Conserved Protein Domain Family
Cas_Cmr3

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pfam09700: Cas_Cmr3 
CRISPR-associated protein (Cas_Cmr3)
CRISPR is a term for Clustered Regularly Interspaced Short Palindromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This highly divergent family, found in at least ten different archaeal and bacterial species, is represented by TM1793 from Thermotoga maritima.
Statistics
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PSSM-Id: 401587
View PSSM: pfam09700
Aligned: 18 rows
Threshold Bit Score: 199.993
Threshold Setting Gi: 74559418
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q8TVU0           10 FLVLPQDRAFFRRPEPFRAAAEs--VAESEGPKPWTVAGCVRNALLEVTDGDL---GEVLEYPRKlvrsapp-----gsi 79  Methanopyrus...
O28413            3 LVMKPYDSLLFREPRPFDVNNH---VARTILPLPQTLAGAVRSAIYVKYGSKV---KDLIGFGKE--------------- 61  Archaeoglobu...
Q7MTH3            6 IKLTPLDKFFFGQKKTFGDDNAnyfVYSSLFPQQTTLLGLLRYQLLQIAGEEIfkdNKIQDEHKAgeligkqsfspfvkd 85  Porphyromona...
Q47PK4           13 IAFEPHDTVHVRDGRQFSSRDSntaLAETVIPRPSTIAGAAASAYGGDLT------------------------------ 62  Thermobifida...
Q1CW30            6 FALLPRDGLSAKDGRGWYTSEVg-rGYSLPWPLPTTVRGALRAAWGHDAMAVS---GAVLAPDEWercse---------e 72  Myxococcus x...
jgi:Mmwyl1_2691   4 FVLNPLDPLIIRSSRPFEAISD---AEAAKFPPPSTIAGALRNIHGRTIGIDF---NDRNNQEQLn-------------- 63  Marinomonas ...
jgi:Hhal_0628     5 RYIEPQDVLFFRGNRLFGEPGNa--GAALMPPWPSVFAGALRSAMLSAAGADP---AQLRSGELPapldtv------lgt 73  Halorhodospi...
Q2JN53            4 FTLSPLDVWMFRDAKPFAPGERa-wANSSFPPSGHTLAGAVQAYLGQPLT------------------------------ 52  Synechococcu...
Q6ZEA9            4 YSLTPLDILLLRDAKPFTPGDRa-wAGSIFPPNGHTLAGAVRSLLPQNQT------------------------------ 52  Synechocysti...
A0B6W4            4 LRITPVDSWFFRDGRPFHLGEAtsdVGGLFPPSAFTVVGAIRAHLARSMGWRE---GKWSEEICRvlgd----------- 69  Methanothrix...
Q8TVU0           80 geaLGETALFlGTWVVEvrp--gaPD-RLERVWWPCPAHlar-------yePESGGEAVDLLRVEEvgdaa--iafsGHD 147 Methanopyrus...
O28413           62 ---EPEFEIL-GHFFYR-------YD-GKFELLVESPHD------------VTQNLGLVKPHRIDK-----------LGI 106 Archaeoglobu...
Q7MTH3           86 klqFGIIQSL-SPVFIIdkk--knDE-GKEEYFLPVGRRf----------qKENEKAPYNLLHLSC-------------- 137 Porphyromona...
Q47PK4           63 -------AVR-GPILGKq-----nPD-GRWCPYFPVPSDivv------vegKETTAQERAYYRLVKgsa-----vdgTDL 117 Thermobifida...
Q1CW30           73 vrlRHLVALR-RPLGES--------F-SLAHRMWPFPADav---------cVRDADGSEHLERLEPrp-------dgAAT 126 Myxococcus x...
jgi:Mmwyl1_2691  64 --sLLEVPVT-GPLAVKipldqsvSKlEQRHILVPKPADaqy-------faVDNKPTLVGLQPLQPnedegcdlpngLLP 133 Marinomonas ...
jgi:Hhal_0628    74 peePGTFTLT-GVTLARr-----qSS-GTAEPLHPLPADls--------veRDEATGECAVHRLTPq----------PLP 128 Halorhodospi...
Q2JN53           53 ------LRLR-GPFLCH-----------DERLYFPAPLHledgfplvpvpwLDERDPYFHC-HWDP-----------TRP 102 Synechococcu...
Q6ZEA9           53 ------ISLI-GPLLYH-----------KETLYFPRPLGfvgktpllplpwHDATSPLRSQMLWDK-----------TQP 103 Synechocysti...
A0B6W4           70 gydLAGLRFR-GPLLCRe------GD-RGPEMLYPAPLNl----------lGKRNDSGYEMRLLRPgeev----ecdLGR 127 Methanothrix...
Q8TVU0          148 EALRRRygfmtpkpprPGSDVETPGRY-VDTGTISK-ILAGRTPARRTPDLEDnvag--pgeLLRPELHVGVKLVGLKTA 223 Methanopyrus...
O28413          107 TILMDS----------EGIKFRPFNGF-LKFSGLID-YLQGRIAEDSVVERQK---------IFKKERRVGIALTKAKVT 165 Archaeoglobu...
Q7MTH3          138 ----------------QAGCPPIFGEY-KPKKGLAScWLSSK---SHTLLNEEd--------FFTKDERIGIRKDYEGAT 189 Porphyromona...
Q47PK4          118 AHVPGApesllelppqVTAKAEPLQGW-ISSEGLSS-YLNGTLFQDSTVASDYletmlageePLVPEHRIGIALQDRRIR 195 Thermobifida...
Q1CW30          127 LGPDDDdarealwhprRNSSGKPMAAPlFWPEARMMaWLRGAVEPSSETPD-----------ALTPRTDIHLAIDVETQA 195 Myxococcus x...
jgi:Mmwyl1_2691 134 LFLSQD----------IEGKPVSGPKW-WSLTDLLK-WRKGEKLEFSDIEKGGw-------tPTEPDIRTHVERDNETLN 194 Marinomonas ...
jgi:Hhal_0628   129 AGVASSqplerlpvlrRSDRGKPAAGYwLTHSGWQR-YCQGEPPPAEALVHRSa--------IWSSDPRLGIALKPEQRT 199 Halorhodospi...
Q2JN53          103 APLVSLrpveeepersQSSKKKKTGGY-LPFEVVQK-ALEGKGWDLSQAVKP----------PLKYEVRPHNTLQVSKRQ 170 Synechococcu...
Q6ZEA9          104 APLAPLetvs---qtdIKRDEKQARTW-LPLDVMMG-YLQTGAIKPEDWARPEded----sqPWTMESRPHNSIEAGTRQ 174 Synechocysti...
A0B6W4          128 VRLPTAe---------KIDGMKQLSGY-VNGDQLKQ-VLRGEVPEGRVIPREE---------LWGTEYAVGLERERDTRT 187 Methanothrix...
Q8TVU0          224 -DEGYLYAAR-FLRPGrsp---------------vdGGSLVGFLTVLAVPEDAwddgvledlpSPGGRLGRGRHAWVIPL 286 Methanopyrus...
O28413          166 -KEEHFYQVE-MLRFS--------------------DDCGIAVWVEDGVDFDD----------EGILGVGGERRFVKFEK 213 Archaeoglobu...
Q7MTH3          190 -NDDAFFCQR-YYRFKnfkevegektkvckqppvreHDFCFAVLLETHRDIKHee------lnKRIVYLGGERQPFLMDL 261 Porphyromona...
Q47PK4          196 --SGYLYHAT-HLRPR----------------------DGWVFLAEVVPHPERpk------peHTTVTLGGISRLAEVAE 244 Thermobifida...
Q1CW30          196 sQDSMLHSRE-VVELLrlqrhs--------grtpvlEEWALGLSCAWPAPASGa--------pRGPLGLGGRRRLSAVEP 258 Myxococcus x...
jgi:Mmwyl1_2691 195 sVDGQIFQTT-GLTMWqqpdq-----------pqnfPSERVAILAGIDGKVS-----------LQAMNLGGERRLADVTD 251 Marinomonas ...
jgi:Hhal_0628   200 aAESQLYTTE-GIRLC--------------------EGYGFLAAIAGSDPTSLp--------kQATLRLGGDGRGAFMSA 250 Halorhodospi...
Q2JN53          171 vREADGYFVEtCIRLQ--------------------PGWSLALSIEGWDPDREawdpl-pltqEAVLRLGGEGHCALLAP 229 Synechococcu...
Q6ZEA9          175 vKESDGYFVEnGIRLK--------------------ENWSLAIAVDPTTHQQLqsl-----pqPLSMRLGGEGHRVTLVH 229 Synechocysti...
A0B6W4          188 aKEAHLYSIN-RIRLV--------------------RGVHLIMGVEGIDEGLLek------ldGAVMPIGGEGRMGCVEM 240 Methanothrix...
Q8TVU0          287 ----RAGDWSDDVFPEVEEP--EGDLPGLYLETPTPFPEGDvrsssPGDRlkaeavlvrpgsprdrvLQVELEVSEvese 360 Methanopyrus...
O28413          214 reepECITNLRSKWKKIRDKinETGRLKIYLATPAILGAKG-----YSSK-----------------LDYDLLGDIgier 271 Archaeoglobu...
Q7MTH3          262 m---EVSEETFKLNIESSTLtsDEKHYTVVLLSDAMIEPKLle------------------------------------g 302 Porphyromona...
Q47PK4          245 -------LPAGSVAWPSRPAsfPGGRMLLYVATPALWRDGWrp------------------------------pLPpeat 287 Thermobifida...
Q1CW30          259 -----LKVDLFAIPDGVARA---TRGLRLVLATPAEFQRGWlp--dGFERvagtp--------pryvGRLPCIDAP---- 316 Myxococcus x...
jgi:Mmwyl1_2691 252 ------CEVWPRPPENFAQEiiSAGGLILTFLTPTIFANGWrp--kWLDKgipp----------gceHLHLE-------- 305 Marinomonas ...
jgi:Hhal_0628   251 -------VAAPVETSPEPAAieAEGRLRIVLTTPGIFPGGW-----QLPGlda-----------nglWHYPGGRAR---- 303 Halorhodospi...
Q2JN53          230 c--pKLQEQWQQLQALSQAAfcQAGRALAYLATPGVFIKKVegrslCRAWpwewr--------latpHPAHPLTGP---- 295 Synechococcu...
Q6ZEA9          230 r--pALDQQWQRLQTLSDQNyqQRQKAIAYLMTPGIFERGRdgvstCRPYpwew----------kltHNQGS-------- 289 Synechocysti...
A0B6W4          241 ----LSPGKGVSEIRQEIGPidGRVRFTLVHITPAFLGRWPrp--gES---------------------IPGVPGE---- 289 Methanothrix...
Q8TVU0          361 VLADRVieTR------RVS-TWSG-KRASPDHLA---------------AAEGTVlalgkldvdpgtpllLFPRMGDEDR 417 Methanopyrus...
O28413          272 VRSVNFigGKp----vIFS-GWDF-VTRKPKPTRy-------------aVPAGSV---------------YFVEFEGEVK 317 Archaeoglobu...
Q7MTH3          303 VKFASTevKDfaclltHVG-TRRFyNKKKKREEQnieevetalshqhelYARGSV---------------FYFDTKEQAN 366 Porphyromona...
Q47PK4          288 LVAAAVgsPLp-------------vATASPKRGFfrtrt------lrwaVPPGSV---------------YLLHFPDEET 333 Thermobifida...
Q1CW30          317 VVLRAAlvPWp----lDVS-GWDM-VRRRPRPTRr-------------wVPAGAV---------------YFFEKHSGGD 362 Myxococcus x...
jgi:Mmwyl1_2691 306 LKAAAV--DRw----qPQS-GWDL-ASNKPRASEr-------------mILAGAT---------------YWFAIVDGTA 349 Marinomonas ...
jgi:Hhal_0628   304 LVAAAV--PRg----qVIS-GWDL-AHHRPKPAQr-------------aAPAGTV---------------YWLEALEGGL 347 Halorhodospi...
Q2JN53          296 LVSVAT--GKp----vAISgRLRVdRPPEQRQMSlpap-------qvfaAPPGSI---------------YYLEQPAPLN 347 Synechococcu...
Q6ZEA9          290 FISMAT--DRa----vAISpRIRD-RQRNPGHSipap--------qvfaAPPGTV---------------YYLNQPQGLF 339 Synechocysti...
A0B6W4          290 VVSACV--GRa----lRIG-GWDS-VNRRPVELKp-------------fIPPGSV---------------WFCEAEADEL 333 Methanothrix...
Q8TVU0          418 ELLASRLA--------------------------FHLSGVGTAYALSL 439 Methanopyrus kandleri
O28413          318 LDMPYLKLg------------------------kLTKLGYGLCFMGVW 341 Archaeoglobus fulgidus
Q7MTH3          367 QFCEDLEKvp-----------------------nFHTIGYNHAIIIEP 391 Porphyromonas gingivalis
Q47PK4          334 AAAVASSWhgralapsadwihthegdhpptdappLHTAGFGIVLTGVW 381 Thermobifida fusca YX
Q1CW30          363 FTANELRAl------------------------wLASWGGGHAEALGQ 386 Myxococcus xanthus DK 1622
jgi:Mmwyl1_2691 350 SEQEIEKLwmahl----------------cddkqHNLNGFGLTLPMAY 381 Marinomonas sp. MWYL1
jgi:Hhal_0628   348 KPLRKLAE---------------------------------SGLWGMT 362 Halorhodospira halophila SL1
Q2JN53          348 QEEPELEDgrln------------------vfhrWRLLGYSELLWLPW 377 Synechococcus sp. JA-2-3B'a(2-13)
Q6ZEA9          340 ADQDNAPKhl----------------------qqTRKLGYSHLLWVNL 365 Synechocystis sp. PCC 6803
A0B6W4          334 NDVMSVSRig-----------------------eYTGFGFGEIALGIW 358 Methanothrix thermoacetophila PT
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