Conserved Protein Domain Family
CPW_WPC
?
pfam09717: CPW_WPC (This model is not part of the current CDD release)
Plasmodium falciparum domain of unknown function (CPW_WPC)
This group of sequences is defined by a domain of about 61 residues in length with six well-conserved cysteine residues and six well-conserved aromatic sites. The domain can be found in tandem repeats, and is known so far only in Plasmodium falciparum. It is named for motifs of CPxxW and (less well conserved) WPC. Its function is unknown.
Links
?
Statistics
?
PSSM-Id: 519007
Aligned: 111 rows
Threshold Bit Score: 38.1148
Created: 15-Feb-2025
Updated: 28-Apr-2025
Structure
?
Aligned Rows:
Download Cn3D
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
XP_001613883  736 RDYVQVsCPLGW----NQTDDGWCEAPAdypphlRAA-CgGRVNFKYATP-LVRRNWSLVCRSDWPCF 797 
Q8ILH1        107 iNYEEY-CPEYW-----TQSEKYCIAPQs----yMGP-CsKKKSFQSFKK-EIKKAYAEECDIEWPLy 162  Plasmodium falciparum 3D7
Q7RIV1        120 EDFTKN-CPENW----ILKKKNICYAPKs-----yKDiCvKEKNFTNFSK-SEKKIWGDICNVNWPCY 176  Plasmodium yoelii yoelii
Q8I575        168 EDFSKK-CPENWi---HNIENNTCEAPKn----yAGK-CiRQKNFDHYSQ-SEKKVWAQICDINWSCY 225  Plasmodium falciparum 3D7
XP_001613883  162 EDLLEE-CPDSW-----TLKGNICHAPKs----yKGQ-CvRKKIFANFLR-EEKKAWADACDVSWPCS 217 
XP_018635269   94 VDYSAP-CPLKWhsrdVEGGGHLCEAPKn----yKGF-CeTNKSFDFYTA-DAKADWAESCEAVWPCH 154  Toxoplasma gondii ME49
XP_051623166  548 ENFYWT-CPSEW-----ELKDGQCIAPDy----yTGP-CkGSVSVSELSSdSAKATFSNKCRVAWPCI 604  Babesia bovis T2Bo
XP_002258851  279 QDFEGSvCPIDWvm-eKEEQYGYCKSPDe----yTGK-CiRKIKFSNMSS-KEKAIYSNLCDVRWPCK 339  Plasmodium knowlesi strain H
XP_001614511  274 QNFEGSvCPIDWlmeeEQQQGGFCKSPEs----yTGK-CiGKIKFSNMTS-KEKAIYSNLCEVRWPCK 335 
XP_002808631  308 QDFENSiCPLEW----TMKNEEYCISPEs----yVGN-ClNQINFINMTN-KEKAIYSNLCDVRWPCK 365  Plasmodium falciparum 3D7
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap