVSL

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pfam09749: HVSL 
Uncharacterized conserved protein
This entry is of proteins of approximately 300 residues conserved from plants to humans. It contains two conserved motifs, HxSL and FHVSL. The function is unknown.
Statistics
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PSSM-Id: 401628
View PSSM: pfam09749
Aligned: 102 rows
Threshold Bit Score: 145.111
Threshold Setting Gi: 388853555
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_009154394  67 PPLP-PSFASLYATNV---RTFAADD----PSLHAGRKR------QIPHVAGNWPTHVFLEWTPSRDQVEILDGVID--R 130 Exophiala derma...
CCF52727      69 PPLEaDSLQRQDDDSP--------SDltpaPASNS----------SKKVARGDWLCYCFVDVPLDPSSSALIRDCHK--H 128 Ustilago hordei
CBQ72880      62 DALSnERLSRSSS-----------------PARAIGNS-------TGKVVKGDWLCYCFVEVLVDPSLGRCIQDSHA--H 115 Sporisorium rei...
CCD26032      17 PPIP-DSILNKYHIEPnlaKYDIEQT----SPSQNKSTKvmylrsSQRKLDQFWQAFIYLECKPTRGDRQFLSQIISttN 91  Naumovozyma dai...
Q6FJQ8        61 PPIP-SSVYDKYQIPPntdKYIERTD----NGMSLGAIKgs---dVFKRNIGKWSCFLYIEYRPSSTEREMISKTLS--Q 130 [Candida] glabrata
EDO19325      43 PTVP-STVLDKYYVSPnilKYTEEMSnlv--------------giKTGFRTGQFRSFIFLEWRPTSLQRQQLVKSIN--Q 105 Vanderwaltozyma...
XP_002173037  30 lsLP-EEFENKYRSSP-----RLLDD----PVFHQGRKR------TFAHVEGAWTTQSFIEVKLTRSLSSQLQQILKseI 93  Schizosaccharom...
EPY51754      25 PKLP-DFIKDLYRKKR-----KTFDS----PNFHEGRKR------TKAHVEGLWAVQIYLDVDFDNSSKQKIQEIIA--- 85  Schizosaccharom...
EXX60975      82 PPLP-SDFLQLYPDKKrkdYTKHIDD----PSKHQGRIR------SKPHVEGDWATHVYVDVTLTEEADHIINKIEE--L 148 Rhizophagus irr...
1_pfamImport   1 -PLP-DVICSLSDPTNt----EYNND----PSKHQCRIR------SFDHVKGNWATFLYIPY-PEEFSEELKINVFD--L 61 
XP_009154394 131 VQQRNlgdiadsgggTPSVKLHSFLRS-----------------ELGALL----------------PLHISLSAPLVLRT 177 Exophiala derma...
CCF52727     129 LQEQL----------GTSHTLLDLIHS-------------------DASPgadpa-------eeagYLHVSLTRPFTVRS 172 Ustilago hordei
CBQ72880     116 LQEQL----------GTKHTLLDLRHS-------------------DHPTtdegasaanpspssqgQLHISLTRPFTVRS 166 Sporisorium rei...
CCD26032      92 NNAKLhtsm---tnnGTALKFSPLYRS-----------------KLGSPQ----------------NLHVTLTPNIPFAS 135 Naumovozyma dai...
Q6FJQ8       131 FNQSWqk------kfPGTDIFEPLHYT-----------------TLGVPV----------------PLHISLTKNIPFDS 171 [Candida] glabrata
EDO19325     106 FNENLtk------tkGSNFRFDPLFIS-----------------SLGSPE----------------PLHVSLSKSIVCES 146 Vanderwaltozyma...
XP_002173037  94 AIEERdd------gtPKSNDWVPLFFS-----------------ELGLAK----------------PLHLTLSSMDCLDY 134 Schizosaccharom...
EPY51754      86 ----------------SQSEFRSLFTS-----------------EFGVVR----------------SLHLSLSELFRIAS 116 Schizosaccharom...
EXX60975     149 AKEVV---------------------SkdgikiisciedhqdnnSLNELDpngh--------ceetKLHISLSKPLFLKY 199 Rhizophagus irr...
1_pfamImport  62 FQFSG---------------------Id----------------GWNVVD----------------SFHMSISRTSAIPH 88 
XP_009154394 178 D-QKSAFQERFCDELRttrSSTTttdgcrsgnssrlglQPF--TVHVT-GLDWVANQDGSRWFLVLKLSRPDN--DELNT 251 Exophiala derma...
CCF52727     173 S-ERDEYAKIAKAELQrlkETIGr--------------NSF--PFSFS-RIAYLNNDDASRHFMVLEVGSGr---DQFHK 231 Ustilago hordei
CBQ72880     167 Y-ERDEYVKVAAAEVQrlkATVG----------------SF--PFTFS-RIAYLANDDASRHFMVLEVGAGr---DKFHR 223 Sporisorium rei...
CCD26032     136 EaLRDSMLQVLSDKIN---KCKI---------------RPFvlEFESArACKLLRSVVNDKLFLALDVKEEik-rNQLME 196 Naumovozyma dai...
Q6FJQ8       172 EtQRDRFYNILVPKVAqlrQH----------------------LVQFEdTLRFYGSPQTTSVFLGYNVAQSvk-dNIIKD 228 [Candida] glabrata
EDO19325     147 ItQRNLFYRELKKELQ---SVQI---------------QPF--TLTFTnKPLVLTAKQDSSMFLCLEVNRShr-tKILKP 205 Vanderwaltozyma...
XP_002173037 135 E-SKESFRVQWKQTLS---SAHF---------------QPF--SIQLG-KVLYLVNEQQTRGFLAWRIHFDe---HHLKP 189 Schizosaccharom...
EPY51754     117 D-ERKAVLTIWRRECQhlqHRAI--------------------RYKLQ-DPCLLFNDDRTRMFFVLKATFESA--DLLKK 172 Schizosaccharom...
EXX60975     200 H-QIEHFWNKLRNGF----LNWK----------------RF--SLSFA-NITSFSNDDKNRSFLAL-EVGKGS--NELKS 252 Rhizophagus irr...
1_pfamImport  89 H-YIEPLVDAIKDSV----RTFN----------------TLd-LMFSS-KLKFYVNDEKTRSFCGF-QISCPLliTKLQY 144
XP_009154394 252 LLAVCNEVA--------RR-FGLQPLYeedtkqeevqeqdgtkrghqhqqhqhqrqsregtqkkqrqkekreikagndKS 322 Exophiala derma...
CCF52727     232 LSTALSKVL--------HRaFRAKAYY---------------------------------------------------EE 252 Ustilago hordei
CBQ72880     224 LSTALSTEL--------RRaFRAKAYY---------------------------------------------------DE 244 Sporisorium rei...
CCD26032     197 IHEIIDETL--------KK--VIPEYYsqswknra----------------------------------------kdfyl 226 Naumovozyma dai...
Q6FJQ8       229 ITDNIESALidsglsesDKmVTVPSFS----------------------------------------------------- 255 [Candida] glabrata
EDO19325     206 IQDAISSAL--------ETtFSNQSDIimn---------------------------------------------fqvSN 232 Vanderwaltozyma...
XP_002173037 190 LCQKINDLN--------IS-FGMQPLR---------------------------------------------------PD 209 Schizosaccharom...
EPY51754     173 LLEISNNLM--------EK-YEGKELR---------------------------------------------------KD 192 Schizosaccharom...
EXX60975     253 MVDHVNKVA--------ED-FRQKPFY---------------------------------------------------EN 272 Rhizophagus irr...
1_pfamImport 145 YVDRINQPL--------KD-YGCDGYY---------------------------------------------------SN 164
XP_009154394 323 HAFHISIAWALHnpnpdyfgnD------DHPVRMSQrstlah---leeegiNEQLRGL--EI--------AF--SSLKLK 381 Exophiala derma...
CCF52727     253 ARFHASTSCLEItktldddaePpelreaGEALGPRFsdivn---------------dvekKWgpqlrkhpPTwaARVGIQ 317 Ustilago hordei
CBQ72880     245 ARFHASTACVLDs-------tPdqsdhaTQALASRFstiva---------------dieaEHgprlrqcrPVwaTRIGIQ 302 Sporisorium rei...
CCD26032     227 nnaHMSLAESNTvps-----------rmVKDFKKLQdllsynnnpkncndgDKETIQEenNL--------SFqiRTLKVD 287 Naumovozyma dai...
Q6FJQ8       256 ---HMSIAkls---------------naPKDILDKVgya----------dsnQMAKQIqdYVeispnqqpVFyvSSIKMN 307 [Candida] glabrata
EDO19325     233 EYLHMSIAQMTNcppssanlkSssidwePFHGLDEI----------------------------------KVpcKEVKCL 278 Vanderwaltozyma...
XP_002173037 210 FIPHISFCWRKT---------NpkeceaWSSAISLYevpskfdnlvsaiedLLKSNNT------------NIpvKSVKLS 268 Schizosaccharom...
EPY51754     193 FLPHVSFAWAHA----------------KQGDFEAWescdrenlrfieletLLK------QFesamlksvSLenNSMKMV 250 Schizosaccharom...
EXX60975     273 PRFHASILWALG---------E-----------TSIdrslcda--iketeyfESITQH--VF--------NI--ENMVCK 318 Rhizophagus irr...
1_pfamImport 165 PSFHISIAWTLG---------Nifd-qnWKMLLHKFqihwl-------evftNCPELF--SF--------KA--NCLACK 215
XP_009154394 382 IGNSVIDIP 390 Exophiala dermatitidis NIH/UT8656
CCF52727     318 VANRITYVD 326 Ustilago hordei
CBQ72880     303 VANRVSYVD 311 Sporisorium reilianum SRZ2
CCD26032     288 IDRQTLTIP 296 Naumovozyma dairenensis CBS 421
Q6FJQ8       308 KNRELLTIp 316 [Candida] glabrata
EDO19325     279 INRQLYSIP 287 Vanderwaltozyma polyspora DSM 70294
XP_002173037 269 TGGYldtle 277 Schizosaccharomyces japonicus yFS275
EPY51754     251 MGHKIHSVT 259 Schizosaccharomyces cryophilus OY26
EXX60975     319 IGNKTFTLD 327 Rhizophagus irregularis DAOM 197198w
1_pfamImport 216 CGNRLFKFE 224
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