Conserved Protein Domain Family
Phage_holin_6_1

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pfam09682: Phage_holin_6_1 
Bacteriophage holin of superfamily 6 (Holin_LLH)
Phage_holin_6_1 or Holin_LLH identifies a family of phage holins from a number of phage and prophage regions of Gram-positive bacteria. Like other holins, it is large for holins (about 100-160 amino acids) with stretches of hydrophobic sequence and is encoded adjacent to lytic enzymes. Holin LLH family is found in phage of Firmicutes and have an N-terminal transmembrane segment.
Statistics
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PSSM-Id: 401571
Aligned: 13 rows
Threshold Bit Score: 67.7063
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q65PS1              3 VNQLLDLSIVVVSVAAVVVASVYAKHKia--idKKAAQGDLLAKAEKIvAQSVSPLVYQAEKR-GGDGEDKLTFVVQGLF 79  Lactobacil...
CDF08453            2 NEVLFEILKAVILLAIVLVVRYLIPWL------KLQVEGTKNEWLVKW-AELAVRSAEQTILG-DKTGPEKKAIVTKFLK 73 
jgi:Cphy_2850       2 NEILFSAIQIIVVILLGLVSRYVIPWL------KVKLDTEKASQILAW-IQTAVTAAEQIISG-ESKGIEKKAFVTEYMN 73 
CDC28102            5 IDITV-VLEIIISIVFILASKYIIPWL------NAKKQDQNLKNILQI-VEQVVKAANELGIT--GEIEDKAAYAWDEAI 74 
REF_PBI:SPO1_108    9 VQAGVEIIVIILGALLSLVSAKAVKVL------NTIKKKDETGIVDAV-TDAVVNLAEKELSG--AKGLEKRDYAVKKAV 79 
AKQ06885            9 LNLLRPTIMTGVTIILGFLGMKIKNYY------NVKISFEQQKQIANI-AKAAVMFVEQVAGE-HLLSDDKLSMAKHRAK 80 
SKLIDPC::KE3_1385   2 nDVILQGIMLILTGFAGFIVKTVKDYL-------FKEGGEKALRIVEIvAKNAVNAVEQIANE-DTKGEQKLTAAKTKVK 73 
Q8E0W4              5 ITQIITVSVPIFGIIAGILTHKVKKLL-------IKKGGEKAVKIAEIvARNAVEAVEQISVEvGIKGQDKLTEAKTAVI 77  Streptococ...
Q8DXL2              5 TDIIISSAMGILTILAGIAVQAVKVYL-------IKKGGEKAVLITEIlAKNAVNAVEQVATEtGFKGADKLTSAKAQIL 77  Streptococ...
WP_015043842       12 NELLQIVITIVIPFVGAYLVSLIKKHL-------TAKQIEIAKNIAGI----AVKFAQQSGLA----NADKFQLAFNTVK 76  unclassifi...
jgi:Desgi_4695      6 IQISYDVLAVLIPALVALLFELIRRKLgtenlnKIAVQLETKQDLALL----AVRFVEQVYKD--AGGQAKFNEALEWLS 79 
CDA90806            5 LLIITITLLIVVAAAAILFATPIRNLI------KKKTTKEEYDTLLAL-AEISVRWAKQWMDT--ATGAEKKEEVLRYLE 75 
Q65PS5              2 NNILVNVSAVIVALVLSYFVFWYRNHKie--idKKRAKGDALAFVVDTlGQVATNVVYDLKDN-SEKGTEKKEQAKVKIK 78  Lactobacil...
Q65PS1             80 LLLDMAHLpHPTMSFVKGMVEKSVTAMKQ 108 Lactobacillus johnsonii
CDF08453           74 EQLQKKNI-SISDEQLNTLIEAAVYAMKQ 101
jgi:Cphy_2850      74 KLLKEKGI-SITEEQLNLLIESAVKALNT 101
CDC28102           75 KILNKKGI-NFNEDELKMFIKAAVTNLRv 102
REF_PBI:SPO1_108   80 EILHSKGLkSITETEILAGIEAGVKKMPK 108
AKQ06885           81 VTLNQVGI-DITDEELTMWIEAFVGGLNH 108
SKLIDPC::KE3_1385  74 KALEQYNI-YLTDSQLEMFIEAAVKEMNN 101
Q8E0W4             78 DGLSQYNI-SLTETQLETFIEAAVKRMND 105 Streptococcus agalactiae serogroup V
Q8DXL2             78 AELQKYNI-HMSDDDLTLFVESAVKQMHD 105 Streptococcus agalactiae serogroup V
WP_015043842       77 SMASQHGI-KLTDEQWTSLVEAAVNEFKK 104 unclassified Dehalobacter
jgi:Desgi_4695     80 ARANEHGI-KITADEARGLIEAALRELKD 107
CDA90806           76 EKTSELGL-NITADDIDKAIEAAYEKVKK 103
Q65PS5             79 NFYADAHLpAPSDAQVSGAIEKAVAIMKM 107 Lactobacillus johnsonii
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